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Weaning from mechanical ventilation: a cross-sectional study of reference values and the discriminative validity of aging.

Corbellini C, Trevisan CB, Villafañe JH, Doval da Costa A, Vieira SR - J Phys Ther Sci (2015)

Bottom Line: [Purpose] To evaluate pre-extubation variables and check the discriminative validity of age as well as its correlation with weaning failure in elderly patients. [Subjects and Methods] Two hundred thirty-nine consecutive patients (48% female) who were on mechanical ventilation and had undergone orotracheal intubation were divided into four subgroups according to their age: <59 years, 60-69 years, 70-79 years, and >80 years old.Elderly patients presented higher f/VT and f values and lower VT values.The areas under the receiver operating characteristic curves for f/VT ratio were smaller than those published previously. [Conclusion] Our results indicate that aging influences weaning criteria without causing an increase in weaning failure.

View Article: PubMed Central - PubMed

Affiliation: Postgraduate Program in Medical Sciences, Medical School, Universidade Federal do Rio Grande do Sul, Brazil ; Casa di Cura Villa Serena, Italy.

ABSTRACT
[Purpose] To evaluate pre-extubation variables and check the discriminative validity of age as well as its correlation with weaning failure in elderly patients. [Subjects and Methods] Two hundred thirty-nine consecutive patients (48% female) who were on mechanical ventilation and had undergone orotracheal intubation were divided into four subgroups according to their age: <59 years, 60-69 years, 70-79 years, and >80 years old. The expiratory volume (VE), respiratory frequency (f), tidal volume (VT), and respiratory frequency/tidal volume ratio (f/VT) were used to examine differences in weaning parameters between the four subgroups, and age was correlated with weaning failure. [Results] The rate of weaning failure was 27.8% in patients aged >80 years and 22.1% in patients aged <60 years old. Elderly patients presented higher f/VT and f values and lower VT values. The areas under the receiver operating characteristic curves for f/VT ratio were smaller than those published previously. [Conclusion] Our results indicate that aging influences weaning criteria without causing an increase in weaning failure.

No MeSH data available.


Related in: MedlinePlus

ROC curves for f/VT ratio in all patients (n=239), the adult group(n=128), and the elderly group (n=111) Blue line: T0; red line: T30. AUC: area underthe curve; CI: confidence interval
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fig_001: ROC curves for f/VT ratio in all patients (n=239), the adult group(n=128), and the elderly group (n=111) Blue line: T0; red line: T30. AUC: area underthe curve; CI: confidence interval

Mentions: T0: time of first assessment of weaning parameters during spontaneous breathingtrial; T30: 30 minutes after first measurements; f/VT: ratio of respiratoryfrequency to tidal volume. a: non-significant ANOVA forrepeated measures of time, group, and interaction. *: p <0.05 in ttest for independent samples


Weaning from mechanical ventilation: a cross-sectional study of reference values and the discriminative validity of aging.

Corbellini C, Trevisan CB, Villafañe JH, Doval da Costa A, Vieira SR - J Phys Ther Sci (2015)

ROC curves for f/VT ratio in all patients (n=239), the adult group(n=128), and the elderly group (n=111) Blue line: T0; red line: T30. AUC: area underthe curve; CI: confidence interval
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4500017&req=5

fig_001: ROC curves for f/VT ratio in all patients (n=239), the adult group(n=128), and the elderly group (n=111) Blue line: T0; red line: T30. AUC: area underthe curve; CI: confidence interval
Mentions: T0: time of first assessment of weaning parameters during spontaneous breathingtrial; T30: 30 minutes after first measurements; f/VT: ratio of respiratoryfrequency to tidal volume. a: non-significant ANOVA forrepeated measures of time, group, and interaction. *: p <0.05 in ttest for independent samples

Bottom Line: [Purpose] To evaluate pre-extubation variables and check the discriminative validity of age as well as its correlation with weaning failure in elderly patients. [Subjects and Methods] Two hundred thirty-nine consecutive patients (48% female) who were on mechanical ventilation and had undergone orotracheal intubation were divided into four subgroups according to their age: <59 years, 60-69 years, 70-79 years, and >80 years old.Elderly patients presented higher f/VT and f values and lower VT values.The areas under the receiver operating characteristic curves for f/VT ratio were smaller than those published previously. [Conclusion] Our results indicate that aging influences weaning criteria without causing an increase in weaning failure.

View Article: PubMed Central - PubMed

Affiliation: Postgraduate Program in Medical Sciences, Medical School, Universidade Federal do Rio Grande do Sul, Brazil ; Casa di Cura Villa Serena, Italy.

ABSTRACT
[Purpose] To evaluate pre-extubation variables and check the discriminative validity of age as well as its correlation with weaning failure in elderly patients. [Subjects and Methods] Two hundred thirty-nine consecutive patients (48% female) who were on mechanical ventilation and had undergone orotracheal intubation were divided into four subgroups according to their age: <59 years, 60-69 years, 70-79 years, and >80 years old. The expiratory volume (VE), respiratory frequency (f), tidal volume (VT), and respiratory frequency/tidal volume ratio (f/VT) were used to examine differences in weaning parameters between the four subgroups, and age was correlated with weaning failure. [Results] The rate of weaning failure was 27.8% in patients aged >80 years and 22.1% in patients aged <60 years old. Elderly patients presented higher f/VT and f values and lower VT values. The areas under the receiver operating characteristic curves for f/VT ratio were smaller than those published previously. [Conclusion] Our results indicate that aging influences weaning criteria without causing an increase in weaning failure.

No MeSH data available.


Related in: MedlinePlus