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A Systematic Review of Recent Advances in Equine Influenza Vaccination.

Paillot R - Vaccines (Basel) (2014)

Bottom Line: Equine influenza (EI) is a major respiratory disease of horses, which is still causing substantial outbreaks worldwide despite several decades of surveillance and prevention.The panel of EI vaccines commercially available is probably one of the most varied, including whole inactivated virus vaccines, Immuno-Stimulating Complex adjuvanted vaccines (ISCOM and ISCOM-Matrix), a live attenuated equine influenza virus (EIV) vaccine and a recombinant poxvirus-vectored vaccine.This systematic review reports the advances of EI vaccines during the last few years as well as some of the mechanisms behind the inefficient or sub-optimal response of horses to vaccination.

View Article: PubMed Central - PubMed

Affiliation: Animal Health Trust, Centre for Preventive Medicine, Lanwades Park, Newmarket, Suffolk CB8 7UU, UK. romain.paillot@aht.org.uk.

ABSTRACT
Equine influenza (EI) is a major respiratory disease of horses, which is still causing substantial outbreaks worldwide despite several decades of surveillance and prevention. Alongside quarantine procedures, vaccination is widely used to prevent or limit spread of the disease. The panel of EI vaccines commercially available is probably one of the most varied, including whole inactivated virus vaccines, Immuno-Stimulating Complex adjuvanted vaccines (ISCOM and ISCOM-Matrix), a live attenuated equine influenza virus (EIV) vaccine and a recombinant poxvirus-vectored vaccine. Several other strategies of vaccination are also evaluated. This systematic review reports the advances of EI vaccines during the last few years as well as some of the mechanisms behind the inefficient or sub-optimal response of horses to vaccination.

No MeSH data available.


Related in: MedlinePlus

Different types of EI vaccines.
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vaccines-02-00797-f004: Different types of EI vaccines.

Mentions: Vaccination is one of the most effective tools, alongside isolation, movement restriction and basic biosecurity measures [53,54], to prevent EIV infection or to limit its consequences. Equine influenza vaccines have been available since the 1960s and vaccination is mandatory in the UK for racing Thoroughbreds since 1981. Today, EI vaccines commercialised worldwide could be differentiated into three groups based on their technology (i.e., whole inactivated/sub-unit ISCOM-Matrix or ISCOM, live-attenuated and viral-vector based; Table 1, Figure 4). Several EI vaccines are licensed and sold in Europe [19]. These vaccine technologies have been previously described [55].


A Systematic Review of Recent Advances in Equine Influenza Vaccination.

Paillot R - Vaccines (Basel) (2014)

Different types of EI vaccines.
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4494246&req=5

vaccines-02-00797-f004: Different types of EI vaccines.
Mentions: Vaccination is one of the most effective tools, alongside isolation, movement restriction and basic biosecurity measures [53,54], to prevent EIV infection or to limit its consequences. Equine influenza vaccines have been available since the 1960s and vaccination is mandatory in the UK for racing Thoroughbreds since 1981. Today, EI vaccines commercialised worldwide could be differentiated into three groups based on their technology (i.e., whole inactivated/sub-unit ISCOM-Matrix or ISCOM, live-attenuated and viral-vector based; Table 1, Figure 4). Several EI vaccines are licensed and sold in Europe [19]. These vaccine technologies have been previously described [55].

Bottom Line: Equine influenza (EI) is a major respiratory disease of horses, which is still causing substantial outbreaks worldwide despite several decades of surveillance and prevention.The panel of EI vaccines commercially available is probably one of the most varied, including whole inactivated virus vaccines, Immuno-Stimulating Complex adjuvanted vaccines (ISCOM and ISCOM-Matrix), a live attenuated equine influenza virus (EIV) vaccine and a recombinant poxvirus-vectored vaccine.This systematic review reports the advances of EI vaccines during the last few years as well as some of the mechanisms behind the inefficient or sub-optimal response of horses to vaccination.

View Article: PubMed Central - PubMed

Affiliation: Animal Health Trust, Centre for Preventive Medicine, Lanwades Park, Newmarket, Suffolk CB8 7UU, UK. romain.paillot@aht.org.uk.

ABSTRACT
Equine influenza (EI) is a major respiratory disease of horses, which is still causing substantial outbreaks worldwide despite several decades of surveillance and prevention. Alongside quarantine procedures, vaccination is widely used to prevent or limit spread of the disease. The panel of EI vaccines commercially available is probably one of the most varied, including whole inactivated virus vaccines, Immuno-Stimulating Complex adjuvanted vaccines (ISCOM and ISCOM-Matrix), a live attenuated equine influenza virus (EIV) vaccine and a recombinant poxvirus-vectored vaccine. Several other strategies of vaccination are also evaluated. This systematic review reports the advances of EI vaccines during the last few years as well as some of the mechanisms behind the inefficient or sub-optimal response of horses to vaccination.

No MeSH data available.


Related in: MedlinePlus