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Prevalence and factors associated with scleral hyaline plaque: clinical study of older adults in southeastern Brazil.

Horowitz S, Damasceno N, Damasceno E - Clin Ophthalmol (2015)

Bottom Line: There was a statistically significant association between the presence of hyaline plaques and sex (female), age range (≥70 years old), ethnicity (Caucasian), cataract, moderate to high myopia, systemic arterial hypertension, degenerative arthritis, and osteoporosis (P<0.05).On multivariate binary logistic regression analysis, only female sex, age range (≥70 years), moderate to high myopia, and degenerative arthritis exhibited significant correlation.The most significant factors associated with scleral hyaline plaque were advanced age, female sex, moderate to high myopia, and degenerative arthritis.

View Article: PubMed Central - PubMed

Affiliation: Department of Ophthalmology, Hospital Naval Marcilio Dias, Rio de Janeiro, Brazil.

ABSTRACT

Purpose: To investigate the prevalence of scleral hyaline plaque among older adults in the city of Niterói in southeastern Brazil. A second goal was to assess the correlation between scleral hyaline plaque and several age-related diseases, including eye diseases and systemic diseases.

Methods: The study sample comprised 667 participants who were followed for 15 months. The study had a prospective, longitudinal, observational design that established inclusion and exclusion criteria. The following variables were selected for correlation with scleral hyaline plaque: sex, age, age range, iris color, ethnicity, presence of cataract, moderate to high myopia, age-related macular degeneration (AMD), diabetes mellitus, systemic arterial hypertension, degenerative arthritis, and osteoporosis. These correlations were assessed by means of the χ (2) test and Student's t-test. Multivariate analysis was performed to exclude factors that were potentially associated with aging exclusively but that did not have a direct relationship with hyaline plaque. Binary logistic regression was used to calculate odds ratios, significance, and confidence intervals.

Results: Scleral hyaline plaques were found in 177 patients (17.54%). There was a statistically significant association between the presence of hyaline plaques and sex (female), age range (≥70 years old), ethnicity (Caucasian), cataract, moderate to high myopia, systemic arterial hypertension, degenerative arthritis, and osteoporosis (P<0.05). On multivariate binary logistic regression analysis, only female sex, age range (≥70 years), moderate to high myopia, and degenerative arthritis exhibited significant correlation.

Conclusion: The prevalence of scleral hyaline plaque in the present study was higher than in previous reports in the medical literature. Several age-related diseases exhibited a correlation with scleral hyaline plaque. The most significant factors associated with scleral hyaline plaque were advanced age, female sex, moderate to high myopia, and degenerative arthritis.

No MeSH data available.


Related in: MedlinePlus

Biomicroscopy of anterior segment – scleral hyaline plaque – Incomplete form.
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f2-opth-9-1187: Biomicroscopy of anterior segment – scleral hyaline plaque – Incomplete form.

Mentions: Personal epidemiological data (sex, ethnicity, age, and iris color) as well as information on the participants’ past clinical history and medications used were collected for the study. All of the participants underwent an ophthalmological examination, which included the following components: best-corrected visual acuity, assessed using the Snellen chart; intraocular pressure, measured with a Goldmann tonometer; indirect ophthalmoscopy (Welch Allyn, Inc. Skaneateles Falls, NY, USA); and slit lamp biomicroscopy of the anterior segment. Slit lamp biomicroscopy allowed the analysis of the scleral hyaline plaques and their classification as the complete or incomplete form according to their size and aspect of the scleral surface. Bilateral and symmetric plaques as well as lesions measuring more than 2 mm (Figure 1) were classified as complete plaques. However, bilateral but asymmetric plaques and lesions measuring less than 2 mm were considered incomplete (Figure 2). The evolution of the plaques (increase in size) was assessed during the follow up.


Prevalence and factors associated with scleral hyaline plaque: clinical study of older adults in southeastern Brazil.

Horowitz S, Damasceno N, Damasceno E - Clin Ophthalmol (2015)

Biomicroscopy of anterior segment – scleral hyaline plaque – Incomplete form.
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4494614&req=5

f2-opth-9-1187: Biomicroscopy of anterior segment – scleral hyaline plaque – Incomplete form.
Mentions: Personal epidemiological data (sex, ethnicity, age, and iris color) as well as information on the participants’ past clinical history and medications used were collected for the study. All of the participants underwent an ophthalmological examination, which included the following components: best-corrected visual acuity, assessed using the Snellen chart; intraocular pressure, measured with a Goldmann tonometer; indirect ophthalmoscopy (Welch Allyn, Inc. Skaneateles Falls, NY, USA); and slit lamp biomicroscopy of the anterior segment. Slit lamp biomicroscopy allowed the analysis of the scleral hyaline plaques and their classification as the complete or incomplete form according to their size and aspect of the scleral surface. Bilateral and symmetric plaques as well as lesions measuring more than 2 mm (Figure 1) were classified as complete plaques. However, bilateral but asymmetric plaques and lesions measuring less than 2 mm were considered incomplete (Figure 2). The evolution of the plaques (increase in size) was assessed during the follow up.

Bottom Line: There was a statistically significant association between the presence of hyaline plaques and sex (female), age range (≥70 years old), ethnicity (Caucasian), cataract, moderate to high myopia, systemic arterial hypertension, degenerative arthritis, and osteoporosis (P<0.05).On multivariate binary logistic regression analysis, only female sex, age range (≥70 years), moderate to high myopia, and degenerative arthritis exhibited significant correlation.The most significant factors associated with scleral hyaline plaque were advanced age, female sex, moderate to high myopia, and degenerative arthritis.

View Article: PubMed Central - PubMed

Affiliation: Department of Ophthalmology, Hospital Naval Marcilio Dias, Rio de Janeiro, Brazil.

ABSTRACT

Purpose: To investigate the prevalence of scleral hyaline plaque among older adults in the city of Niterói in southeastern Brazil. A second goal was to assess the correlation between scleral hyaline plaque and several age-related diseases, including eye diseases and systemic diseases.

Methods: The study sample comprised 667 participants who were followed for 15 months. The study had a prospective, longitudinal, observational design that established inclusion and exclusion criteria. The following variables were selected for correlation with scleral hyaline plaque: sex, age, age range, iris color, ethnicity, presence of cataract, moderate to high myopia, age-related macular degeneration (AMD), diabetes mellitus, systemic arterial hypertension, degenerative arthritis, and osteoporosis. These correlations were assessed by means of the χ (2) test and Student's t-test. Multivariate analysis was performed to exclude factors that were potentially associated with aging exclusively but that did not have a direct relationship with hyaline plaque. Binary logistic regression was used to calculate odds ratios, significance, and confidence intervals.

Results: Scleral hyaline plaques were found in 177 patients (17.54%). There was a statistically significant association between the presence of hyaline plaques and sex (female), age range (≥70 years old), ethnicity (Caucasian), cataract, moderate to high myopia, systemic arterial hypertension, degenerative arthritis, and osteoporosis (P<0.05). On multivariate binary logistic regression analysis, only female sex, age range (≥70 years), moderate to high myopia, and degenerative arthritis exhibited significant correlation.

Conclusion: The prevalence of scleral hyaline plaque in the present study was higher than in previous reports in the medical literature. Several age-related diseases exhibited a correlation with scleral hyaline plaque. The most significant factors associated with scleral hyaline plaque were advanced age, female sex, moderate to high myopia, and degenerative arthritis.

No MeSH data available.


Related in: MedlinePlus