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Serological profile of foot-and-mouth disease in wildlife populations of West and Central Africa with special reference to Syncerus caffer subspecies.

Di Nardo A, Libeau G, Chardonnet B, Chardonnet P, Kock RA, Parekh K, Hamblin P, Li Y, Parida S, Sumption KJ - Vet. Res. (2015)

Bottom Line: Different levels of exposure to the FMDV resulted for each of the buffalo subspecies sampled (p = 0.031): 68.4%, 50.0% and 0% for Nile Buffalo, West African Buffalo and African Forest Buffalo, respectively.The characterisation of the FMDV serotypes tested for buffalo found presence of antibodies against all the six FMDV serotypes tested, although high estimates for type O and SAT 3 were reported for Central Africa.The results confirmed that FMDV circulates in wild ruminants populating both West and Central Africa rangelands and in particular in buffalo, also suggesting that multiple FMDV serotypes might be involved with type O, SAT 2 and SAT 1 being dominant.

View Article: PubMed Central - PubMed

Affiliation: Institute of Biodiversity, Animal Health and Comparative Medicine, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom. a.di-nardo.1@research.gla.ac.uk.

ABSTRACT
The role which West and Central African wildlife populations might play in the transmission dynamics of FMD is not known nor have studies been performed in order to assess the distribution and prevalence of FMD in wild animal species inhabiting those specific regions of Africa. This study reports the FMD serological profile extracted from samples (n = 696) collected from wildlife of West and Central Africa between 1999 and 2003. An overall prevalence of FMDV NSP reactive sera of 31.0% (216/696) was estimated, where a significant difference in seropositivity (p = 0.000) was reported for buffalo (64.8%) as opposed to other wild animal species tested (17.8%). Different levels of exposure to the FMDV resulted for each of the buffalo subspecies sampled (p = 0.031): 68.4%, 50.0% and 0% for Nile Buffalo, West African Buffalo and African Forest Buffalo, respectively. The characterisation of the FMDV serotypes tested for buffalo found presence of antibodies against all the six FMDV serotypes tested, although high estimates for type O and SAT 3 were reported for Central Africa. Different patterns of reaction to the six FMDV serotypes tested were recorded, from sera only positive for a single serotype to multiple reactivities. The results confirmed that FMDV circulates in wild ruminants populating both West and Central Africa rangelands and in particular in buffalo, also suggesting that multiple FMDV serotypes might be involved with type O, SAT 2 and SAT 1 being dominant. Differences in serotype and spill-over risk between wildlife and livestock likely reflect regional geography, historical circulation and differing trade and livestock systems.

No MeSH data available.


Related in: MedlinePlus

Geographical locations of the wildlife samples selected by species. Distributional extents of buffalo subspecies of the Syncerus genus sourced and adapted from [68].
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Fig1: Geographical locations of the wildlife samples selected by species. Distributional extents of buffalo subspecies of the Syncerus genus sourced and adapted from [68].

Mentions: The study was undertaken on serum samples collected from wild ruminants and pigs species during the African Wildlife Veterinary Project [24], as part of the Pan-African Rinderpest Campaign (PARC) and the subsequent programme for the Pan-African Control of Epizootics (PACE) implemented in 34 countries across the African continent between 1986 and 2007. Wildlife species and sampling sites were selected at the time according to susceptibility to the Rinderpest (RP) virus, population biology (i.e. richness, gregarious behaviour, and seasonal movements), interface between livestock and wildlife, and their availability for veterinary interventions. Sampling was performed using purposive sampling by immobilisation, opportunistic sampling by cropping and/or hunting and during field investigations of reported episodes of disease and mortality. From the whole collection stored at the Centre de Coopération Internationale en Recherche Agronomique pour le Développement (CIRAD), Montpellier – France, 696 sera collected between 1999 and 2003 were selected as representative of wildlife populations present in West and Central Africa (Table 1; Figure 1). In addition, further 19 samples collected from cattle within the transfrontier area of the Central African Republic and Chad were included for comparative purpose. Extracted aliquots were sent to The Pirbright Institute, Pirbright – United Kingdom (UK), for diagnostic testing.Table 1


Serological profile of foot-and-mouth disease in wildlife populations of West and Central Africa with special reference to Syncerus caffer subspecies.

Di Nardo A, Libeau G, Chardonnet B, Chardonnet P, Kock RA, Parekh K, Hamblin P, Li Y, Parida S, Sumption KJ - Vet. Res. (2015)

Geographical locations of the wildlife samples selected by species. Distributional extents of buffalo subspecies of the Syncerus genus sourced and adapted from [68].
© Copyright Policy - open-access
Related In: Results  -  Collection

License 1 - License 2
Show All Figures
getmorefigures.php?uid=PMC4495843&req=5

Fig1: Geographical locations of the wildlife samples selected by species. Distributional extents of buffalo subspecies of the Syncerus genus sourced and adapted from [68].
Mentions: The study was undertaken on serum samples collected from wild ruminants and pigs species during the African Wildlife Veterinary Project [24], as part of the Pan-African Rinderpest Campaign (PARC) and the subsequent programme for the Pan-African Control of Epizootics (PACE) implemented in 34 countries across the African continent between 1986 and 2007. Wildlife species and sampling sites were selected at the time according to susceptibility to the Rinderpest (RP) virus, population biology (i.e. richness, gregarious behaviour, and seasonal movements), interface between livestock and wildlife, and their availability for veterinary interventions. Sampling was performed using purposive sampling by immobilisation, opportunistic sampling by cropping and/or hunting and during field investigations of reported episodes of disease and mortality. From the whole collection stored at the Centre de Coopération Internationale en Recherche Agronomique pour le Développement (CIRAD), Montpellier – France, 696 sera collected between 1999 and 2003 were selected as representative of wildlife populations present in West and Central Africa (Table 1; Figure 1). In addition, further 19 samples collected from cattle within the transfrontier area of the Central African Republic and Chad were included for comparative purpose. Extracted aliquots were sent to The Pirbright Institute, Pirbright – United Kingdom (UK), for diagnostic testing.Table 1

Bottom Line: Different levels of exposure to the FMDV resulted for each of the buffalo subspecies sampled (p = 0.031): 68.4%, 50.0% and 0% for Nile Buffalo, West African Buffalo and African Forest Buffalo, respectively.The characterisation of the FMDV serotypes tested for buffalo found presence of antibodies against all the six FMDV serotypes tested, although high estimates for type O and SAT 3 were reported for Central Africa.The results confirmed that FMDV circulates in wild ruminants populating both West and Central Africa rangelands and in particular in buffalo, also suggesting that multiple FMDV serotypes might be involved with type O, SAT 2 and SAT 1 being dominant.

View Article: PubMed Central - PubMed

Affiliation: Institute of Biodiversity, Animal Health and Comparative Medicine, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom. a.di-nardo.1@research.gla.ac.uk.

ABSTRACT
The role which West and Central African wildlife populations might play in the transmission dynamics of FMD is not known nor have studies been performed in order to assess the distribution and prevalence of FMD in wild animal species inhabiting those specific regions of Africa. This study reports the FMD serological profile extracted from samples (n = 696) collected from wildlife of West and Central Africa between 1999 and 2003. An overall prevalence of FMDV NSP reactive sera of 31.0% (216/696) was estimated, where a significant difference in seropositivity (p = 0.000) was reported for buffalo (64.8%) as opposed to other wild animal species tested (17.8%). Different levels of exposure to the FMDV resulted for each of the buffalo subspecies sampled (p = 0.031): 68.4%, 50.0% and 0% for Nile Buffalo, West African Buffalo and African Forest Buffalo, respectively. The characterisation of the FMDV serotypes tested for buffalo found presence of antibodies against all the six FMDV serotypes tested, although high estimates for type O and SAT 3 were reported for Central Africa. Different patterns of reaction to the six FMDV serotypes tested were recorded, from sera only positive for a single serotype to multiple reactivities. The results confirmed that FMDV circulates in wild ruminants populating both West and Central Africa rangelands and in particular in buffalo, also suggesting that multiple FMDV serotypes might be involved with type O, SAT 2 and SAT 1 being dominant. Differences in serotype and spill-over risk between wildlife and livestock likely reflect regional geography, historical circulation and differing trade and livestock systems.

No MeSH data available.


Related in: MedlinePlus