Limits...
A Case of Posterior Mediastinal Plasmacytoma Confounded by Community-Acquired Pneumonia.

Heo D, Boo KY, Jwa H, Lee HY, Kim J, Kim ST, Seo HM, Han SH, Maeng YH, Lee JH - Tuberc Respir Dis (Seoul) (2015)

Bottom Line: A 67-year-old man recovered after antibiotic treatment for community-acquired pneumonia.Follow-up chest computed tomography (CT) revealed an increase in the extent of the right posterior mediastinal mass that we had considered to be pneumonic consolidations on previous CT scans.Through percutaneous needle biopsy, we diagnosed IgG kappa type extramedullary plasmacytoma of the posterior mediastinum.

View Article: PubMed Central - PubMed

Affiliation: Department of Internal Medicine, Jeju National University Hospital, Jeju National University School of Medicine, Jeju, Korea.

ABSTRACT
Plasmacytomas are extramedullary accumulations of plasma cells originating from soft tissue. Mediastinal plasmacytoma is a rare presentation. A 67-year-old man recovered after antibiotic treatment for community-acquired pneumonia. However, on convalescent chest radiography after 3 months, mass like lesion at the right lower lung field was newly detected. Follow-up chest computed tomography (CT) revealed an increase in the extent of the right posterior mediastinal mass that we had considered to be pneumonic consolidations on previous CT scans. Through percutaneous needle biopsy, we diagnosed IgG kappa type extramedullary plasmacytoma of the posterior mediastinum.

No MeSH data available.


Related in: MedlinePlus

(A) Microscopic examination showing diffuse infiltrates of plasma cells with large and eccentric nuclei with prominent nucleoli and abundant cytoplasm (H&E stain, ×200). (B) Immunohistochemistry showing tumor cells with diffuse reactivity to cytoplasmic monoclonal kappa-light chain reactivity (×200).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC4499596&req=5

Figure 4: (A) Microscopic examination showing diffuse infiltrates of plasma cells with large and eccentric nuclei with prominent nucleoli and abundant cytoplasm (H&E stain, ×200). (B) Immunohistochemistry showing tumor cells with diffuse reactivity to cytoplasmic monoclonal kappa-light chain reactivity (×200).

Mentions: Percutaneous needle biopsy using ultrasound was performed. Lung ultrasound revealed an ill-defined, hypoechoic subpleural lesion measuring about 5.0 cm×2.7 cm at right paraspinal area of T6-7 level. And microscopic examination showed diffuse infiltrates of polymorphous and asynchronous plasma cells with large and eccentric nuclei, prominent nucleoli, and abundant cytoplasm (Figure 4A). Immunohistochemistry revealed the biopsy was positive for CD138, the cytoplasm was diffusely reactive for monoclonal kappa-light chain (Figure 4B). Based on these findings, the posterior mediastinal mass was diagnosed as a IgG kappa type plasmacytoma.


A Case of Posterior Mediastinal Plasmacytoma Confounded by Community-Acquired Pneumonia.

Heo D, Boo KY, Jwa H, Lee HY, Kim J, Kim ST, Seo HM, Han SH, Maeng YH, Lee JH - Tuberc Respir Dis (Seoul) (2015)

(A) Microscopic examination showing diffuse infiltrates of plasma cells with large and eccentric nuclei with prominent nucleoli and abundant cytoplasm (H&E stain, ×200). (B) Immunohistochemistry showing tumor cells with diffuse reactivity to cytoplasmic monoclonal kappa-light chain reactivity (×200).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4499596&req=5

Figure 4: (A) Microscopic examination showing diffuse infiltrates of plasma cells with large and eccentric nuclei with prominent nucleoli and abundant cytoplasm (H&E stain, ×200). (B) Immunohistochemistry showing tumor cells with diffuse reactivity to cytoplasmic monoclonal kappa-light chain reactivity (×200).
Mentions: Percutaneous needle biopsy using ultrasound was performed. Lung ultrasound revealed an ill-defined, hypoechoic subpleural lesion measuring about 5.0 cm×2.7 cm at right paraspinal area of T6-7 level. And microscopic examination showed diffuse infiltrates of polymorphous and asynchronous plasma cells with large and eccentric nuclei, prominent nucleoli, and abundant cytoplasm (Figure 4A). Immunohistochemistry revealed the biopsy was positive for CD138, the cytoplasm was diffusely reactive for monoclonal kappa-light chain (Figure 4B). Based on these findings, the posterior mediastinal mass was diagnosed as a IgG kappa type plasmacytoma.

Bottom Line: A 67-year-old man recovered after antibiotic treatment for community-acquired pneumonia.Follow-up chest computed tomography (CT) revealed an increase in the extent of the right posterior mediastinal mass that we had considered to be pneumonic consolidations on previous CT scans.Through percutaneous needle biopsy, we diagnosed IgG kappa type extramedullary plasmacytoma of the posterior mediastinum.

View Article: PubMed Central - PubMed

Affiliation: Department of Internal Medicine, Jeju National University Hospital, Jeju National University School of Medicine, Jeju, Korea.

ABSTRACT
Plasmacytomas are extramedullary accumulations of plasma cells originating from soft tissue. Mediastinal plasmacytoma is a rare presentation. A 67-year-old man recovered after antibiotic treatment for community-acquired pneumonia. However, on convalescent chest radiography after 3 months, mass like lesion at the right lower lung field was newly detected. Follow-up chest computed tomography (CT) revealed an increase in the extent of the right posterior mediastinal mass that we had considered to be pneumonic consolidations on previous CT scans. Through percutaneous needle biopsy, we diagnosed IgG kappa type extramedullary plasmacytoma of the posterior mediastinum.

No MeSH data available.


Related in: MedlinePlus