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A Surgically Resected Large Sarcomatoid Carcinoma of the Jejunum: A Case Report and Literature Review.

Lee HM, Cho MS, Kim YI - J Gastric Cancer (2015)

Bottom Line: Both lobes of the liver had multiple metastases.On immunohistochemical analysis, the tumor was positive for epithelial and mesenchymal markers.The patient died from rapid progression of the liver metastases 6 weeks after the surgery.

View Article: PubMed Central - PubMed

Affiliation: Department of Surgery, Ewha Womans University School of Medicine, Seoul, Korea.

ABSTRACT
Sarcomatoid carcinoma of the small intestine is rare, and only 30 cases have been reported to date. This disease generally exhibits a very poor prognosis. Here we report the case of a 67-year-old man with a sarcomatoid carcinoma in the jejunum, who was hospitalized for diarrhea, fever, nausea, and vomiting. The tumor was located at the jejunum and had a large round shape with geographic necrosis. It involved the entire wall of the small intestine and had directly invaded the neighboring sigmoid colon. Both lobes of the liver had multiple metastases. The patient underwent surgical resection of the jejunum. On immunohistochemical analysis, the tumor was positive for epithelial and mesenchymal markers. The patient died from rapid progression of the liver metastases 6 weeks after the surgery.

No MeSH data available.


Related in: MedlinePlus

The tumor was composed of ovoid to anaplastic cells forming solid sheets (H&E, ×400).
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Figure 1: The tumor was composed of ovoid to anaplastic cells forming solid sheets (H&E, ×400).

Mentions: Microscopically, the tumor was composed of two cell components, namely ovoid to anaplastic tumor cells and spindle malignant cells. The ovoid to anaplastic tumor cells forming solid sheets without intracytoplasmic mucin globules represented the carcinomatous portion of the tumor (Fig. 1), whereas the spindle malignant cells in a fascicular arrangement represented the sarcomatous portion of the tumor (Fig. 2). The two components were intermixed, and both cell types showed vesicular chromatin, prominent nucleoli, and eosinophilic cytoplasm.


A Surgically Resected Large Sarcomatoid Carcinoma of the Jejunum: A Case Report and Literature Review.

Lee HM, Cho MS, Kim YI - J Gastric Cancer (2015)

The tumor was composed of ovoid to anaplastic cells forming solid sheets (H&E, ×400).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4496442&req=5

Figure 1: The tumor was composed of ovoid to anaplastic cells forming solid sheets (H&E, ×400).
Mentions: Microscopically, the tumor was composed of two cell components, namely ovoid to anaplastic tumor cells and spindle malignant cells. The ovoid to anaplastic tumor cells forming solid sheets without intracytoplasmic mucin globules represented the carcinomatous portion of the tumor (Fig. 1), whereas the spindle malignant cells in a fascicular arrangement represented the sarcomatous portion of the tumor (Fig. 2). The two components were intermixed, and both cell types showed vesicular chromatin, prominent nucleoli, and eosinophilic cytoplasm.

Bottom Line: Both lobes of the liver had multiple metastases.On immunohistochemical analysis, the tumor was positive for epithelial and mesenchymal markers.The patient died from rapid progression of the liver metastases 6 weeks after the surgery.

View Article: PubMed Central - PubMed

Affiliation: Department of Surgery, Ewha Womans University School of Medicine, Seoul, Korea.

ABSTRACT
Sarcomatoid carcinoma of the small intestine is rare, and only 30 cases have been reported to date. This disease generally exhibits a very poor prognosis. Here we report the case of a 67-year-old man with a sarcomatoid carcinoma in the jejunum, who was hospitalized for diarrhea, fever, nausea, and vomiting. The tumor was located at the jejunum and had a large round shape with geographic necrosis. It involved the entire wall of the small intestine and had directly invaded the neighboring sigmoid colon. Both lobes of the liver had multiple metastases. The patient underwent surgical resection of the jejunum. On immunohistochemical analysis, the tumor was positive for epithelial and mesenchymal markers. The patient died from rapid progression of the liver metastases 6 weeks after the surgery.

No MeSH data available.


Related in: MedlinePlus