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Patterns of Change During the Dermoscopic Follow-Up of Melanocytic Lesions in High Risk Patients.

Ungureanu L, Letcă A, Șenilă SC, Dănescu AS, Cosgarea R - Clujul Med (2015)

Bottom Line: Melanomas and melanocytic nevi that change over time display different change patterns, correlated with histopathological features.There were significant differences between the models of dermoscopic change characteristic to melanoma and those characteristic to melanocytic nevi.We observed changes with high specificity for the diagnosis of melanoma - asymmetric growth (Sp=90%), new structureless grey-blue areas (Sp=97.5%) or new grey-blue network (Sp=96.25%), new pseudopods or radial streaks (Sp=95%).

View Article: PubMed Central - PubMed

Affiliation: Department of Dermatology, Iuliu Hațieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.

ABSTRACT

Background: Melanomas and melanocytic nevi that change over time display different change patterns, correlated with histopathological features.

Methods: We performed a retrospective analysis of the dermoscopic images corresponding to 86 lesions excised due to the changes occurred during the follow-up period in patients at high risk for melanoma, and we drew a comparison between the changes occurring in melanomas and those occurring in melanocytic nevi.

Results: There were significant differences between the models of dermoscopic change characteristic to melanoma and those characteristic to melanocytic nevi. We observed changes with high specificity for the diagnosis of melanoma - asymmetric growth (Sp=90%), new structureless grey-blue areas (Sp=97.5%) or new grey-blue network (Sp=96.25%), new pseudopods or radial streaks (Sp=95%).

Conclusion: Our study highlights highly specific changes whose presence should raise the suspicion of melanoma and lead to the excision of the lesion.

No MeSH data available.


Related in: MedlinePlus

Patterns of change in melanoma, dysplastic melanocytic nevi and common melanocytic nevi during follow-up.
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Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC4508616&req=5

f1-cm8801p38: Patterns of change in melanoma, dysplastic melanocytic nevi and common melanocytic nevi during follow-up.

Mentions: The results of the present study demonstrate that there are statistically significant differences between the patterns of dermoscopic change characteristic of melanoma, dysplastic melanocytic nevi and common melanocytic nevi (Fig. 1).


Patterns of Change During the Dermoscopic Follow-Up of Melanocytic Lesions in High Risk Patients.

Ungureanu L, Letcă A, Șenilă SC, Dănescu AS, Cosgarea R - Clujul Med (2015)

Patterns of change in melanoma, dysplastic melanocytic nevi and common melanocytic nevi during follow-up.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4508616&req=5

f1-cm8801p38: Patterns of change in melanoma, dysplastic melanocytic nevi and common melanocytic nevi during follow-up.
Mentions: The results of the present study demonstrate that there are statistically significant differences between the patterns of dermoscopic change characteristic of melanoma, dysplastic melanocytic nevi and common melanocytic nevi (Fig. 1).

Bottom Line: Melanomas and melanocytic nevi that change over time display different change patterns, correlated with histopathological features.There were significant differences between the models of dermoscopic change characteristic to melanoma and those characteristic to melanocytic nevi.We observed changes with high specificity for the diagnosis of melanoma - asymmetric growth (Sp=90%), new structureless grey-blue areas (Sp=97.5%) or new grey-blue network (Sp=96.25%), new pseudopods or radial streaks (Sp=95%).

View Article: PubMed Central - PubMed

Affiliation: Department of Dermatology, Iuliu Hațieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.

ABSTRACT

Background: Melanomas and melanocytic nevi that change over time display different change patterns, correlated with histopathological features.

Methods: We performed a retrospective analysis of the dermoscopic images corresponding to 86 lesions excised due to the changes occurred during the follow-up period in patients at high risk for melanoma, and we drew a comparison between the changes occurring in melanomas and those occurring in melanocytic nevi.

Results: There were significant differences between the models of dermoscopic change characteristic to melanoma and those characteristic to melanocytic nevi. We observed changes with high specificity for the diagnosis of melanoma - asymmetric growth (Sp=90%), new structureless grey-blue areas (Sp=97.5%) or new grey-blue network (Sp=96.25%), new pseudopods or radial streaks (Sp=95%).

Conclusion: Our study highlights highly specific changes whose presence should raise the suspicion of melanoma and lead to the excision of the lesion.

No MeSH data available.


Related in: MedlinePlus