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Vitamin D Status in South Korean Military Personnel with Acute Eosinophilic Pneumonia: A Pilot Study.

Jhun BW, Kim SJ, Kim K, Lee JE, Hong DJ - Tuberc Respir Dis (Seoul) (2015)

Bottom Line: We prospectively compared the serum levels of total 25-hydroxyvitamin D [25(OH)D], 25(OH)D3, and 25(OH)D2 among patients with AEP, pulmonary tuberculosis (PTB), and community-acquired pneumonia (CAP).The difference in the total 25(OH)D levels among patients with AEP, PTB, and CAP was not statistically significant (p=0.230).We have shown that low vitamin D levels are frequently found in patients with AEP and are comparable with those in patients with PTB and CAP.

View Article: PubMed Central - PubMed

Affiliation: Division of Pulmonary and Critical Care Medicine, Department of Medicine, The Armed Forces Capital Hospital, Seongnam, Korea.

ABSTRACT

Background: A relationship between low vitamin D levels and the development or outcomes of respiratory diseases has been identified. However, there is no data on the vitamin D status in patients with acute eosinophilic pneumonia (AEP). We evaluated the vitamin D status in patients with AEP among South Korean military personnel.

Methods: We prospectively compared the serum levels of total 25-hydroxyvitamin D [25(OH)D], 25(OH)D3, and 25(OH)D2 among patients with AEP, pulmonary tuberculosis (PTB), and community-acquired pneumonia (CAP).

Results: In total, 65 patients with respiratory diseases, including AEP (n=24), PTB (n=19), and CAP (n=22), were identified. Of the 24 patients with AEP, 2 (8%) had deficient total 25(OH)D levels (<10 ng/mL), 17 (71%) had insufficient total 25(OH)D levels (≥10 to <30 ng/mL), and only 5 (21%) had sufficient total 25(OH)D levels (≥30 to <100 ng/mL). The difference in the total 25(OH)D levels among patients with AEP, PTB, and CAP was not statistically significant (p=0.230). The median levels of total 25(OH)D, 25(OH)D3, and 25(OH)D2 were 22.84, 22.84, and 0.00 ng/mL, respectively, and no differences in the 25(OH)D level were present among patients with AEP, PTB, and CAP with the exception of the total 25(OH)D level between patients with AEP and PTB (p=0.042).

Conclusion: We have shown that low vitamin D levels are frequently found in patients with AEP and are comparable with those in patients with PTB and CAP.

No MeSH data available.


Related in: MedlinePlus

Comparisons of serum 25(OH)D3 levels among patients with acute eosinophilic pneumonia (AEP), pulmonary tuberculosis (PTB), and community-acquired pneumonia (CAP). NS: not significant.
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Figure 3: Comparisons of serum 25(OH)D3 levels among patients with acute eosinophilic pneumonia (AEP), pulmonary tuberculosis (PTB), and community-acquired pneumonia (CAP). NS: not significant.

Mentions: We also compared the total 25(OH)D (Figure 2), 25(OH)D3 (Figure 3), and 25(OH)D2 (Figure 4) levels among the study patients with AEP, PTB, and CAP. There were no significant differences in the 25(OH)D levels among the study patients, with the exception of the total 25(OH)D level between patients with AEP and PTB (p=0.042) (Figure 2).


Vitamin D Status in South Korean Military Personnel with Acute Eosinophilic Pneumonia: A Pilot Study.

Jhun BW, Kim SJ, Kim K, Lee JE, Hong DJ - Tuberc Respir Dis (Seoul) (2015)

Comparisons of serum 25(OH)D3 levels among patients with acute eosinophilic pneumonia (AEP), pulmonary tuberculosis (PTB), and community-acquired pneumonia (CAP). NS: not significant.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4499591&req=5

Figure 3: Comparisons of serum 25(OH)D3 levels among patients with acute eosinophilic pneumonia (AEP), pulmonary tuberculosis (PTB), and community-acquired pneumonia (CAP). NS: not significant.
Mentions: We also compared the total 25(OH)D (Figure 2), 25(OH)D3 (Figure 3), and 25(OH)D2 (Figure 4) levels among the study patients with AEP, PTB, and CAP. There were no significant differences in the 25(OH)D levels among the study patients, with the exception of the total 25(OH)D level between patients with AEP and PTB (p=0.042) (Figure 2).

Bottom Line: We prospectively compared the serum levels of total 25-hydroxyvitamin D [25(OH)D], 25(OH)D3, and 25(OH)D2 among patients with AEP, pulmonary tuberculosis (PTB), and community-acquired pneumonia (CAP).The difference in the total 25(OH)D levels among patients with AEP, PTB, and CAP was not statistically significant (p=0.230).We have shown that low vitamin D levels are frequently found in patients with AEP and are comparable with those in patients with PTB and CAP.

View Article: PubMed Central - PubMed

Affiliation: Division of Pulmonary and Critical Care Medicine, Department of Medicine, The Armed Forces Capital Hospital, Seongnam, Korea.

ABSTRACT

Background: A relationship between low vitamin D levels and the development or outcomes of respiratory diseases has been identified. However, there is no data on the vitamin D status in patients with acute eosinophilic pneumonia (AEP). We evaluated the vitamin D status in patients with AEP among South Korean military personnel.

Methods: We prospectively compared the serum levels of total 25-hydroxyvitamin D [25(OH)D], 25(OH)D3, and 25(OH)D2 among patients with AEP, pulmonary tuberculosis (PTB), and community-acquired pneumonia (CAP).

Results: In total, 65 patients with respiratory diseases, including AEP (n=24), PTB (n=19), and CAP (n=22), were identified. Of the 24 patients with AEP, 2 (8%) had deficient total 25(OH)D levels (<10 ng/mL), 17 (71%) had insufficient total 25(OH)D levels (≥10 to <30 ng/mL), and only 5 (21%) had sufficient total 25(OH)D levels (≥30 to <100 ng/mL). The difference in the total 25(OH)D levels among patients with AEP, PTB, and CAP was not statistically significant (p=0.230). The median levels of total 25(OH)D, 25(OH)D3, and 25(OH)D2 were 22.84, 22.84, and 0.00 ng/mL, respectively, and no differences in the 25(OH)D level were present among patients with AEP, PTB, and CAP with the exception of the total 25(OH)D level between patients with AEP and PTB (p=0.042).

Conclusion: We have shown that low vitamin D levels are frequently found in patients with AEP and are comparable with those in patients with PTB and CAP.

No MeSH data available.


Related in: MedlinePlus