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Clinical outcomes of wavefront-guided laser in situ keratomileusis to treat moderate-to-high astigmatism.

Schallhorn SC, Venter JA, Hannan SJ, Hettinger KA - Clin Ophthalmol (2015)

Bottom Line: Preoperative refractive cylinder ranged from -2.00 D to -6.00 D (mean -2.76±0.81 D), and the sphere was between 0.00 D and -9.75 D (mean -2.79±2.32 D).The mean correction ratio for refractive cylinder was 0.92±0.14, the mean error of angle was -0.45°±2.99°, and the mean error vector was 0.37±0.38 D.A statistically significant correlation was found between the error of magnitude (arithmetic difference in the magnitudes between surgically induced refractive correction and intended refractive correction) and the intended refractive correction (r=0.26, P<0.01).

View Article: PubMed Central - PubMed

Affiliation: University of California, San Francisco, CA, USA ; Optical Express, Glasgow, UK.

ABSTRACT

Purpose: The purpose of this study was to evaluate the refractive and visual outcomes of wavefront-guided laser in situ keratomileusis (LASIK) in eyes with myopic astigmatism and cylindrical component ≥2.0 diopter (D).

Methods: In this retrospective study, 611 eyes that underwent LASIK for simple or compound myopic astigmatism were analyzed. Preoperative refractive cylinder ranged from -2.00 D to -6.00 D (mean -2.76±0.81 D), and the sphere was between 0.00 D and -9.75 D (mean -2.79±2.32 D). Predictability, visual outcomes, and vector analysis of changes in refractive astigmatism were evaluated.

Results: At 3 months after LASIK, 83.8% of eyes had uncorrected distance visual acuity of 20/20 or better, 90.3% had manifest spherical equivalent within ±0.50 D, and 79.1% had residual refractive cylinder within ±0.50 D of intended correction. The mean correction ratio for refractive cylinder was 0.92±0.14, the mean error of angle was -0.45°±2.99°, and the mean error vector was 0.37±0.38 D. A statistically significant correlation was found between the error of magnitude (arithmetic difference in the magnitudes between surgically induced refractive correction and intended refractive correction) and the intended refractive correction (r=0.26, P<0.01).

Conclusion: Wavefront-guided LASIK for the correction of myopic astigmatism is safe, effective, and predictable.

No MeSH data available.


Related in: MedlinePlus

Predictability of MSE at 3 months postoperatively.Notes: The area between two dotted lines is the postoperative MSE within ±1.00 D. The solid red line represents linear regression.Abbreviations: MSE, manifest spherical equivalent; D, diopter.
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f2-opth-9-1291: Predictability of MSE at 3 months postoperatively.Notes: The area between two dotted lines is the postoperative MSE within ±1.00 D. The solid red line represents linear regression.Abbreviations: MSE, manifest spherical equivalent; D, diopter.

Mentions: Figure 2 plots attempted MSE against achieved MSE at 3 months postoperatively. The linear regression of the scattergram has a slope of 0.98 and the intercept of −0.07. At 3 months, 90.3% (n=552) of eyes were within ±0.50 D, and 99.2% (n=606) were within ±1.0 D of emmetropia. The percentage of eyes with residual refractive cylinder of ≤0.50 D, ≤0.75 D, and ≤1.00 D was 79.1% (483 eyes), 88.5% (541 eyes), and 95.7% (585 eyes), respectively. Table 3 shows the stability of refractive error between 1 week and 1 month, and between 1 month and 3 months visits. There was a small, but statistically significant change in refractive cylinder between 1 month and 3 months (−0.03±0.34 D, P=0.01), while sphere and MSE remained stable between the two visits.


Clinical outcomes of wavefront-guided laser in situ keratomileusis to treat moderate-to-high astigmatism.

Schallhorn SC, Venter JA, Hannan SJ, Hettinger KA - Clin Ophthalmol (2015)

Predictability of MSE at 3 months postoperatively.Notes: The area between two dotted lines is the postoperative MSE within ±1.00 D. The solid red line represents linear regression.Abbreviations: MSE, manifest spherical equivalent; D, diopter.
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4508064&req=5

f2-opth-9-1291: Predictability of MSE at 3 months postoperatively.Notes: The area between two dotted lines is the postoperative MSE within ±1.00 D. The solid red line represents linear regression.Abbreviations: MSE, manifest spherical equivalent; D, diopter.
Mentions: Figure 2 plots attempted MSE against achieved MSE at 3 months postoperatively. The linear regression of the scattergram has a slope of 0.98 and the intercept of −0.07. At 3 months, 90.3% (n=552) of eyes were within ±0.50 D, and 99.2% (n=606) were within ±1.0 D of emmetropia. The percentage of eyes with residual refractive cylinder of ≤0.50 D, ≤0.75 D, and ≤1.00 D was 79.1% (483 eyes), 88.5% (541 eyes), and 95.7% (585 eyes), respectively. Table 3 shows the stability of refractive error between 1 week and 1 month, and between 1 month and 3 months visits. There was a small, but statistically significant change in refractive cylinder between 1 month and 3 months (−0.03±0.34 D, P=0.01), while sphere and MSE remained stable between the two visits.

Bottom Line: Preoperative refractive cylinder ranged from -2.00 D to -6.00 D (mean -2.76±0.81 D), and the sphere was between 0.00 D and -9.75 D (mean -2.79±2.32 D).The mean correction ratio for refractive cylinder was 0.92±0.14, the mean error of angle was -0.45°±2.99°, and the mean error vector was 0.37±0.38 D.A statistically significant correlation was found between the error of magnitude (arithmetic difference in the magnitudes between surgically induced refractive correction and intended refractive correction) and the intended refractive correction (r=0.26, P<0.01).

View Article: PubMed Central - PubMed

Affiliation: University of California, San Francisco, CA, USA ; Optical Express, Glasgow, UK.

ABSTRACT

Purpose: The purpose of this study was to evaluate the refractive and visual outcomes of wavefront-guided laser in situ keratomileusis (LASIK) in eyes with myopic astigmatism and cylindrical component ≥2.0 diopter (D).

Methods: In this retrospective study, 611 eyes that underwent LASIK for simple or compound myopic astigmatism were analyzed. Preoperative refractive cylinder ranged from -2.00 D to -6.00 D (mean -2.76±0.81 D), and the sphere was between 0.00 D and -9.75 D (mean -2.79±2.32 D). Predictability, visual outcomes, and vector analysis of changes in refractive astigmatism were evaluated.

Results: At 3 months after LASIK, 83.8% of eyes had uncorrected distance visual acuity of 20/20 or better, 90.3% had manifest spherical equivalent within ±0.50 D, and 79.1% had residual refractive cylinder within ±0.50 D of intended correction. The mean correction ratio for refractive cylinder was 0.92±0.14, the mean error of angle was -0.45°±2.99°, and the mean error vector was 0.37±0.38 D. A statistically significant correlation was found between the error of magnitude (arithmetic difference in the magnitudes between surgically induced refractive correction and intended refractive correction) and the intended refractive correction (r=0.26, P<0.01).

Conclusion: Wavefront-guided LASIK for the correction of myopic astigmatism is safe, effective, and predictable.

No MeSH data available.


Related in: MedlinePlus