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Anthropomorphic Phantoms for Confirmation of Linear Accelerator-Based Small Animal Irradiation.

Perks JR, Lucero S, Monjazeb AM, Li JJ - Cureus (2015)

Bottom Line: Three dimensional (3D) scanning and printing technology is utilized to create phantom models of mice in order to assess the accuracy of ionizing radiation dosing from a clinical, human-based linear accelerator.Phantoms are designed to simulate a range of research questions, including irradiation of lung tumors and primary subcutaneous or orthotopic tumors for immunotherapy experimentation.The phantoms are used to measure the accuracy of dose delivery and then refine it to within 1% of the prescribed dose.

View Article: PubMed Central - HTML - PubMed

Affiliation: Radiation Oncology, UC Davis Medical Center.

ABSTRACT
Three dimensional (3D) scanning and printing technology is utilized to create phantom models of mice in order to assess the accuracy of ionizing radiation dosing from a clinical, human-based linear accelerator. Phantoms are designed to simulate a range of research questions, including irradiation of lung tumors and primary subcutaneous or orthotopic tumors for immunotherapy experimentation. The phantoms are used to measure the accuracy of dose delivery and then refine it to within 1% of the prescribed dose.

No MeSH data available.


Related in: MedlinePlus

Mice in position for whole body irradiation, under bolus at linac room isocenter (as marked by room lasers)
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FIG2: Mice in position for whole body irradiation, under bolus at linac room isocenter (as marked by room lasers)

Mentions: A 3D-printed mouse with the chamber hole in the center of the body was irradiated in multiple positions under the beam with bolus directly on top. Additionally, the dose inside the phantom mouse was measured when research mice were irradiated in their cage with the bolus material on top, the standard whole body setup. Figure 2 shows the setup for whole body measurements in a standard cage.


Anthropomorphic Phantoms for Confirmation of Linear Accelerator-Based Small Animal Irradiation.

Perks JR, Lucero S, Monjazeb AM, Li JJ - Cureus (2015)

Mice in position for whole body irradiation, under bolus at linac room isocenter (as marked by room lasers)
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4494576&req=5

FIG2: Mice in position for whole body irradiation, under bolus at linac room isocenter (as marked by room lasers)
Mentions: A 3D-printed mouse with the chamber hole in the center of the body was irradiated in multiple positions under the beam with bolus directly on top. Additionally, the dose inside the phantom mouse was measured when research mice were irradiated in their cage with the bolus material on top, the standard whole body setup. Figure 2 shows the setup for whole body measurements in a standard cage.

Bottom Line: Three dimensional (3D) scanning and printing technology is utilized to create phantom models of mice in order to assess the accuracy of ionizing radiation dosing from a clinical, human-based linear accelerator.Phantoms are designed to simulate a range of research questions, including irradiation of lung tumors and primary subcutaneous or orthotopic tumors for immunotherapy experimentation.The phantoms are used to measure the accuracy of dose delivery and then refine it to within 1% of the prescribed dose.

View Article: PubMed Central - HTML - PubMed

Affiliation: Radiation Oncology, UC Davis Medical Center.

ABSTRACT
Three dimensional (3D) scanning and printing technology is utilized to create phantom models of mice in order to assess the accuracy of ionizing radiation dosing from a clinical, human-based linear accelerator. Phantoms are designed to simulate a range of research questions, including irradiation of lung tumors and primary subcutaneous or orthotopic tumors for immunotherapy experimentation. The phantoms are used to measure the accuracy of dose delivery and then refine it to within 1% of the prescribed dose.

No MeSH data available.


Related in: MedlinePlus