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An Unusual Presentation of Cystic Nephroma in an Adult Man.

Dell'Atti L - Rare Tumors (2015)

Bottom Line: There are two peaks in the incidence of the tumor, with a bimodal distribution presenting in children between three months and two years, and in adults over 30-years of age.We report a case of CN in the middle part of the left kidney in a 66-year-old male that presented with a singular unilocular, well-circumscribed cyst containing numerous calcifications on the walls and with unremarkable thin or relatively thicker septa from the border with the renal parenchyma, but no solid components.Images, histopathological and immunohistochemical features, that are potentially useful for refining this lesion, are discussed.

View Article: PubMed Central - PubMed

Affiliation: Department of Urology, University Hospital St. Anna , Ferrara, Italy.

ABSTRACT
Cystic nephroma (CN) is an uncommon, benign lesion of the kidney, whose clinical presentation is nonspecific with symptoms such as flack pain, hematuria and urinary tract infection. There are two peaks in the incidence of the tumor, with a bimodal distribution presenting in children between three months and two years, and in adults over 30-years of age. We report a case of CN in the middle part of the left kidney in a 66-year-old male that presented with a singular unilocular, well-circumscribed cyst containing numerous calcifications on the walls and with unremarkable thin or relatively thicker septa from the border with the renal parenchyma, but no solid components. Laparoscopic nephrectomy was performed. Images, histopathological and immunohistochemical features, that are potentially useful for refining this lesion, are discussed.

No MeSH data available.


Related in: MedlinePlus

Macroscopic examination revealed a cystic mass, originated from the middle and upper part of the left kidney, with walls of hard consistency.
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fig002: Macroscopic examination revealed a cystic mass, originated from the middle and upper part of the left kidney, with walls of hard consistency.

Mentions: The mass was compressing the calycle system and vascular structures at hilum, but no peripheral invasion or distant metastases were detected. Based on the clinical and radiological findings, laparoscopic nephrectomy was performed to remove the tumor. Macroscopic examination revealed a cystic mass, originated from the middle and upper part of the left kidney, with walls of hard consistency, and the maximum thickness of 4mm, screeching to cutting (Figure 2). Microscopically the cyst was lined by a single layer flattened and several calcified areas. The cyst epithelial cells were strongly positive for keratin and epithelial membrane antigen but negative for F VIII, CD34, and vimentin. The septa were composed mainly of mature, predominantly collagenous fibrous tissue and contained dilated vessels. The final histopathological diagnosis was adult cystic nephroma. The patient was discharged 5 days after the operation. The vascular, ureteral, renal pelvis and capsular surgical margins were intact.


An Unusual Presentation of Cystic Nephroma in an Adult Man.

Dell'Atti L - Rare Tumors (2015)

Macroscopic examination revealed a cystic mass, originated from the middle and upper part of the left kidney, with walls of hard consistency.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4508646&req=5

fig002: Macroscopic examination revealed a cystic mass, originated from the middle and upper part of the left kidney, with walls of hard consistency.
Mentions: The mass was compressing the calycle system and vascular structures at hilum, but no peripheral invasion or distant metastases were detected. Based on the clinical and radiological findings, laparoscopic nephrectomy was performed to remove the tumor. Macroscopic examination revealed a cystic mass, originated from the middle and upper part of the left kidney, with walls of hard consistency, and the maximum thickness of 4mm, screeching to cutting (Figure 2). Microscopically the cyst was lined by a single layer flattened and several calcified areas. The cyst epithelial cells were strongly positive for keratin and epithelial membrane antigen but negative for F VIII, CD34, and vimentin. The septa were composed mainly of mature, predominantly collagenous fibrous tissue and contained dilated vessels. The final histopathological diagnosis was adult cystic nephroma. The patient was discharged 5 days after the operation. The vascular, ureteral, renal pelvis and capsular surgical margins were intact.

Bottom Line: There are two peaks in the incidence of the tumor, with a bimodal distribution presenting in children between three months and two years, and in adults over 30-years of age.We report a case of CN in the middle part of the left kidney in a 66-year-old male that presented with a singular unilocular, well-circumscribed cyst containing numerous calcifications on the walls and with unremarkable thin or relatively thicker septa from the border with the renal parenchyma, but no solid components.Images, histopathological and immunohistochemical features, that are potentially useful for refining this lesion, are discussed.

View Article: PubMed Central - PubMed

Affiliation: Department of Urology, University Hospital St. Anna , Ferrara, Italy.

ABSTRACT
Cystic nephroma (CN) is an uncommon, benign lesion of the kidney, whose clinical presentation is nonspecific with symptoms such as flack pain, hematuria and urinary tract infection. There are two peaks in the incidence of the tumor, with a bimodal distribution presenting in children between three months and two years, and in adults over 30-years of age. We report a case of CN in the middle part of the left kidney in a 66-year-old male that presented with a singular unilocular, well-circumscribed cyst containing numerous calcifications on the walls and with unremarkable thin or relatively thicker septa from the border with the renal parenchyma, but no solid components. Laparoscopic nephrectomy was performed. Images, histopathological and immunohistochemical features, that are potentially useful for refining this lesion, are discussed.

No MeSH data available.


Related in: MedlinePlus