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TM-MC: a database of medicinal materials and chemical compounds in Northeast Asian traditional medicine.

Kim SK, Nam S, Jang H, Kim A, Lee JJ - BMC Complement Altern Med (2015)

Bottom Line: In traditional medicine, there has been a great deal of research on the effects exhibited by medicinal materials.To study the effects, resources that can systematically describe the chemical compounds in medicinal materials are necessary.Researchers can easily check relevant information through the links to articles.

View Article: PubMed Central - PubMed

Affiliation: Mibyeong Research Center, Korea Institute of Oriental Medicine, Daejeon, South Korea.

ABSTRACT

Background: In traditional medicine, there has been a great deal of research on the effects exhibited by medicinal materials. To study the effects, resources that can systematically describe the chemical compounds in medicinal materials are necessary. In recent years, numerous databases on medicinal materials and constituent compounds have been constructed. However, because these databases provide differing information and the sources of such information are unclear or difficult to verify, it is difficult to decide which database to use. Moreover, there is much overlapping information. The aim of this study was to construct a database of medicinal materials and chemical compounds in Northeast Asian traditional medicine (TM-MC), for which medicinal materials are listed in the Korean, Chinese, and Japanese pharmacopoeias and information on the compound names of medicinal materials can easily be confirmed online.

Description: To provide information on the chemical compounds of medicinal materials, chromatography articles from MEDLINE and PubMed Central were searched. After chemical compounds of medicinal materials were extracted by manually investigating the full-text of articles, a database of information on about 14,000 compounds from 536 medicinal materials was built. The database also provides links to the articles from which each medicinal material and chemical compound were extracted.

Conclusion: TM-MC database provides information on medicinal materials and their chemical compounds from chromatography articles in MEDLINE and PubMed Central. Researchers can easily check relevant information through the links to articles.

No MeSH data available.


Result of search for the keyword “Ephedrae Herba”
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Related In: Results  -  Collection

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Fig2: Result of search for the keyword “Ephedrae Herba”

Mentions: In addition to viewing lists of all the medicinal materials and chemical compounds, users can also directly search the information using the “Search” menu. When search terms are entered in the search field at the top, a maximum of ten medicinal materials and chemical compounds that include the search terms entered are recommended, thus making searching convenient. The search results are shown at the bottom, with the medicinal materials and chemical compounds separated by tabs, together with the number of search results. Figure 2 provides an example of a search for a medicinal material called “Ephedra herba”. The name of the medicinal material is shown in the form of the “Latin Name (common name), [Korean name, Chinese name]” in the medicinal material tab, and pictures, scientific names, effects, treatments, and constituent compounds are under the name of the medicinal material. Additional details such as scientific names and information on effects and treatments comes from the medicinal material ontology built by Jang et al. [27]. Compared to other databases [1, 2, 6–8, 14, 15, 17], this additional information is not yet sufficient, such that users might need to search other databases at the present time. In the future, we will update our database to provide more comprehensive information on medicinal materials. A link to the NCBI Taxonomy (http://www.ncbi.nlm.nih.gov/taxonomy) is next to the scientific name, thus allowing users to obtain additional information on the plant species of the medicinal material. When a chemical compound is clicked, the name of that compound is searched again. Next to the name of the chemical compound, links to compounds in PubChem and ChemSpider, and to PubMed articles from which both the medicinal material and its chemical compound have been extracted are displayed.Fig. 2


TM-MC: a database of medicinal materials and chemical compounds in Northeast Asian traditional medicine.

Kim SK, Nam S, Jang H, Kim A, Lee JJ - BMC Complement Altern Med (2015)

Result of search for the keyword “Ephedrae Herba”
© Copyright Policy - open-access
Related In: Results  -  Collection

License 1 - License 2
Show All Figures
getmorefigures.php?uid=PMC4495939&req=5

Fig2: Result of search for the keyword “Ephedrae Herba”
Mentions: In addition to viewing lists of all the medicinal materials and chemical compounds, users can also directly search the information using the “Search” menu. When search terms are entered in the search field at the top, a maximum of ten medicinal materials and chemical compounds that include the search terms entered are recommended, thus making searching convenient. The search results are shown at the bottom, with the medicinal materials and chemical compounds separated by tabs, together with the number of search results. Figure 2 provides an example of a search for a medicinal material called “Ephedra herba”. The name of the medicinal material is shown in the form of the “Latin Name (common name), [Korean name, Chinese name]” in the medicinal material tab, and pictures, scientific names, effects, treatments, and constituent compounds are under the name of the medicinal material. Additional details such as scientific names and information on effects and treatments comes from the medicinal material ontology built by Jang et al. [27]. Compared to other databases [1, 2, 6–8, 14, 15, 17], this additional information is not yet sufficient, such that users might need to search other databases at the present time. In the future, we will update our database to provide more comprehensive information on medicinal materials. A link to the NCBI Taxonomy (http://www.ncbi.nlm.nih.gov/taxonomy) is next to the scientific name, thus allowing users to obtain additional information on the plant species of the medicinal material. When a chemical compound is clicked, the name of that compound is searched again. Next to the name of the chemical compound, links to compounds in PubChem and ChemSpider, and to PubMed articles from which both the medicinal material and its chemical compound have been extracted are displayed.Fig. 2

Bottom Line: In traditional medicine, there has been a great deal of research on the effects exhibited by medicinal materials.To study the effects, resources that can systematically describe the chemical compounds in medicinal materials are necessary.Researchers can easily check relevant information through the links to articles.

View Article: PubMed Central - PubMed

Affiliation: Mibyeong Research Center, Korea Institute of Oriental Medicine, Daejeon, South Korea.

ABSTRACT

Background: In traditional medicine, there has been a great deal of research on the effects exhibited by medicinal materials. To study the effects, resources that can systematically describe the chemical compounds in medicinal materials are necessary. In recent years, numerous databases on medicinal materials and constituent compounds have been constructed. However, because these databases provide differing information and the sources of such information are unclear or difficult to verify, it is difficult to decide which database to use. Moreover, there is much overlapping information. The aim of this study was to construct a database of medicinal materials and chemical compounds in Northeast Asian traditional medicine (TM-MC), for which medicinal materials are listed in the Korean, Chinese, and Japanese pharmacopoeias and information on the compound names of medicinal materials can easily be confirmed online.

Description: To provide information on the chemical compounds of medicinal materials, chromatography articles from MEDLINE and PubMed Central were searched. After chemical compounds of medicinal materials were extracted by manually investigating the full-text of articles, a database of information on about 14,000 compounds from 536 medicinal materials was built. The database also provides links to the articles from which each medicinal material and chemical compound were extracted.

Conclusion: TM-MC database provides information on medicinal materials and their chemical compounds from chromatography articles in MEDLINE and PubMed Central. Researchers can easily check relevant information through the links to articles.

No MeSH data available.