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Long-Term Results of Catheter-Directed Thrombolysis Combined with Iliac Vein Stenting for Iliofemoral Deep Vein Thrombosis.

Park C, So BJ - Vasc Specialist Int (2015)

Bottom Line: The validated outcome measures were compared between the treatment groups.Long term results of CDT in IFDVT were acceptable, and stent implantation to the iliac segment seems to have a good effect on the long term results.Therefore CDT with simultaneous stenting is recommended to improve long term results of IFDVT, if indicated.

View Article: PubMed Central - PubMed

Affiliation: Department of Vascular Surgery, Wonkwang University School of Medicine & Hospital, Iksan, Korea.

ABSTRACT

Purpose: We were going to access the effect of catheter-directed thrombolytic therapy (CDT) on post-thrombotic syndrome (PTS) and the long term effects of iliac vein stenting in acute iliofemoral deep vein thrombosis (IFDVT).

Materials and methods: Fifty-six limbs in fifty-one patients (46 unilateral, 5 bilateral) were included from November 2001 through December 2007. Patients were classified based on the method of treatment: with stent implantation (n=37) and without stent implantation (n=19). The Villalta scale was chosen to assess for severity of PTS. The validated outcome measures were compared between the treatment groups. Statistical analysis was estimated according to the Kaplan-Meier test and Pearson chi-square test.

Results: Mean age was 57±13 years (range, 27-76 years). Mean follow up duration was 56±12 months (range, 24-144 months). Overall 5-year primary patency rate was 66.1% (77.8% in the stenting group and 42.1% in the non-stenting group) and showed statistically significant difference between the two groups (P=0.02). The recurrence rate of deep vein thrombosis was 10/37 (27.1%) in the stenting group and 11/19 (57.9%) in the non-stenting group, respectively, which showed statistically significant difference between the two groups (P=0.024). Overall incidence of mild PTS was 8/30 (26.7%): 4/13 (30.8%) in the stenting group and 4/17 (23.5%) in the non-stenting group. None of the other factors showed statistically significant difference between the groups.

Conclusion: Long term results of CDT in IFDVT were acceptable, and stent implantation to the iliac segment seems to have a good effect on the long term results. Therefore CDT with simultaneous stenting is recommended to improve long term results of IFDVT, if indicated.

No MeSH data available.


Related in: MedlinePlus

Kaplan-Meier curve for primary/secondary patency rates in both groups. (A) Primary patency, (B) secondary patency.
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f2-vsi-31-47: Kaplan-Meier curve for primary/secondary patency rates in both groups. (A) Primary patency, (B) secondary patency.

Mentions: At 5 years, the overall primary patency rate was 66.0%, and the overall secondary patency rate was 85.6% (Fig. 1). The primary patency rates at 5 years for the stenting group and the non-stenting group were 77.8% and 42.1%, respectively, which was statistically significant (P=0.02; Fig. 2). The secondary patency rates at 5 years were 83.8% and 63.2%, respectively and there was no statistically significant difference between the two groups (P=0.97; Fig. 2).


Long-Term Results of Catheter-Directed Thrombolysis Combined with Iliac Vein Stenting for Iliofemoral Deep Vein Thrombosis.

Park C, So BJ - Vasc Specialist Int (2015)

Kaplan-Meier curve for primary/secondary patency rates in both groups. (A) Primary patency, (B) secondary patency.
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4508653&req=5

f2-vsi-31-47: Kaplan-Meier curve for primary/secondary patency rates in both groups. (A) Primary patency, (B) secondary patency.
Mentions: At 5 years, the overall primary patency rate was 66.0%, and the overall secondary patency rate was 85.6% (Fig. 1). The primary patency rates at 5 years for the stenting group and the non-stenting group were 77.8% and 42.1%, respectively, which was statistically significant (P=0.02; Fig. 2). The secondary patency rates at 5 years were 83.8% and 63.2%, respectively and there was no statistically significant difference between the two groups (P=0.97; Fig. 2).

Bottom Line: The validated outcome measures were compared between the treatment groups.Long term results of CDT in IFDVT were acceptable, and stent implantation to the iliac segment seems to have a good effect on the long term results.Therefore CDT with simultaneous stenting is recommended to improve long term results of IFDVT, if indicated.

View Article: PubMed Central - PubMed

Affiliation: Department of Vascular Surgery, Wonkwang University School of Medicine & Hospital, Iksan, Korea.

ABSTRACT

Purpose: We were going to access the effect of catheter-directed thrombolytic therapy (CDT) on post-thrombotic syndrome (PTS) and the long term effects of iliac vein stenting in acute iliofemoral deep vein thrombosis (IFDVT).

Materials and methods: Fifty-six limbs in fifty-one patients (46 unilateral, 5 bilateral) were included from November 2001 through December 2007. Patients were classified based on the method of treatment: with stent implantation (n=37) and without stent implantation (n=19). The Villalta scale was chosen to assess for severity of PTS. The validated outcome measures were compared between the treatment groups. Statistical analysis was estimated according to the Kaplan-Meier test and Pearson chi-square test.

Results: Mean age was 57±13 years (range, 27-76 years). Mean follow up duration was 56±12 months (range, 24-144 months). Overall 5-year primary patency rate was 66.1% (77.8% in the stenting group and 42.1% in the non-stenting group) and showed statistically significant difference between the two groups (P=0.02). The recurrence rate of deep vein thrombosis was 10/37 (27.1%) in the stenting group and 11/19 (57.9%) in the non-stenting group, respectively, which showed statistically significant difference between the two groups (P=0.024). Overall incidence of mild PTS was 8/30 (26.7%): 4/13 (30.8%) in the stenting group and 4/17 (23.5%) in the non-stenting group. None of the other factors showed statistically significant difference between the groups.

Conclusion: Long term results of CDT in IFDVT were acceptable, and stent implantation to the iliac segment seems to have a good effect on the long term results. Therefore CDT with simultaneous stenting is recommended to improve long term results of IFDVT, if indicated.

No MeSH data available.


Related in: MedlinePlus