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Churg-Strauss Syndrome as an Unusual Cause of Dysphagia: Case Report.

Park J, Im S, Moon SJ, Park GY, Jang Y, Kim Y - Ann Rehabil Med (2015)

Bottom Line: Biopsy of the nasal cavity showed extravascular eosinophilic infiltration.All these findings suggested a rare form of Churg-Strauss syndrome involving multiple lower cranial nerves.Dysphagia improved after steroid therapy.

View Article: PubMed Central - PubMed

Affiliation: Department of Rehabilitation Medicine, Bucheon St. Mary's Hospital, The Catholic University of Korea College of Medicine, Bucheon, Korea.

ABSTRACT
Systemic vasculitis is a rare disease, and the diagnosis is very difficult when patient shows atypical symptoms. We experienced an unusual case of dysphagia caused by Churg-Strauss syndrome with lower cranial nerve involvement. A 74-year-old man, with a past history of sinusitis, asthma, and hearing deficiency, was admitted to our department for evaluation of dysphagia. He also complained of recurrent bleeding of nasal cavities and esophagus. Brain magnetic resonance imaging did not show definite abnormality, and electrophysiologic findings were suggestive of mononeuritis multiplex. Dysphagia had not improved after conventional therapy. Biopsy of the nasal cavity showed extravascular eosinophilic infiltration. All these findings suggested a rare form of Churg-Strauss syndrome involving multiple lower cranial nerves. Dysphagia improved after steroid therapy.

No MeSH data available.


Related in: MedlinePlus

Biopsy findings. Nasal biopsy (A) and esophageal biopsy (B) show extravascular eosinophilic infiltration (H&E, ×400).
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Figure 4: Biopsy findings. Nasal biopsy (A) and esophageal biopsy (B) show extravascular eosinophilic infiltration (H&E, ×400).

Mentions: The patient's symptoms did not show any change after several weeks of dysphagia therapy. Despite these multiple signs, no definite neurodegenerative disease could be attributed to the patient's signs. To exclude systemic disorders, he was referred to the Department of Ophthalmology for evaluation and was diagnosed with uveitis. Biopsy of nasal cavity and esophagus showed vasculitis involving small sized blood vessels with extravascular eosinophilic infiltration (Fig. 4A, 4B).


Churg-Strauss Syndrome as an Unusual Cause of Dysphagia: Case Report.

Park J, Im S, Moon SJ, Park GY, Jang Y, Kim Y - Ann Rehabil Med (2015)

Biopsy findings. Nasal biopsy (A) and esophageal biopsy (B) show extravascular eosinophilic infiltration (H&E, ×400).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4496520&req=5

Figure 4: Biopsy findings. Nasal biopsy (A) and esophageal biopsy (B) show extravascular eosinophilic infiltration (H&E, ×400).
Mentions: The patient's symptoms did not show any change after several weeks of dysphagia therapy. Despite these multiple signs, no definite neurodegenerative disease could be attributed to the patient's signs. To exclude systemic disorders, he was referred to the Department of Ophthalmology for evaluation and was diagnosed with uveitis. Biopsy of nasal cavity and esophagus showed vasculitis involving small sized blood vessels with extravascular eosinophilic infiltration (Fig. 4A, 4B).

Bottom Line: Biopsy of the nasal cavity showed extravascular eosinophilic infiltration.All these findings suggested a rare form of Churg-Strauss syndrome involving multiple lower cranial nerves.Dysphagia improved after steroid therapy.

View Article: PubMed Central - PubMed

Affiliation: Department of Rehabilitation Medicine, Bucheon St. Mary's Hospital, The Catholic University of Korea College of Medicine, Bucheon, Korea.

ABSTRACT
Systemic vasculitis is a rare disease, and the diagnosis is very difficult when patient shows atypical symptoms. We experienced an unusual case of dysphagia caused by Churg-Strauss syndrome with lower cranial nerve involvement. A 74-year-old man, with a past history of sinusitis, asthma, and hearing deficiency, was admitted to our department for evaluation of dysphagia. He also complained of recurrent bleeding of nasal cavities and esophagus. Brain magnetic resonance imaging did not show definite abnormality, and electrophysiologic findings were suggestive of mononeuritis multiplex. Dysphagia had not improved after conventional therapy. Biopsy of the nasal cavity showed extravascular eosinophilic infiltration. All these findings suggested a rare form of Churg-Strauss syndrome involving multiple lower cranial nerves. Dysphagia improved after steroid therapy.

No MeSH data available.


Related in: MedlinePlus