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Gallbladder perforation: a single center experience of 32 cases.

Gunasekaran G, Naik D, Gupta A, Bhandari V, Kuppusamy M, Kumar G, Chishi NS - Korean J Hepatobiliary Pancreat Surg (2015)

Bottom Line: The mean age of patients was 55.9 years.The histopathologic analysis in 28 patients who were operated on showed acute cholecystitis in 19 cases, acute-on-chronic cholecystitis in 4 cases, chronic cholecystitis in 4 cases, and mucinous adenocarcinoma of the gallbladder in a single case.Appropriate classification and management are essential.

View Article: PubMed Central - PubMed

Affiliation: Department of Surgery, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.

ABSTRACT

Backgrounds/aims: Gallbladder perforation is a rare but potentially fatal disease. We herein present our clinical experience in diagnosis and management of 32 cases of gallbladder perforation.

Methods: This retrospective study was conducted with inclusion of all cases of gallbladder perforation that presented to our hospital from January 2012 to November 2014. Cases of traumatic gallbladder perforation and patients younger than 12 years of age were excluded from this study.

Results: This study included 32 patients (13 males and 19 females). The mean age of patients was 55.9 years. Gallbladder perforation was most common in the 5th and 6th decade of life. The mean age of patients with type I, II, and III gallbladder perforation was 57.0 years, 57.6 years, and 49.8 years, respectively. The most common site of perforation was the fundus, followed by the body and Hartmann's pouch (24 : 5 : 2). Most of the type I gallbladder perforations were diagnosed intraoperatively, type II gallbladder perforations were diagnosed by enhanced abdominal computed tomography, and type III gallbladder perforations were diagnosed during laparoscopic cholecystectomy converted to open cholecystectomy for cholelithiasis. Mortality was highest in patients with type I gallbladder perforation. The mean hospital stay was 10.1 days, 6.4 days, and 9.2 days in patients with type I, II, and III gallbladder perforation, respectively. The histopathologic analysis in 28 patients who were operated on showed acute cholecystitis in 19 cases, acute-on-chronic cholecystitis in 4 cases, chronic cholecystitis in 4 cases, and mucinous adenocarcinoma of the gallbladder in a single case.

Conclusions: Gallbladder perforation represents a special diagnostic and surgical challenge. Appropriate classification and management are essential.

No MeSH data available.


Related in: MedlinePlus

Intraoperative photograph showing dense adhesions around the gallbladder in a patient with gallstone ileus (type III gallbladder perforation).
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Figure 1: Intraoperative photograph showing dense adhesions around the gallbladder in a patient with gallstone ileus (type III gallbladder perforation).

Mentions: The most common site of perforation was the fundus, followed by the body and Hartmann's pouch (24 : 5 : 2). The site of perforation could not be identified in a single case with type III gallbladder perforation due to dense adhesions, and this case was of gallstone ileus (Fig. 1). A proximal enterolithotomy (Fig. 2) was performed and a 2-stage procedure was planned for the patient.


Gallbladder perforation: a single center experience of 32 cases.

Gunasekaran G, Naik D, Gupta A, Bhandari V, Kuppusamy M, Kumar G, Chishi NS - Korean J Hepatobiliary Pancreat Surg (2015)

Intraoperative photograph showing dense adhesions around the gallbladder in a patient with gallstone ileus (type III gallbladder perforation).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4494096&req=5

Figure 1: Intraoperative photograph showing dense adhesions around the gallbladder in a patient with gallstone ileus (type III gallbladder perforation).
Mentions: The most common site of perforation was the fundus, followed by the body and Hartmann's pouch (24 : 5 : 2). The site of perforation could not be identified in a single case with type III gallbladder perforation due to dense adhesions, and this case was of gallstone ileus (Fig. 1). A proximal enterolithotomy (Fig. 2) was performed and a 2-stage procedure was planned for the patient.

Bottom Line: The mean age of patients was 55.9 years.The histopathologic analysis in 28 patients who were operated on showed acute cholecystitis in 19 cases, acute-on-chronic cholecystitis in 4 cases, chronic cholecystitis in 4 cases, and mucinous adenocarcinoma of the gallbladder in a single case.Appropriate classification and management are essential.

View Article: PubMed Central - PubMed

Affiliation: Department of Surgery, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.

ABSTRACT

Backgrounds/aims: Gallbladder perforation is a rare but potentially fatal disease. We herein present our clinical experience in diagnosis and management of 32 cases of gallbladder perforation.

Methods: This retrospective study was conducted with inclusion of all cases of gallbladder perforation that presented to our hospital from January 2012 to November 2014. Cases of traumatic gallbladder perforation and patients younger than 12 years of age were excluded from this study.

Results: This study included 32 patients (13 males and 19 females). The mean age of patients was 55.9 years. Gallbladder perforation was most common in the 5th and 6th decade of life. The mean age of patients with type I, II, and III gallbladder perforation was 57.0 years, 57.6 years, and 49.8 years, respectively. The most common site of perforation was the fundus, followed by the body and Hartmann's pouch (24 : 5 : 2). Most of the type I gallbladder perforations were diagnosed intraoperatively, type II gallbladder perforations were diagnosed by enhanced abdominal computed tomography, and type III gallbladder perforations were diagnosed during laparoscopic cholecystectomy converted to open cholecystectomy for cholelithiasis. Mortality was highest in patients with type I gallbladder perforation. The mean hospital stay was 10.1 days, 6.4 days, and 9.2 days in patients with type I, II, and III gallbladder perforation, respectively. The histopathologic analysis in 28 patients who were operated on showed acute cholecystitis in 19 cases, acute-on-chronic cholecystitis in 4 cases, chronic cholecystitis in 4 cases, and mucinous adenocarcinoma of the gallbladder in a single case.

Conclusions: Gallbladder perforation represents a special diagnostic and surgical challenge. Appropriate classification and management are essential.

No MeSH data available.


Related in: MedlinePlus