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Combined Intrathoracic and Subcutaneous Splenosis Discovered 51 Years after Abdominal Trauma.

Gleason JB, Hadeh A, Diacovo MJ, Schroeder JR - Case Rep Pulmonol (2015)

Bottom Line: This occurs after traumatic rupture of the spleen and is usually asymptomatic, only to be discovered incidentally on routine thoracic or abdominal imaging.This occurred in a 71-year-old male involved in a motor vehicle accident at age 19 requiring urgent splenectomy.He has a significant cigarette smoking history and was referred to our hospital for further evaluation of an abnormality seen on shoulder X-ray.

View Article: PubMed Central - PubMed

Affiliation: Department of Pulmonary and Critical Care Medicine, Cleveland Clinic Florida, 2950 Cleveland Clinic Boulevard, Weston, FL 33331, USA.

ABSTRACT
Splenosis is a rare condition that results from the autotransplantation of splenic parenchyma into unexpected locations such as the abdomen or subcutaneous tissue. In the presence of coexisting injury to the diaphragm intrathoracic transplantation can occur emerging as single or multiple pleural-based masses. This occurs after traumatic rupture of the spleen and is usually asymptomatic, only to be discovered incidentally on routine thoracic or abdominal imaging. To our knowledge this is the third documented case of combined intrathoracic and subcutaneous splenosis found in English literature. This occurred in a 71-year-old male involved in a motor vehicle accident at age 19 requiring urgent splenectomy. He has a significant cigarette smoking history and was referred to our hospital for further evaluation of an abnormality seen on shoulder X-ray.

No MeSH data available.


Related in: MedlinePlus

Hematoxylin & Eosin stain at 20x magnification identifying lipogranulomas present in our case.
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fig6: Hematoxylin & Eosin stain at 20x magnification identifying lipogranulomas present in our case.

Mentions: Because of his risk factors for primary lung malignancy he underwent left sided video-assisted thoracoscopic surgery (VATS) and biopsy. Surgical specimens demonstrated pleural-based masses which were grossly friable and maroon-tanned. Histologically, two well-delineated areas compatible with white and red pulp were noted (Figure 5). Occasional lipogranulomas were present on the red pulp (Figure 6). Immunophenotyping by immunohistochemistry and flow cytometry analysis revealed a preserved immunoarchitecture and absence of an abnormal B- or T-cell population, respectively (Figure 7). These findings supported the diagnosis of thoracic splenosis.


Combined Intrathoracic and Subcutaneous Splenosis Discovered 51 Years after Abdominal Trauma.

Gleason JB, Hadeh A, Diacovo MJ, Schroeder JR - Case Rep Pulmonol (2015)

Hematoxylin & Eosin stain at 20x magnification identifying lipogranulomas present in our case.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4510120&req=5

fig6: Hematoxylin & Eosin stain at 20x magnification identifying lipogranulomas present in our case.
Mentions: Because of his risk factors for primary lung malignancy he underwent left sided video-assisted thoracoscopic surgery (VATS) and biopsy. Surgical specimens demonstrated pleural-based masses which were grossly friable and maroon-tanned. Histologically, two well-delineated areas compatible with white and red pulp were noted (Figure 5). Occasional lipogranulomas were present on the red pulp (Figure 6). Immunophenotyping by immunohistochemistry and flow cytometry analysis revealed a preserved immunoarchitecture and absence of an abnormal B- or T-cell population, respectively (Figure 7). These findings supported the diagnosis of thoracic splenosis.

Bottom Line: This occurs after traumatic rupture of the spleen and is usually asymptomatic, only to be discovered incidentally on routine thoracic or abdominal imaging.This occurred in a 71-year-old male involved in a motor vehicle accident at age 19 requiring urgent splenectomy.He has a significant cigarette smoking history and was referred to our hospital for further evaluation of an abnormality seen on shoulder X-ray.

View Article: PubMed Central - PubMed

Affiliation: Department of Pulmonary and Critical Care Medicine, Cleveland Clinic Florida, 2950 Cleveland Clinic Boulevard, Weston, FL 33331, USA.

ABSTRACT
Splenosis is a rare condition that results from the autotransplantation of splenic parenchyma into unexpected locations such as the abdomen or subcutaneous tissue. In the presence of coexisting injury to the diaphragm intrathoracic transplantation can occur emerging as single or multiple pleural-based masses. This occurs after traumatic rupture of the spleen and is usually asymptomatic, only to be discovered incidentally on routine thoracic or abdominal imaging. To our knowledge this is the third documented case of combined intrathoracic and subcutaneous splenosis found in English literature. This occurred in a 71-year-old male involved in a motor vehicle accident at age 19 requiring urgent splenectomy. He has a significant cigarette smoking history and was referred to our hospital for further evaluation of an abnormality seen on shoulder X-ray.

No MeSH data available.


Related in: MedlinePlus