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Amniotic Membrane Transplant with a Special Technique (Motowa's Sandwich Technique) in Mooren's Ulcer.

Al Motowa S, Al Zobidi M - Middle East Afr J Ophthalmol (2015 Jul-Sep)

Bottom Line: At 4 weeks postoperatively, visual acuity improved in the right eye to 20/160 with pinhole, and there was no fluorescein staining.Amniotic membrane transplant with "Motowa's sandwich technique" resulted in the preservation of the anatomical integrity and progression of disease was halted along with an improved vision.Further study on a large cohort of patients is required for evidence-based data to verify the outcome of this initial case report.

View Article: PubMed Central - PubMed

Affiliation: Cornea and Anterior Segment Division, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.

ABSTRACT
To illustrate amniotic membrane transplant (AMT) with a novel surgical technique ("sandwich technique") for treating patients with malignant Mooren's ulcer. A case report of a patient with bilateral, malignant Mooren's ulcer who had undergone systemic steroid therapy and topical immunosuppresive therapy to stabilize his condition. However, perforation of cornea occurred in one eye. AMT with a new surgical technique ("Motowa's sandwich technique") was performed to treat this case. On the 1(st) day postoperatively, there was no pain, no photophobia, and visual acuity was same as preoperatively. At 4 weeks postoperatively, visual acuity improved in the right eye to 20/160 with pinhole, and there was no fluorescein staining. The right eye was quiet. Amniotic membrane transplant with "Motowa's sandwich technique" resulted in the preservation of the anatomical integrity and progression of disease was halted along with an improved vision. This technique is a novel surgical modality in treating Mooren's ulcer. Further study on a large cohort of patients is required for evidence-based data to verify the outcome of this initial case report.

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6 years after surgery with peripheral corneal scarring and quite eye
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Figure 2: 6 years after surgery with peripheral corneal scarring and quite eye

Mentions: At last visit after 6 years, the patient denied pain or photophobia. Visual acuity as 4/200 in the right eye and 20/125 improving with a pinhole to 20/60 in the left eye. Intraocular pressure was 11 mm Hg and 17 mm Hg in the right and left eyes respectively. Slit-lamp examination of the right eye showed a clear corneal tectonic graft and with no fluorescein staining and a quiet eye [Figure 2]. The left eye was quiet with a clear central cornea and no fluorescein staining, and the patient had no complaints.


Amniotic Membrane Transplant with a Special Technique (Motowa's Sandwich Technique) in Mooren's Ulcer.

Al Motowa S, Al Zobidi M - Middle East Afr J Ophthalmol (2015 Jul-Sep)

6 years after surgery with peripheral corneal scarring and quite eye
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4502187&req=5

Figure 2: 6 years after surgery with peripheral corneal scarring and quite eye
Mentions: At last visit after 6 years, the patient denied pain or photophobia. Visual acuity as 4/200 in the right eye and 20/125 improving with a pinhole to 20/60 in the left eye. Intraocular pressure was 11 mm Hg and 17 mm Hg in the right and left eyes respectively. Slit-lamp examination of the right eye showed a clear corneal tectonic graft and with no fluorescein staining and a quiet eye [Figure 2]. The left eye was quiet with a clear central cornea and no fluorescein staining, and the patient had no complaints.

Bottom Line: At 4 weeks postoperatively, visual acuity improved in the right eye to 20/160 with pinhole, and there was no fluorescein staining.Amniotic membrane transplant with "Motowa's sandwich technique" resulted in the preservation of the anatomical integrity and progression of disease was halted along with an improved vision.Further study on a large cohort of patients is required for evidence-based data to verify the outcome of this initial case report.

View Article: PubMed Central - PubMed

Affiliation: Cornea and Anterior Segment Division, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.

ABSTRACT
To illustrate amniotic membrane transplant (AMT) with a novel surgical technique ("sandwich technique") for treating patients with malignant Mooren's ulcer. A case report of a patient with bilateral, malignant Mooren's ulcer who had undergone systemic steroid therapy and topical immunosuppresive therapy to stabilize his condition. However, perforation of cornea occurred in one eye. AMT with a new surgical technique ("Motowa's sandwich technique") was performed to treat this case. On the 1(st) day postoperatively, there was no pain, no photophobia, and visual acuity was same as preoperatively. At 4 weeks postoperatively, visual acuity improved in the right eye to 20/160 with pinhole, and there was no fluorescein staining. The right eye was quiet. Amniotic membrane transplant with "Motowa's sandwich technique" resulted in the preservation of the anatomical integrity and progression of disease was halted along with an improved vision. This technique is a novel surgical modality in treating Mooren's ulcer. Further study on a large cohort of patients is required for evidence-based data to verify the outcome of this initial case report.

Show MeSH
Related in: MedlinePlus