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Pathology Reporting of Thyroid Core Needle Biopsy: A Proposal of the Korean Endocrine Pathology Thyroid Core Needle Biopsy Study Group.

Jung CK, Min HS, Park HJ, Song DE, Kim JH, Park SY, Yoo H, Shin MK, Korean Endocrine Pathology Thyroid Core Needle Biopsy Study Gro - J Pathol Transl Med (2015)

Bottom Line: However, there is no consensus on the pathology reporting system for thyroid CNB.The Korean Endocrine Pathology Thyroid Core Needle Biopsy Study Group held a conference on thyroid CNB pathology and developed guidelines through contributions from the participants.This article discusses the outcome of the discussions that led to a consensus on the pathology reporting of thyroid CNB.

View Article: PubMed Central - PubMed

Affiliation: Department of Hospital Pathology, College of Medicine, The Catholic University of Korea, Seoul, Korea.

ABSTRACT
In recent years throughout Korea, the use of ultrasound-guided core needle biopsy (CNB) has become common for the preoperative diagnosis of thyroid nodules. However, there is no consensus on the pathology reporting system for thyroid CNB. The Korean Endocrine Pathology Thyroid Core Needle Biopsy Study Group held a conference on thyroid CNB pathology and developed guidelines through contributions from the participants. This article discusses the outcome of the discussions that led to a consensus on the pathology reporting of thyroid CNB.

No MeSH data available.


Related in: MedlinePlus

Diagnostic pitfalls in thyroid core needle biopsy. Follicular cells are smaller and darker in core needle biopsies in comparison (A) to resected specimens (B). These images have been obtained from the same patient as those pictured in Fig. 6. (C) The core needle biopsy shows the histologic features of a benign follicular nodule. (D) The high-power view of the boxed area in Fig. 8C shows nuclear vacuoles that mimic intranuclear cytoplasmic pseudoinclusions in papillary carcinoma (arrows).
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f8-jptm-49-4-288: Diagnostic pitfalls in thyroid core needle biopsy. Follicular cells are smaller and darker in core needle biopsies in comparison (A) to resected specimens (B). These images have been obtained from the same patient as those pictured in Fig. 6. (C) The core needle biopsy shows the histologic features of a benign follicular nodule. (D) The high-power view of the boxed area in Fig. 8C shows nuclear vacuoles that mimic intranuclear cytoplasmic pseudoinclusions in papillary carcinoma (arrows).

Mentions: The follicular cells in a CNB specimen appear smaller and show darker chromatin than in typical surgical specimens (Fig. 8A, B). Nuclear artifacts that mimic intranuclear cytoplasmic pseudoinclusions in papillary carcinoma may also be present in benign follicular cells (Fig. 8C, D). The artifactual vacuoles are irregularly shaped and appear pale on staining, whereas pseudoinclusions in papillary carcinoma are round and sharply delineated by the rim of the nuclear membrane.


Pathology Reporting of Thyroid Core Needle Biopsy: A Proposal of the Korean Endocrine Pathology Thyroid Core Needle Biopsy Study Group.

Jung CK, Min HS, Park HJ, Song DE, Kim JH, Park SY, Yoo H, Shin MK, Korean Endocrine Pathology Thyroid Core Needle Biopsy Study Gro - J Pathol Transl Med (2015)

Diagnostic pitfalls in thyroid core needle biopsy. Follicular cells are smaller and darker in core needle biopsies in comparison (A) to resected specimens (B). These images have been obtained from the same patient as those pictured in Fig. 6. (C) The core needle biopsy shows the histologic features of a benign follicular nodule. (D) The high-power view of the boxed area in Fig. 8C shows nuclear vacuoles that mimic intranuclear cytoplasmic pseudoinclusions in papillary carcinoma (arrows).
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4508566&req=5

f8-jptm-49-4-288: Diagnostic pitfalls in thyroid core needle biopsy. Follicular cells are smaller and darker in core needle biopsies in comparison (A) to resected specimens (B). These images have been obtained from the same patient as those pictured in Fig. 6. (C) The core needle biopsy shows the histologic features of a benign follicular nodule. (D) The high-power view of the boxed area in Fig. 8C shows nuclear vacuoles that mimic intranuclear cytoplasmic pseudoinclusions in papillary carcinoma (arrows).
Mentions: The follicular cells in a CNB specimen appear smaller and show darker chromatin than in typical surgical specimens (Fig. 8A, B). Nuclear artifacts that mimic intranuclear cytoplasmic pseudoinclusions in papillary carcinoma may also be present in benign follicular cells (Fig. 8C, D). The artifactual vacuoles are irregularly shaped and appear pale on staining, whereas pseudoinclusions in papillary carcinoma are round and sharply delineated by the rim of the nuclear membrane.

Bottom Line: However, there is no consensus on the pathology reporting system for thyroid CNB.The Korean Endocrine Pathology Thyroid Core Needle Biopsy Study Group held a conference on thyroid CNB pathology and developed guidelines through contributions from the participants.This article discusses the outcome of the discussions that led to a consensus on the pathology reporting of thyroid CNB.

View Article: PubMed Central - PubMed

Affiliation: Department of Hospital Pathology, College of Medicine, The Catholic University of Korea, Seoul, Korea.

ABSTRACT
In recent years throughout Korea, the use of ultrasound-guided core needle biopsy (CNB) has become common for the preoperative diagnosis of thyroid nodules. However, there is no consensus on the pathology reporting system for thyroid CNB. The Korean Endocrine Pathology Thyroid Core Needle Biopsy Study Group held a conference on thyroid CNB pathology and developed guidelines through contributions from the participants. This article discusses the outcome of the discussions that led to a consensus on the pathology reporting of thyroid CNB.

No MeSH data available.


Related in: MedlinePlus