High-resolution functional MRI at 3 T: 3D/2D echo-planar imaging with optimized physiological noise correction.
Bottom Line: We extended image-based physiological noise correction from two-dimensional EPI to multishot three-dimensional EPI.The physiological noise correction increased the sensitivity significantly, can be easily applied, and requires simple recordings of pulse and respiration only.The combination of three-dimensional EPI with physiological noise correction provides exceptional sensitivity for 1.5 mm high-resolution fMRI at 3 T, increasing the temporal signal-to-noise ratio by more than 25% compared to two-dimensional EPI.
Affiliation: Wellcome Trust Centre for Neuroimaging, Department of Brain Repair and Rehabilitation, UCL Institute of Neurology, University College London, London, United Kingdom. firstname.lastname@example.orgShow MeSH
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Mentions: Figure 3a and b shows subject-averaged tSNR maps in Montreal Neurological Institute (MNI) space for the 2D and 3D EPI acquisitions following physiological correction. Higher tSNR values were found for 3D EPI over most brain regions and tissue types. Figure 3c and d shows the increase in tSNR due to physiological correction for 2D and 3D EPI. Figure 3e and f shows comparisons of the tSNR obtained from the 2D and 3D EPI acquisitions before and after physiological correction.
Affiliation: Wellcome Trust Centre for Neuroimaging, Department of Brain Repair and Rehabilitation, UCL Institute of Neurology, University College London, London, United Kingdom. email@example.com