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Rising trend in vitamin D status from 1993 to 2013: dual concerns for the future.

McKenna MJ, Murray BF, O'Keane M, Kilbane MT - Endocr Connect (2015)

Bottom Line: We retrieved all results of serum 25OHD from 1993 to 2013 (n=69 012) that was trimmed to one sample per person (n=43 782).The yearly average 25OHD increased from 36.1 nmol/l in 1993 to 57.3 nmol/l in 2013.The ARIMA model was a good fit for the 25OHD time series; it forecasted monthly average 25OHD up to the end of 2016 with a positive stationary R(2) of 0.377.

View Article: PubMed Central - PubMed

Affiliation: Metabolism LaboratoryDepartment of EndocrinologySt Vincent's University Hospital, Elm Park, Dublin 4, IrelandSchool of Medicine and Medical SciencesUniversity College Dublin, Belfield, Dublin 4, Ireland Metabolism LaboratoryDepartment of EndocrinologySt Vincent's University Hospital, Elm Park, Dublin 4, IrelandSchool of Medicine and Medical SciencesUniversity College Dublin, Belfield, Dublin 4, Ireland Metabolism LaboratoryDepartment of EndocrinologySt Vincent's University Hospital, Elm Park, Dublin 4, IrelandSchool of Medicine and Medical SciencesUniversity College Dublin, Belfield, Dublin 4, Ireland mjmckenn@iol.ie.

No MeSH data available.


Related in: MedlinePlus

Scattergram of monthly average 25OHD since 1993 (n=248) (upper panel) and scattergram of change in yearly average 25OHD compared to baseline of 1993 (n=21) (lower panel).
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fig2: Scattergram of monthly average 25OHD since 1993 (n=248) (upper panel) and scattergram of change in yearly average 25OHD compared to baseline of 1993 (n=21) (lower panel).

Mentions: The scattergrams of the monthly average 25OHD and the difference in yearly average 25OHD between 1993 and 2013 displayed an upward trend (Fig. 2). The regression line for monthly-average 25OHD was as follows: 25OHD (nmol/l)=month×0.057+43 (nmol/l), r=0.428, P<0.001. The increase in the average 25OHD level per 1 month was 0.057 nmol/l (0.023 ng/ml), implying an increase of 0.68 nmol/l (0.28 ng/ml) per year over the last 20 years. The regression line for the change in yearly-average 25OHD was as follows: Δ25OHD (nmol/l)=year×0.68 (nmol/l), r=0.825, P<0.001 (Fig. 2).


Rising trend in vitamin D status from 1993 to 2013: dual concerns for the future.

McKenna MJ, Murray BF, O'Keane M, Kilbane MT - Endocr Connect (2015)

Scattergram of monthly average 25OHD since 1993 (n=248) (upper panel) and scattergram of change in yearly average 25OHD compared to baseline of 1993 (n=21) (lower panel).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4496526&req=5

fig2: Scattergram of monthly average 25OHD since 1993 (n=248) (upper panel) and scattergram of change in yearly average 25OHD compared to baseline of 1993 (n=21) (lower panel).
Mentions: The scattergrams of the monthly average 25OHD and the difference in yearly average 25OHD between 1993 and 2013 displayed an upward trend (Fig. 2). The regression line for monthly-average 25OHD was as follows: 25OHD (nmol/l)=month×0.057+43 (nmol/l), r=0.428, P<0.001. The increase in the average 25OHD level per 1 month was 0.057 nmol/l (0.023 ng/ml), implying an increase of 0.68 nmol/l (0.28 ng/ml) per year over the last 20 years. The regression line for the change in yearly-average 25OHD was as follows: Δ25OHD (nmol/l)=year×0.68 (nmol/l), r=0.825, P<0.001 (Fig. 2).

Bottom Line: We retrieved all results of serum 25OHD from 1993 to 2013 (n=69 012) that was trimmed to one sample per person (n=43 782).The yearly average 25OHD increased from 36.1 nmol/l in 1993 to 57.3 nmol/l in 2013.The ARIMA model was a good fit for the 25OHD time series; it forecasted monthly average 25OHD up to the end of 2016 with a positive stationary R(2) of 0.377.

View Article: PubMed Central - PubMed

Affiliation: Metabolism LaboratoryDepartment of EndocrinologySt Vincent's University Hospital, Elm Park, Dublin 4, IrelandSchool of Medicine and Medical SciencesUniversity College Dublin, Belfield, Dublin 4, Ireland Metabolism LaboratoryDepartment of EndocrinologySt Vincent's University Hospital, Elm Park, Dublin 4, IrelandSchool of Medicine and Medical SciencesUniversity College Dublin, Belfield, Dublin 4, Ireland Metabolism LaboratoryDepartment of EndocrinologySt Vincent's University Hospital, Elm Park, Dublin 4, IrelandSchool of Medicine and Medical SciencesUniversity College Dublin, Belfield, Dublin 4, Ireland mjmckenn@iol.ie.

No MeSH data available.


Related in: MedlinePlus