Limits...
Neoprene Orthopaedic Supports: An Underrecognised Cause of Allergic Contact Dermatitis.

Hawkey S, Ghaffar S - Case Rep Orthop (2015)

Bottom Line: All patients were patch tested to the British Society of Cutaneous Allergy Standard and rubber series and a cut piece from all the relevant supports.At 96 hours, all patients had a + reaction to mixed dialkylthiourea, diethylthiourea, and the supports' material.No other positive patch test reactions were identified.

View Article: PubMed Central - PubMed

Affiliation: Department of Dermatology, Ninewells Hospital & Medical School, University of Dundee, Dundee DD1 9SY, UK.

ABSTRACT
Thioureas, often contained within neoprene to provide water resistance, are an important cause of allergic contact dermatitis (ACD) in those who use neoprene products. We wish to present three cases of thiourea-induced ACD from three different orthopaedic supports containing neoprene. The first case was a 67-year-old woman who developed an itchy rash on her heel three weeks after using a neoprene insole for plantar fasciitis. The second case was a 47-year-old man who developed an itchy rash on his wrist after wearing neoprene wrist splints for psoriatic arthropathy. The third case was a 77-year-old woman who experienced a severe erythematous rash with blistering from a neoprene elbow brace she received following a humeral fracture. All patients were patch tested to the British Society of Cutaneous Allergy Standard and rubber series and a cut piece from all the relevant supports. At 96 hours, all patients had a + reaction to mixed dialkylthiourea, diethylthiourea, and the supports' material. No other positive patch test reactions were identified. As neoprene is fast becoming one of the most popular materials used for orthopaedic supports, awareness of this reaction and close liaison between dermatologists and orthopaedic surgeons are therefore essential to allow for early recognition of this complication.

No MeSH data available.


Related in: MedlinePlus

Itchy reaction to a wrist splint used for psoriatic arthropathy.
© Copyright Policy - open-access
Related In: Results  -  Collection


getmorefigures.php?uid=PMC4508468&req=5

fig1: Itchy reaction to a wrist splint used for psoriatic arthropathy.

Mentions: The first case was a 67-year-old lady who presented with an itchy dermatitis on her heel three weeks after she used a neoprene insole as treatment for her plantar fasciitis. The second case was a 47-year-old man who developed an itchy rash on his wrist after wearing three different types of neoprene wrist splints for his psoriatic arthropathy (Figure 1). The rash would typically appear 24–48 hours after he started wearing each splint. The third case was a 77-year-old lady who fractured her humerus and was given a neoprene elbow brace. A month after she started using it, she developed a severe, itchy erythematous rash with blistering over the skin in contact with the brace material (Figure 2). All three patients were patch tested to the British Society of Cutaneous Allergy (BSCA) Standard and rubber series along with a cut piece from all the relevant supports. At 96 hours, all three patients had a + reaction to mixed dialkylthiourea, diethylthiourea, and the supports' material (Figure 3). The BSCA Standard and rubber series encompasses a range of materials including common preservatives, dyes, excipients of topical medicaments, and rubber accelerators. In all three patients, no other positive patch test reactions were identified.


Neoprene Orthopaedic Supports: An Underrecognised Cause of Allergic Contact Dermatitis.

Hawkey S, Ghaffar S - Case Rep Orthop (2015)

Itchy reaction to a wrist splint used for psoriatic arthropathy.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4508468&req=5

fig1: Itchy reaction to a wrist splint used for psoriatic arthropathy.
Mentions: The first case was a 67-year-old lady who presented with an itchy dermatitis on her heel three weeks after she used a neoprene insole as treatment for her plantar fasciitis. The second case was a 47-year-old man who developed an itchy rash on his wrist after wearing three different types of neoprene wrist splints for his psoriatic arthropathy (Figure 1). The rash would typically appear 24–48 hours after he started wearing each splint. The third case was a 77-year-old lady who fractured her humerus and was given a neoprene elbow brace. A month after she started using it, she developed a severe, itchy erythematous rash with blistering over the skin in contact with the brace material (Figure 2). All three patients were patch tested to the British Society of Cutaneous Allergy (BSCA) Standard and rubber series along with a cut piece from all the relevant supports. At 96 hours, all three patients had a + reaction to mixed dialkylthiourea, diethylthiourea, and the supports' material (Figure 3). The BSCA Standard and rubber series encompasses a range of materials including common preservatives, dyes, excipients of topical medicaments, and rubber accelerators. In all three patients, no other positive patch test reactions were identified.

Bottom Line: All patients were patch tested to the British Society of Cutaneous Allergy Standard and rubber series and a cut piece from all the relevant supports.At 96 hours, all patients had a + reaction to mixed dialkylthiourea, diethylthiourea, and the supports' material.No other positive patch test reactions were identified.

View Article: PubMed Central - PubMed

Affiliation: Department of Dermatology, Ninewells Hospital & Medical School, University of Dundee, Dundee DD1 9SY, UK.

ABSTRACT
Thioureas, often contained within neoprene to provide water resistance, are an important cause of allergic contact dermatitis (ACD) in those who use neoprene products. We wish to present three cases of thiourea-induced ACD from three different orthopaedic supports containing neoprene. The first case was a 67-year-old woman who developed an itchy rash on her heel three weeks after using a neoprene insole for plantar fasciitis. The second case was a 47-year-old man who developed an itchy rash on his wrist after wearing neoprene wrist splints for psoriatic arthropathy. The third case was a 77-year-old woman who experienced a severe erythematous rash with blistering from a neoprene elbow brace she received following a humeral fracture. All patients were patch tested to the British Society of Cutaneous Allergy Standard and rubber series and a cut piece from all the relevant supports. At 96 hours, all patients had a + reaction to mixed dialkylthiourea, diethylthiourea, and the supports' material. No other positive patch test reactions were identified. As neoprene is fast becoming one of the most popular materials used for orthopaedic supports, awareness of this reaction and close liaison between dermatologists and orthopaedic surgeons are therefore essential to allow for early recognition of this complication.

No MeSH data available.


Related in: MedlinePlus