A New Class of SINEs with snRNA Gene-Derived Heads.
Bottom Line: SINEU-2 is the only SINE family that was active after the split of crocodiles and gharials.All SINEU families, especially SINEU-3, are preferentially inserted into a family of Mariner DNA transposon, Mariner-N4_AMi.A group of Tx1 non-long terminal repeat retrotransposons designated Tx1-Mar also show target preference for Mariner-N4_AMi, indicating that SINEU was mobilized by Tx1-Mar.
Affiliation: Genetic Information Research Institute, Los Altos, CA email@example.com.Show MeSH
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Mentions: Some families of Tx1 non-LTR retrotransposons from crocodilians are also preferentially inserted into Mariner-N4_AMi. On the basis of the phylogeny of RT sequences, crocodilian Tx1 families are classified into three groups (fig. 3, asterisks). One group is coclustered with Keno. Most crocodilian Tx1 families in this group are preferentially inserted into Mariner-N4_AMi and its related transposons (supplementary figs. S3 and S4, Supplementary Material online). This Tx1 group was designated “Tx1-Mar.” Exceptions are Tx1-8_Crp and Tx1-4_AMi, preferentially inserted into specific groups of LTR retrotransposons.Fig. 3.—
Affiliation: Genetic Information Research Institute, Los Altos, CA firstname.lastname@example.org.