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An Unusual Presentation of Cystic Nephroma in an Adult Man.

Dell'Atti L - Rare Tumors (2015)

Bottom Line: There are two peaks in the incidence of the tumor, with a bimodal distribution presenting in children between three months and two years, and in adults over 30-years of age.We report a case of CN in the middle part of the left kidney in a 66-year-old male that presented with a singular unilocular, well-circumscribed cyst containing numerous calcifications on the walls and with unremarkable thin or relatively thicker septa from the border with the renal parenchyma, but no solid components.Images, histopathological and immunohistochemical features, that are potentially useful for refining this lesion, are discussed.

View Article: PubMed Central - PubMed

Affiliation: Department of Urology, University Hospital St. Anna , Ferrara, Italy.

ABSTRACT
Cystic nephroma (CN) is an uncommon, benign lesion of the kidney, whose clinical presentation is nonspecific with symptoms such as flack pain, hematuria and urinary tract infection. There are two peaks in the incidence of the tumor, with a bimodal distribution presenting in children between three months and two years, and in adults over 30-years of age. We report a case of CN in the middle part of the left kidney in a 66-year-old male that presented with a singular unilocular, well-circumscribed cyst containing numerous calcifications on the walls and with unremarkable thin or relatively thicker septa from the border with the renal parenchyma, but no solid components. Laparoscopic nephrectomy was performed. Images, histopathological and immunohistochemical features, that are potentially useful for refining this lesion, are discussed.

No MeSH data available.


Related in: MedlinePlus

A) Computed tomography (CT) shows a 4.2×2.6 cm, unilocular, well-circumscribed cyst containing numerous calcifications on the walls; B) an enhanced CT scan showed a poorly enhancing cystic lesion protruding into sinus.
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fig001: A) Computed tomography (CT) shows a 4.2×2.6 cm, unilocular, well-circumscribed cyst containing numerous calcifications on the walls; B) an enhanced CT scan showed a poorly enhancing cystic lesion protruding into sinus.

Mentions: Physical examination was unremarkable except for a mild knocking pain in the left kidney area. Laboratory findings were within normal limits, excepting for microscopic hematuria. Urine cytology was negative for malignancy. He underwent abdominal ultrasound (US) in order to investigate possible cause of recurrence of urinary infection. The results of US demonstrated a well-demarcated cystic mass of the left kidney (about 4 cm in max. diameter) with thickened walls and hyperechoic appearance as large calcifications which occupied the middle part of the kidney. Computed tomography (CT) showed a 4.2×2.6 cm, unilocular, well-circumscribed cyst containing numerous calcifications on the walls and with unremarkable thin or relatively thicker septa from the border with the renal parenchyma, but no solid components. An enhanced CT scan showed a poorly enhancing cystic lesion protruding into sinus (Figure 1). Non-enhanced, cortical phase, and nephrographic phase CT attenuation measurements were 13.0, 15.1, and 24.4 HU, respectively. The renal cystic lesion had features suggestive of malignancy and was classified according to a scheme described by Bosniak as type III.


An Unusual Presentation of Cystic Nephroma in an Adult Man.

Dell'Atti L - Rare Tumors (2015)

A) Computed tomography (CT) shows a 4.2×2.6 cm, unilocular, well-circumscribed cyst containing numerous calcifications on the walls; B) an enhanced CT scan showed a poorly enhancing cystic lesion protruding into sinus.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4508646&req=5

fig001: A) Computed tomography (CT) shows a 4.2×2.6 cm, unilocular, well-circumscribed cyst containing numerous calcifications on the walls; B) an enhanced CT scan showed a poorly enhancing cystic lesion protruding into sinus.
Mentions: Physical examination was unremarkable except for a mild knocking pain in the left kidney area. Laboratory findings were within normal limits, excepting for microscopic hematuria. Urine cytology was negative for malignancy. He underwent abdominal ultrasound (US) in order to investigate possible cause of recurrence of urinary infection. The results of US demonstrated a well-demarcated cystic mass of the left kidney (about 4 cm in max. diameter) with thickened walls and hyperechoic appearance as large calcifications which occupied the middle part of the kidney. Computed tomography (CT) showed a 4.2×2.6 cm, unilocular, well-circumscribed cyst containing numerous calcifications on the walls and with unremarkable thin or relatively thicker septa from the border with the renal parenchyma, but no solid components. An enhanced CT scan showed a poorly enhancing cystic lesion protruding into sinus (Figure 1). Non-enhanced, cortical phase, and nephrographic phase CT attenuation measurements were 13.0, 15.1, and 24.4 HU, respectively. The renal cystic lesion had features suggestive of malignancy and was classified according to a scheme described by Bosniak as type III.

Bottom Line: There are two peaks in the incidence of the tumor, with a bimodal distribution presenting in children between three months and two years, and in adults over 30-years of age.We report a case of CN in the middle part of the left kidney in a 66-year-old male that presented with a singular unilocular, well-circumscribed cyst containing numerous calcifications on the walls and with unremarkable thin or relatively thicker septa from the border with the renal parenchyma, but no solid components.Images, histopathological and immunohistochemical features, that are potentially useful for refining this lesion, are discussed.

View Article: PubMed Central - PubMed

Affiliation: Department of Urology, University Hospital St. Anna , Ferrara, Italy.

ABSTRACT
Cystic nephroma (CN) is an uncommon, benign lesion of the kidney, whose clinical presentation is nonspecific with symptoms such as flack pain, hematuria and urinary tract infection. There are two peaks in the incidence of the tumor, with a bimodal distribution presenting in children between three months and two years, and in adults over 30-years of age. We report a case of CN in the middle part of the left kidney in a 66-year-old male that presented with a singular unilocular, well-circumscribed cyst containing numerous calcifications on the walls and with unremarkable thin or relatively thicker septa from the border with the renal parenchyma, but no solid components. Laparoscopic nephrectomy was performed. Images, histopathological and immunohistochemical features, that are potentially useful for refining this lesion, are discussed.

No MeSH data available.


Related in: MedlinePlus