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Pathology Reporting of Thyroid Core Needle Biopsy: A Proposal of the Korean Endocrine Pathology Thyroid Core Needle Biopsy Study Group.

Jung CK, Min HS, Park HJ, Song DE, Kim JH, Park SY, Yoo H, Shin MK, Korean Endocrine Pathology Thyroid Core Needle Biopsy Study Gro - J Pathol Transl Med (2015)

Bottom Line: However, there is no consensus on the pathology reporting system for thyroid CNB.The Korean Endocrine Pathology Thyroid Core Needle Biopsy Study Group held a conference on thyroid CNB pathology and developed guidelines through contributions from the participants.This article discusses the outcome of the discussions that led to a consensus on the pathology reporting of thyroid CNB.

View Article: PubMed Central - PubMed

Affiliation: Department of Hospital Pathology, College of Medicine, The Catholic University of Korea, Seoul, Korea.

ABSTRACT
In recent years throughout Korea, the use of ultrasound-guided core needle biopsy (CNB) has become common for the preoperative diagnosis of thyroid nodules. However, there is no consensus on the pathology reporting system for thyroid CNB. The Korean Endocrine Pathology Thyroid Core Needle Biopsy Study Group held a conference on thyroid CNB pathology and developed guidelines through contributions from the participants. This article discusses the outcome of the discussions that led to a consensus on the pathology reporting of thyroid CNB.

No MeSH data available.


Related in: MedlinePlus

The core needle biopsy of a follicular neoplasm with focal nuclear atypia. The images in the left and right columns show the findings of the core needle biopsy and the corresponding surgical specimen, respectively. (A) The ultrasound image shows a solid, homogeneous, hypoechoic, ovoid nodule with a peripheral halo. (B) The cut surface of the resected specimen corresponds to the ultrasound image in Fig. 5A. (C, D) The low-power view shows a follicular proliferative lesion with a fibrous capsule. (E) The high-power view of Fig. 5C reveals focal nuclear atypia. (F) The corresponding image in the surgical specimen more definitely shows the morphological features (e.g., nuclear enlargement, irregularity, clearing, and grooves) of a follicular variant of papillary carcinoma.
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f5-jptm-49-4-288: The core needle biopsy of a follicular neoplasm with focal nuclear atypia. The images in the left and right columns show the findings of the core needle biopsy and the corresponding surgical specimen, respectively. (A) The ultrasound image shows a solid, homogeneous, hypoechoic, ovoid nodule with a peripheral halo. (B) The cut surface of the resected specimen corresponds to the ultrasound image in Fig. 5A. (C, D) The low-power view shows a follicular proliferative lesion with a fibrous capsule. (E) The high-power view of Fig. 5C reveals focal nuclear atypia. (F) The corresponding image in the surgical specimen more definitely shows the morphological features (e.g., nuclear enlargement, irregularity, clearing, and grooves) of a follicular variant of papillary carcinoma.

Mentions: A recent study reported that the neoplasm or malignancy rate was not different among these architectural patterns of follicular lesions [15]. A CNB cannot discriminate between a follicular carcinoma and a follicular adenoma because the diagnosis of these neoplasms requires examination of the entire thick fibrous capsule. However, in a subset of this category, focal nuclear atypia raises the possibility of a follicular variant of papillary carcinoma (Fig. 5) [15,17,18]. A follicular variant of papillary carcinoma is reportedly the most common malignancy found after surgery of thyroid nodules with a preoperative diagnosis of follicular neoplasm [17,18].


Pathology Reporting of Thyroid Core Needle Biopsy: A Proposal of the Korean Endocrine Pathology Thyroid Core Needle Biopsy Study Group.

Jung CK, Min HS, Park HJ, Song DE, Kim JH, Park SY, Yoo H, Shin MK, Korean Endocrine Pathology Thyroid Core Needle Biopsy Study Gro - J Pathol Transl Med (2015)

The core needle biopsy of a follicular neoplasm with focal nuclear atypia. The images in the left and right columns show the findings of the core needle biopsy and the corresponding surgical specimen, respectively. (A) The ultrasound image shows a solid, homogeneous, hypoechoic, ovoid nodule with a peripheral halo. (B) The cut surface of the resected specimen corresponds to the ultrasound image in Fig. 5A. (C, D) The low-power view shows a follicular proliferative lesion with a fibrous capsule. (E) The high-power view of Fig. 5C reveals focal nuclear atypia. (F) The corresponding image in the surgical specimen more definitely shows the morphological features (e.g., nuclear enlargement, irregularity, clearing, and grooves) of a follicular variant of papillary carcinoma.
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4508566&req=5

f5-jptm-49-4-288: The core needle biopsy of a follicular neoplasm with focal nuclear atypia. The images in the left and right columns show the findings of the core needle biopsy and the corresponding surgical specimen, respectively. (A) The ultrasound image shows a solid, homogeneous, hypoechoic, ovoid nodule with a peripheral halo. (B) The cut surface of the resected specimen corresponds to the ultrasound image in Fig. 5A. (C, D) The low-power view shows a follicular proliferative lesion with a fibrous capsule. (E) The high-power view of Fig. 5C reveals focal nuclear atypia. (F) The corresponding image in the surgical specimen more definitely shows the morphological features (e.g., nuclear enlargement, irregularity, clearing, and grooves) of a follicular variant of papillary carcinoma.
Mentions: A recent study reported that the neoplasm or malignancy rate was not different among these architectural patterns of follicular lesions [15]. A CNB cannot discriminate between a follicular carcinoma and a follicular adenoma because the diagnosis of these neoplasms requires examination of the entire thick fibrous capsule. However, in a subset of this category, focal nuclear atypia raises the possibility of a follicular variant of papillary carcinoma (Fig. 5) [15,17,18]. A follicular variant of papillary carcinoma is reportedly the most common malignancy found after surgery of thyroid nodules with a preoperative diagnosis of follicular neoplasm [17,18].

Bottom Line: However, there is no consensus on the pathology reporting system for thyroid CNB.The Korean Endocrine Pathology Thyroid Core Needle Biopsy Study Group held a conference on thyroid CNB pathology and developed guidelines through contributions from the participants.This article discusses the outcome of the discussions that led to a consensus on the pathology reporting of thyroid CNB.

View Article: PubMed Central - PubMed

Affiliation: Department of Hospital Pathology, College of Medicine, The Catholic University of Korea, Seoul, Korea.

ABSTRACT
In recent years throughout Korea, the use of ultrasound-guided core needle biopsy (CNB) has become common for the preoperative diagnosis of thyroid nodules. However, there is no consensus on the pathology reporting system for thyroid CNB. The Korean Endocrine Pathology Thyroid Core Needle Biopsy Study Group held a conference on thyroid CNB pathology and developed guidelines through contributions from the participants. This article discusses the outcome of the discussions that led to a consensus on the pathology reporting of thyroid CNB.

No MeSH data available.


Related in: MedlinePlus