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Construction and evaluation of controlled-release delivery system of Abamectin using porous silica nanoparticles as carriers.

Wang Y, Cui H, Sun C, Zhao X, Cui B - Nanoscale Res Lett (2014)

Bottom Line: Photolysis and poor solubility in water of Abamectin are key issues to be addressed, which causes low bioavailability and residual pollution.In this study, a novel hydrophilic delivery system through loading Abamectin with porous silica nanoparticles (Abam-PSNs) was developed in order to improve the chemical stability, dispersity, and the controlled release of Abamectin.These results suggest that Abam-PSNs can significantly improve the performance of controllable release, photostability, and water solubility of Abamectin by changing the porous structure of silica nanoparticles, which is favorable to improve the bioavailability and reduce the residues of pesticides.

View Article: PubMed Central - PubMed

Affiliation: Institute of Environment and Sustainable Development in Agriculture, Chinese Academy of Agricultural Sciences, Beijing, 100081, China, ywangbless@gmail.com.

ABSTRACT
Photolysis and poor solubility in water of Abamectin are key issues to be addressed, which causes low bioavailability and residual pollution. In this study, a novel hydrophilic delivery system through loading Abamectin with porous silica nanoparticles (Abam-PSNs) was developed in order to improve the chemical stability, dispersity, and the controlled release of Abamectin. These results suggest that Abam-PSNs can significantly improve the performance of controllable release, photostability, and water solubility of Abamectin by changing the porous structure of silica nanoparticles, which is favorable to improve the bioavailability and reduce the residues of pesticides.

No MeSH data available.


Release profile of Abamectin loaded by Abam-PSNs with different porous structure. The pure Abamectin was used as the control in the experiments. Abam-PSNs-1, Abam-PSNs-2, Abam-PSNs-3, and Abam-PSNs-4 samples were etched for 45, 75, 105, and 120 min, respectively.
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Fig7: Release profile of Abamectin loaded by Abam-PSNs with different porous structure. The pure Abamectin was used as the control in the experiments. Abam-PSNs-1, Abam-PSNs-2, Abam-PSNs-3, and Abam-PSNs-4 samples were etched for 45, 75, 105, and 120 min, respectively.

Mentions: The release profiles of Abamectin from Abam-PSNs with different porous structures are shown in FigureĀ 7. Compared with pure Abamectin, initial burst release of Abam-PSNs is not so obvious. As expected, Abam-PSNs exhibit slower release rates due to the porous structure on the surface which is favorable to prolong validity period and reduce leaching loss of Abamectin.Figure 7


Construction and evaluation of controlled-release delivery system of Abamectin using porous silica nanoparticles as carriers.

Wang Y, Cui H, Sun C, Zhao X, Cui B - Nanoscale Res Lett (2014)

Release profile of Abamectin loaded by Abam-PSNs with different porous structure. The pure Abamectin was used as the control in the experiments. Abam-PSNs-1, Abam-PSNs-2, Abam-PSNs-3, and Abam-PSNs-4 samples were etched for 45, 75, 105, and 120 min, respectively.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4494038&req=5

Fig7: Release profile of Abamectin loaded by Abam-PSNs with different porous structure. The pure Abamectin was used as the control in the experiments. Abam-PSNs-1, Abam-PSNs-2, Abam-PSNs-3, and Abam-PSNs-4 samples were etched for 45, 75, 105, and 120 min, respectively.
Mentions: The release profiles of Abamectin from Abam-PSNs with different porous structures are shown in FigureĀ 7. Compared with pure Abamectin, initial burst release of Abam-PSNs is not so obvious. As expected, Abam-PSNs exhibit slower release rates due to the porous structure on the surface which is favorable to prolong validity period and reduce leaching loss of Abamectin.Figure 7

Bottom Line: Photolysis and poor solubility in water of Abamectin are key issues to be addressed, which causes low bioavailability and residual pollution.In this study, a novel hydrophilic delivery system through loading Abamectin with porous silica nanoparticles (Abam-PSNs) was developed in order to improve the chemical stability, dispersity, and the controlled release of Abamectin.These results suggest that Abam-PSNs can significantly improve the performance of controllable release, photostability, and water solubility of Abamectin by changing the porous structure of silica nanoparticles, which is favorable to improve the bioavailability and reduce the residues of pesticides.

View Article: PubMed Central - PubMed

Affiliation: Institute of Environment and Sustainable Development in Agriculture, Chinese Academy of Agricultural Sciences, Beijing, 100081, China, ywangbless@gmail.com.

ABSTRACT
Photolysis and poor solubility in water of Abamectin are key issues to be addressed, which causes low bioavailability and residual pollution. In this study, a novel hydrophilic delivery system through loading Abamectin with porous silica nanoparticles (Abam-PSNs) was developed in order to improve the chemical stability, dispersity, and the controlled release of Abamectin. These results suggest that Abam-PSNs can significantly improve the performance of controllable release, photostability, and water solubility of Abamectin by changing the porous structure of silica nanoparticles, which is favorable to improve the bioavailability and reduce the residues of pesticides.

No MeSH data available.