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Endiandric Acid Derivatives and Other Constituents of Plants from the Genera Beilschmiedia and Endiandra (Lauraceae).

Lenta BN, Chouna JR, Nkeng-Efouet PA, Sewald N - Biomolecules (2015)

Bottom Line: They are the only source of bioactive endiandric acid derivatives.Noteworthy is that their biosynthesis contains two consecutive non-enzymatic electrocyclic reactions.This review compiles information on the structures of the compounds described between January 1960 and March 2015, their biological activities and information on endiandric acid biosynthesis, with 104 references being cited.

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ABSTRACT
Plants of the Lauraceae family are widely used in traditional medicine and are sources of various classes of secondary metabolites. Two genera of this family, Beilschmiedia and Endiandra, have been the subject of numerous investigations over the past decades because of their application in traditional medicine. They are the only source of bioactive endiandric acid derivatives. Noteworthy is that their biosynthesis contains two consecutive non-enzymatic electrocyclic reactions. Several interesting biological activities for this specific class of secondary metabolites and other constituents of the two genera have been reported, including antimicrobial, enzymes inhibitory and cytotoxic properties. This review compiles information on the structures of the compounds described between January 1960 and March 2015, their biological activities and information on endiandric acid biosynthesis, with 104 references being cited.

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General biosynthesis scheme of polyketides.
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biomolecules-05-00910-f003: General biosynthesis scheme of polyketides.


Endiandric Acid Derivatives and Other Constituents of Plants from the Genera Beilschmiedia and Endiandra (Lauraceae).

Lenta BN, Chouna JR, Nkeng-Efouet PA, Sewald N - Biomolecules (2015)

General biosynthesis scheme of polyketides.
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4496702&req=5

biomolecules-05-00910-f003: General biosynthesis scheme of polyketides.
Bottom Line: They are the only source of bioactive endiandric acid derivatives.Noteworthy is that their biosynthesis contains two consecutive non-enzymatic electrocyclic reactions.This review compiles information on the structures of the compounds described between January 1960 and March 2015, their biological activities and information on endiandric acid biosynthesis, with 104 references being cited.

View Article: PubMed Central - PubMed

ABSTRACT
Plants of the Lauraceae family are widely used in traditional medicine and are sources of various classes of secondary metabolites. Two genera of this family, Beilschmiedia and Endiandra, have been the subject of numerous investigations over the past decades because of their application in traditional medicine. They are the only source of bioactive endiandric acid derivatives. Noteworthy is that their biosynthesis contains two consecutive non-enzymatic electrocyclic reactions. Several interesting biological activities for this specific class of secondary metabolites and other constituents of the two genera have been reported, including antimicrobial, enzymes inhibitory and cytotoxic properties. This review compiles information on the structures of the compounds described between January 1960 and March 2015, their biological activities and information on endiandric acid biosynthesis, with 104 references being cited.

Show MeSH