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A Rare Case of Optic Nerve Schwannoma: Case Report and Review of the Literature.

Ramey WL, Arnold SJ, Chiu A, Lemole M - Cureus (2015)

Bottom Line: Additionally, because of its medial position relative to the optic nerve and within the orbital apex, it is the first such case to be resected via an endoscopic endonasal approach.The lesion was subtotally resected because of its adherence and continuity with the optic nerve and the patient's wish to preserve his vision.He was subsequently referred to radiation oncology for external beam radiation therapy.

View Article: PubMed Central - HTML - PubMed

Affiliation: Neurosurgery, University of Arizona.

ABSTRACT

Background and importance: Schwannomas are typically benign tumors of the peripheral nervous system that originate from Schwann cells. It is well known that the optic nerves are myelinated by oligodendrocytes since their cell bodies arise centrally within the lateral geniculate nuclei. Because of this basic cellular anatomy, optic schwannomas should theoretically not exist. It is possible, however, these rare lesions stem from small sympathetic fibers that innervate the vasculature surrounding the optic nerve and its sheath.

Clinical presentation: The patient is a 46-year-old male with a one-year history of progressive right eye blurry vision. To our knowledge, there are only five known reported case of an optic nerve schwannoma. Additionally, because of its medial position relative to the optic nerve and within the orbital apex, it is the first such case to be resected via an endoscopic endonasal approach. The lesion was subtotally resected because of its adherence and continuity with the optic nerve and the patient's wish to preserve his vision. He was subsequently referred to radiation oncology for external beam radiation therapy.

Conclusion: Herein, we discuss the pertinent clinical findings of this rare lesion and review the literature relative to optic nerve and solitary orbital schwannomas.

No MeSH data available.


Related in: MedlinePlus

Postoperative T1-weighted MRI with contrastAxial view demonstrating a roughly stable enhancing schwannoma following decompression and biopsy as pointed out by the white arrow (A). Coronal view with the tumor again highlighted by the white arrow (B).
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FIG3: Postoperative T1-weighted MRI with contrastAxial view demonstrating a roughly stable enhancing schwannoma following decompression and biopsy as pointed out by the white arrow (A). Coronal view with the tumor again highlighted by the white arrow (B).

Mentions: The patient was seen in clinic three months after his procedure and endorsed subjective improvement in his right eye superior quadrants; however, his preoperative visual deficits would return. Postoperative MRI at this time showed an approximately stable lesion compared to preoperatively (Figure 3).


A Rare Case of Optic Nerve Schwannoma: Case Report and Review of the Literature.

Ramey WL, Arnold SJ, Chiu A, Lemole M - Cureus (2015)

Postoperative T1-weighted MRI with contrastAxial view demonstrating a roughly stable enhancing schwannoma following decompression and biopsy as pointed out by the white arrow (A). Coronal view with the tumor again highlighted by the white arrow (B).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4494577&req=5

FIG3: Postoperative T1-weighted MRI with contrastAxial view demonstrating a roughly stable enhancing schwannoma following decompression and biopsy as pointed out by the white arrow (A). Coronal view with the tumor again highlighted by the white arrow (B).
Mentions: The patient was seen in clinic three months after his procedure and endorsed subjective improvement in his right eye superior quadrants; however, his preoperative visual deficits would return. Postoperative MRI at this time showed an approximately stable lesion compared to preoperatively (Figure 3).

Bottom Line: Additionally, because of its medial position relative to the optic nerve and within the orbital apex, it is the first such case to be resected via an endoscopic endonasal approach.The lesion was subtotally resected because of its adherence and continuity with the optic nerve and the patient's wish to preserve his vision.He was subsequently referred to radiation oncology for external beam radiation therapy.

View Article: PubMed Central - HTML - PubMed

Affiliation: Neurosurgery, University of Arizona.

ABSTRACT

Background and importance: Schwannomas are typically benign tumors of the peripheral nervous system that originate from Schwann cells. It is well known that the optic nerves are myelinated by oligodendrocytes since their cell bodies arise centrally within the lateral geniculate nuclei. Because of this basic cellular anatomy, optic schwannomas should theoretically not exist. It is possible, however, these rare lesions stem from small sympathetic fibers that innervate the vasculature surrounding the optic nerve and its sheath.

Clinical presentation: The patient is a 46-year-old male with a one-year history of progressive right eye blurry vision. To our knowledge, there are only five known reported case of an optic nerve schwannoma. Additionally, because of its medial position relative to the optic nerve and within the orbital apex, it is the first such case to be resected via an endoscopic endonasal approach. The lesion was subtotally resected because of its adherence and continuity with the optic nerve and the patient's wish to preserve his vision. He was subsequently referred to radiation oncology for external beam radiation therapy.

Conclusion: Herein, we discuss the pertinent clinical findings of this rare lesion and review the literature relative to optic nerve and solitary orbital schwannomas.

No MeSH data available.


Related in: MedlinePlus