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The Potential Impact of Preventive HIV Vaccines in China: Results and Benefits of a Multi-Province Modeling Collaboration.

Harmon T, Guo W, Stover J, Wu Z, Kaufman J, Schneider K, Liu L, Feng L, Schwartländer B - Vaccines (Basel) (2015)

Bottom Line: China's commitment to implementing established and emerging HIV/AIDS prevention and control strategies has led to substantial gains in terms of access to antiretroviral treatment and prevention services, but the evolving and multifaceted HIV/AIDS epidemic in China highlights the challenges of maintaining that response.This study presents modeling results exploring the potential impact of HIV vaccines in the Chinese context at varying efficacy and coverage rates, while further exploring the potential implications of vaccination programs aimed at reaching populations at highest risk of HIV infection.A preventive HIV vaccine would add a powerful tool to China's response, even if not 100% efficacious or available to the full population.

View Article: PubMed Central - PubMed

Affiliation: International AIDS Vaccine Initiative, 125 Broad St., 9th Floor, New York, NY 10004, USA. tharmon@iavi.org.

ABSTRACT
China's commitment to implementing established and emerging HIV/AIDS prevention and control strategies has led to substantial gains in terms of access to antiretroviral treatment and prevention services, but the evolving and multifaceted HIV/AIDS epidemic in China highlights the challenges of maintaining that response. This study presents modeling results exploring the potential impact of HIV vaccines in the Chinese context at varying efficacy and coverage rates, while further exploring the potential implications of vaccination programs aimed at reaching populations at highest risk of HIV infection. A preventive HIV vaccine would add a powerful tool to China's response, even if not 100% efficacious or available to the full population.

No MeSH data available.


Related in: MedlinePlus

New adult HIV infections in Sichuan province by risk groups in 2030.
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vaccines-03-00001-f004: New adult HIV infections in Sichuan province by risk groups in 2030.

Mentions: Exact information on the number of current new infections in different population groups in Sichuan is unavailable, but the modeling suggests that transmission in MSM communities and among individuals with a single partner who has other partners represent the largest drivers of incidence. Transmission due to injecting drug users and commercial sex is still important but less so than in the past. Preventive HIV vaccines would benefit all risk groups by reducing the probability of infection (Figure 4).


The Potential Impact of Preventive HIV Vaccines in China: Results and Benefits of a Multi-Province Modeling Collaboration.

Harmon T, Guo W, Stover J, Wu Z, Kaufman J, Schneider K, Liu L, Feng L, Schwartländer B - Vaccines (Basel) (2015)

New adult HIV infections in Sichuan province by risk groups in 2030.
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4494240&req=5

vaccines-03-00001-f004: New adult HIV infections in Sichuan province by risk groups in 2030.
Mentions: Exact information on the number of current new infections in different population groups in Sichuan is unavailable, but the modeling suggests that transmission in MSM communities and among individuals with a single partner who has other partners represent the largest drivers of incidence. Transmission due to injecting drug users and commercial sex is still important but less so than in the past. Preventive HIV vaccines would benefit all risk groups by reducing the probability of infection (Figure 4).

Bottom Line: China's commitment to implementing established and emerging HIV/AIDS prevention and control strategies has led to substantial gains in terms of access to antiretroviral treatment and prevention services, but the evolving and multifaceted HIV/AIDS epidemic in China highlights the challenges of maintaining that response.This study presents modeling results exploring the potential impact of HIV vaccines in the Chinese context at varying efficacy and coverage rates, while further exploring the potential implications of vaccination programs aimed at reaching populations at highest risk of HIV infection.A preventive HIV vaccine would add a powerful tool to China's response, even if not 100% efficacious or available to the full population.

View Article: PubMed Central - PubMed

Affiliation: International AIDS Vaccine Initiative, 125 Broad St., 9th Floor, New York, NY 10004, USA. tharmon@iavi.org.

ABSTRACT
China's commitment to implementing established and emerging HIV/AIDS prevention and control strategies has led to substantial gains in terms of access to antiretroviral treatment and prevention services, but the evolving and multifaceted HIV/AIDS epidemic in China highlights the challenges of maintaining that response. This study presents modeling results exploring the potential impact of HIV vaccines in the Chinese context at varying efficacy and coverage rates, while further exploring the potential implications of vaccination programs aimed at reaching populations at highest risk of HIV infection. A preventive HIV vaccine would add a powerful tool to China's response, even if not 100% efficacious or available to the full population.

No MeSH data available.


Related in: MedlinePlus