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Spontaneous Resolution of Radiotherapy-induced Craniopharyngioma Cyst.

Teo M, Cowie F, Fivey P, St George J - Cureus (2015)

Bottom Line: Craniopharyngioma cyst enlargement after surgery and radiation therapy is often presumed to represent a treatment failure, instigating further management strategies.We present an eight-year-old girl with a small intrasellar residuum post-resection who then developed cystic enlargement post-radiotherapy.With close surveillance, the cyst spontaneously resolved.

View Article: PubMed Central - HTML - PubMed

Affiliation: School of Medicine, Stanford University Medical Center.

ABSTRACT
Craniopharyngioma cyst enlargement after surgery and radiation therapy is often presumed to represent a treatment failure, instigating further management strategies. We present an eight-year-old girl with a small intrasellar residuum post-resection who then developed cystic enlargement post-radiotherapy. With close surveillance, the cyst spontaneously resolved.

No MeSH data available.


Related in: MedlinePlus

Postoperative T1-weighted MRI brain (sagittal view [panel A], coronal view [panel B]) Shows subtotal resection of the craniopharyngioma with only a small intrasellar residuum (arrowhead).
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FIG2: Postoperative T1-weighted MRI brain (sagittal view [panel A], coronal view [panel B]) Shows subtotal resection of the craniopharyngioma with only a small intrasellar residuum (arrowhead).

Mentions: An eight-year-old girl presented with a one-year history of progressive headache and visual loss. MRI showed a large partly cystic, partly solid craniopharyngioma (Figure 1). A craniotomy and subtotal resection were performed with only an intrasellar residuum apparent on postoperative imaging (Figure 2). Her visual function improved and she subsequently received a six-week course of radiotherapy. Several weeks following that treatment, she complained of non-disabling recurrent dull headache, with no deterioration of her visual function. Repeat MRI showed a recurrent cyst (Figure 3). She was kept under close clinical, radiological and ophthalmological surveillance and nine months later, MRI revealed that the craniopharyngioma cyst had spontaneously resolved, leaving only the previously observed sellar residuum (Figure 4).


Spontaneous Resolution of Radiotherapy-induced Craniopharyngioma Cyst.

Teo M, Cowie F, Fivey P, St George J - Cureus (2015)

Postoperative T1-weighted MRI brain (sagittal view [panel A], coronal view [panel B]) Shows subtotal resection of the craniopharyngioma with only a small intrasellar residuum (arrowhead).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4494584&req=5

FIG2: Postoperative T1-weighted MRI brain (sagittal view [panel A], coronal view [panel B]) Shows subtotal resection of the craniopharyngioma with only a small intrasellar residuum (arrowhead).
Mentions: An eight-year-old girl presented with a one-year history of progressive headache and visual loss. MRI showed a large partly cystic, partly solid craniopharyngioma (Figure 1). A craniotomy and subtotal resection were performed with only an intrasellar residuum apparent on postoperative imaging (Figure 2). Her visual function improved and she subsequently received a six-week course of radiotherapy. Several weeks following that treatment, she complained of non-disabling recurrent dull headache, with no deterioration of her visual function. Repeat MRI showed a recurrent cyst (Figure 3). She was kept under close clinical, radiological and ophthalmological surveillance and nine months later, MRI revealed that the craniopharyngioma cyst had spontaneously resolved, leaving only the previously observed sellar residuum (Figure 4).

Bottom Line: Craniopharyngioma cyst enlargement after surgery and radiation therapy is often presumed to represent a treatment failure, instigating further management strategies.We present an eight-year-old girl with a small intrasellar residuum post-resection who then developed cystic enlargement post-radiotherapy.With close surveillance, the cyst spontaneously resolved.

View Article: PubMed Central - HTML - PubMed

Affiliation: School of Medicine, Stanford University Medical Center.

ABSTRACT
Craniopharyngioma cyst enlargement after surgery and radiation therapy is often presumed to represent a treatment failure, instigating further management strategies. We present an eight-year-old girl with a small intrasellar residuum post-resection who then developed cystic enlargement post-radiotherapy. With close surveillance, the cyst spontaneously resolved.

No MeSH data available.


Related in: MedlinePlus