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Fetal Magnetic Resonance Imaging of Malformations Associated with Heterotaxy.

Loomba R, Shah PH, Anderson RH - Cureus (2015)

Bottom Line: One such syndrome is so-called "visceral heterotaxy", in which there is typically an isomeric, rather than a lateralized, arrangement of the thoracic and abdominal organs.Typically associated with complex congenital cardiac malformations, heterotaxy can also involve the central nervous system, and produce pulmonary, gastrointestinal, immunologic, and genitourinary malformations.In this review, we discuss how these findings can be demonstrated using fetal MRI.

View Article: PubMed Central - HTML - PubMed

Affiliation: Cardiology Dept., Children's Hospital of Wisconsin.

ABSTRACT
Magnetic resonance imaging (MRI) is increasingly used as an investigation during fetal life, particularly for assessment of intracranial masses, congenital diaphragmatic hernia, myelomeningocele, and abdominal masses. As the number of scans increases, so is the variety of congenital malformations being recognized. It is axiomatic that interpretation of the findings is enhanced when attention is paid to the likely findings in the setting of known syndromes, this information then dictating the need for additional acquisition of images. One such syndrome is so-called "visceral heterotaxy", in which there is typically an isomeric, rather than a lateralized, arrangement of the thoracic and abdominal organs. Typically associated with complex congenital cardiac malformations, heterotaxy can also involve the central nervous system, and produce pulmonary, gastrointestinal, immunologic, and genitourinary malformations. In this review, we discuss how these findings can be demonstrated using fetal MRI.

No MeSH data available.


Related in: MedlinePlus

Bronchial isomerismA coronal T1-weighted image demonstrating bronchial isomerism with bronchial angles consistent with right isomerism. There is also a midline liver noted in this slice.
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FIG10: Bronchial isomerismA coronal T1-weighted image demonstrating bronchial isomerism with bronchial angles consistent with right isomerism. There is also a midline liver noted in this slice.

Mentions: Congenital pulmonary malformations are limited in heterotaxy, but will include isomerism of the bronchi, as revealed by a ratio of bronchial lengths of less than 1.5. Right as opposed to left bronchial isomerism can be determined by assessing the bronchial angles, with angles less than 135 degrees being consistent with left bronchial isomerism, and angles greater than 135 degrees being consistent with right bronchial isomerism (Figures 9-10). The lungs themselves also show isomeric lobation, which is concordant with the bronchial arrangement [25, 43-44].


Fetal Magnetic Resonance Imaging of Malformations Associated with Heterotaxy.

Loomba R, Shah PH, Anderson RH - Cureus (2015)

Bronchial isomerismA coronal T1-weighted image demonstrating bronchial isomerism with bronchial angles consistent with right isomerism. There is also a midline liver noted in this slice.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4494530&req=5

FIG10: Bronchial isomerismA coronal T1-weighted image demonstrating bronchial isomerism with bronchial angles consistent with right isomerism. There is also a midline liver noted in this slice.
Mentions: Congenital pulmonary malformations are limited in heterotaxy, but will include isomerism of the bronchi, as revealed by a ratio of bronchial lengths of less than 1.5. Right as opposed to left bronchial isomerism can be determined by assessing the bronchial angles, with angles less than 135 degrees being consistent with left bronchial isomerism, and angles greater than 135 degrees being consistent with right bronchial isomerism (Figures 9-10). The lungs themselves also show isomeric lobation, which is concordant with the bronchial arrangement [25, 43-44].

Bottom Line: One such syndrome is so-called "visceral heterotaxy", in which there is typically an isomeric, rather than a lateralized, arrangement of the thoracic and abdominal organs.Typically associated with complex congenital cardiac malformations, heterotaxy can also involve the central nervous system, and produce pulmonary, gastrointestinal, immunologic, and genitourinary malformations.In this review, we discuss how these findings can be demonstrated using fetal MRI.

View Article: PubMed Central - HTML - PubMed

Affiliation: Cardiology Dept., Children's Hospital of Wisconsin.

ABSTRACT
Magnetic resonance imaging (MRI) is increasingly used as an investigation during fetal life, particularly for assessment of intracranial masses, congenital diaphragmatic hernia, myelomeningocele, and abdominal masses. As the number of scans increases, so is the variety of congenital malformations being recognized. It is axiomatic that interpretation of the findings is enhanced when attention is paid to the likely findings in the setting of known syndromes, this information then dictating the need for additional acquisition of images. One such syndrome is so-called "visceral heterotaxy", in which there is typically an isomeric, rather than a lateralized, arrangement of the thoracic and abdominal organs. Typically associated with complex congenital cardiac malformations, heterotaxy can also involve the central nervous system, and produce pulmonary, gastrointestinal, immunologic, and genitourinary malformations. In this review, we discuss how these findings can be demonstrated using fetal MRI.

No MeSH data available.


Related in: MedlinePlus