Limits...
Sporadic Hemangioblastoma in the Pituitary Stalk: A Case Report and Review of the Literature.

Lee GI, Kim JM, Choi KS, Kim CH - J Korean Neurosurg Soc (2015)

Bottom Line: Most pituitary stalk hemangioblastomas reported in the literature were associated with von Hippel-Lindau (VHL) disease.Here, we report only the 3rd case of sporadic pituitary stalk hemangioblastoma diagnosed in a 60-year-old woman.Despite the danger of potential complications due to excessive vascularity or proximity to important neural structures, the tumor in our case was successfully removed while preserving pituitary function.

View Article: PubMed Central - PubMed

Affiliation: Department of Neurosurgery, Hanyang University Guri Hospital, Guri, Korea.

ABSTRACT
Hemangioblastomas in the pituitary stalk are especially rare. Most pituitary stalk hemangioblastomas reported in the literature were associated with von Hippel-Lindau (VHL) disease. Here, we report only the 3rd case of sporadic pituitary stalk hemangioblastoma diagnosed in a 60-year-old woman. Despite the danger of potential complications due to excessive vascularity or proximity to important neural structures, the tumor in our case was successfully removed while preserving pituitary function. In this case, complete surgical excision was shown to be an effective treatment option for symptomatic pituitary stalk hemangioblastoma, and we suggest careful evaluation of any highly enhancing mass with a signal void in the pituitary stalk preoperatively, even if no VHL disease is evident.

No MeSH data available.


Related in: MedlinePlus

Photomicrographic view of the tumor specimens showing a vascular lesion composed of prominent thin-walled vessels with vacuolated stromal cells (Hematoxylin and eosin, ×50) (A). Blue circles indicate positively stained endothelial cells (Immunostain for CD34 stain, ×200) (B).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC4502246&req=5

Figure 3: Photomicrographic view of the tumor specimens showing a vascular lesion composed of prominent thin-walled vessels with vacuolated stromal cells (Hematoxylin and eosin, ×50) (A). Blue circles indicate positively stained endothelial cells (Immunostain for CD34 stain, ×200) (B).

Mentions: Histological findings showed a vascularized mass composed of numerous thin-walled vascular channels lined endothelial cells and numerous ovoid, vacuolated stromal cells in a hematoxyline and eosin stain. This is consistent with the typical well-known morphology of HBLs. Mitotic figures were rare. Immunohistochemical staining was performed with antibody for CD 34. Endothelial cells showed a positive reaction for CD 34 (Fig. 3).


Sporadic Hemangioblastoma in the Pituitary Stalk: A Case Report and Review of the Literature.

Lee GI, Kim JM, Choi KS, Kim CH - J Korean Neurosurg Soc (2015)

Photomicrographic view of the tumor specimens showing a vascular lesion composed of prominent thin-walled vessels with vacuolated stromal cells (Hematoxylin and eosin, ×50) (A). Blue circles indicate positively stained endothelial cells (Immunostain for CD34 stain, ×200) (B).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4502246&req=5

Figure 3: Photomicrographic view of the tumor specimens showing a vascular lesion composed of prominent thin-walled vessels with vacuolated stromal cells (Hematoxylin and eosin, ×50) (A). Blue circles indicate positively stained endothelial cells (Immunostain for CD34 stain, ×200) (B).
Mentions: Histological findings showed a vascularized mass composed of numerous thin-walled vascular channels lined endothelial cells and numerous ovoid, vacuolated stromal cells in a hematoxyline and eosin stain. This is consistent with the typical well-known morphology of HBLs. Mitotic figures were rare. Immunohistochemical staining was performed with antibody for CD 34. Endothelial cells showed a positive reaction for CD 34 (Fig. 3).

Bottom Line: Most pituitary stalk hemangioblastomas reported in the literature were associated with von Hippel-Lindau (VHL) disease.Here, we report only the 3rd case of sporadic pituitary stalk hemangioblastoma diagnosed in a 60-year-old woman.Despite the danger of potential complications due to excessive vascularity or proximity to important neural structures, the tumor in our case was successfully removed while preserving pituitary function.

View Article: PubMed Central - PubMed

Affiliation: Department of Neurosurgery, Hanyang University Guri Hospital, Guri, Korea.

ABSTRACT
Hemangioblastomas in the pituitary stalk are especially rare. Most pituitary stalk hemangioblastomas reported in the literature were associated with von Hippel-Lindau (VHL) disease. Here, we report only the 3rd case of sporadic pituitary stalk hemangioblastoma diagnosed in a 60-year-old woman. Despite the danger of potential complications due to excessive vascularity or proximity to important neural structures, the tumor in our case was successfully removed while preserving pituitary function. In this case, complete surgical excision was shown to be an effective treatment option for symptomatic pituitary stalk hemangioblastoma, and we suggest careful evaluation of any highly enhancing mass with a signal void in the pituitary stalk preoperatively, even if no VHL disease is evident.

No MeSH data available.


Related in: MedlinePlus