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Construction and evaluation of controlled-release delivery system of Abamectin using porous silica nanoparticles as carriers.

Wang Y, Cui H, Sun C, Zhao X, Cui B - Nanoscale Res Lett (2014)

Bottom Line: Photolysis and poor solubility in water of Abamectin are key issues to be addressed, which causes low bioavailability and residual pollution.In this study, a novel hydrophilic delivery system through loading Abamectin with porous silica nanoparticles (Abam-PSNs) was developed in order to improve the chemical stability, dispersity, and the controlled release of Abamectin.These results suggest that Abam-PSNs can significantly improve the performance of controllable release, photostability, and water solubility of Abamectin by changing the porous structure of silica nanoparticles, which is favorable to improve the bioavailability and reduce the residues of pesticides.

View Article: PubMed Central - PubMed

Affiliation: Institute of Environment and Sustainable Development in Agriculture, Chinese Academy of Agricultural Sciences, Beijing, 100081, China, ywangbless@gmail.com.

ABSTRACT
Photolysis and poor solubility in water of Abamectin are key issues to be addressed, which causes low bioavailability and residual pollution. In this study, a novel hydrophilic delivery system through loading Abamectin with porous silica nanoparticles (Abam-PSNs) was developed in order to improve the chemical stability, dispersity, and the controlled release of Abamectin. These results suggest that Abam-PSNs can significantly improve the performance of controllable release, photostability, and water solubility of Abamectin by changing the porous structure of silica nanoparticles, which is favorable to improve the bioavailability and reduce the residues of pesticides.

No MeSH data available.


TEM images of the PSNs etched for different times. (a) 45 min, (b) 75 min, (c) 105 min, and (d)120 min.
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Fig4: TEM images of the PSNs etched for different times. (a) 45 min, (b) 75 min, (c) 105 min, and (d)120 min.

Mentions: FigureĀ 4 showed TEM images of four kinds of PSNs with different porous structure etched for 45, 75, 105, and 120 min. The imaging results indicated that all of the PSNs have good monodispersity under four different etching conditions, and the porous structure was gradually developed with increased etching time without obvious change of particle size. With the increase of etching time from 45 to 120 min, OH- ions of NaOH can gradually diffuse into the interior of silica nanoparticles and eventually producing porous structures upon continued etching. Continued reaction further makes the appearance of porous structure more pronounced, and the PSNs come to appear rougher and less homogeneous in transmission contrast due to the etching effect. The results suggested that the porous structure of PSNs can be effectively controlled by changing the etching time.Figure 4


Construction and evaluation of controlled-release delivery system of Abamectin using porous silica nanoparticles as carriers.

Wang Y, Cui H, Sun C, Zhao X, Cui B - Nanoscale Res Lett (2014)

TEM images of the PSNs etched for different times. (a) 45 min, (b) 75 min, (c) 105 min, and (d)120 min.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4494038&req=5

Fig4: TEM images of the PSNs etched for different times. (a) 45 min, (b) 75 min, (c) 105 min, and (d)120 min.
Mentions: FigureĀ 4 showed TEM images of four kinds of PSNs with different porous structure etched for 45, 75, 105, and 120 min. The imaging results indicated that all of the PSNs have good monodispersity under four different etching conditions, and the porous structure was gradually developed with increased etching time without obvious change of particle size. With the increase of etching time from 45 to 120 min, OH- ions of NaOH can gradually diffuse into the interior of silica nanoparticles and eventually producing porous structures upon continued etching. Continued reaction further makes the appearance of porous structure more pronounced, and the PSNs come to appear rougher and less homogeneous in transmission contrast due to the etching effect. The results suggested that the porous structure of PSNs can be effectively controlled by changing the etching time.Figure 4

Bottom Line: Photolysis and poor solubility in water of Abamectin are key issues to be addressed, which causes low bioavailability and residual pollution.In this study, a novel hydrophilic delivery system through loading Abamectin with porous silica nanoparticles (Abam-PSNs) was developed in order to improve the chemical stability, dispersity, and the controlled release of Abamectin.These results suggest that Abam-PSNs can significantly improve the performance of controllable release, photostability, and water solubility of Abamectin by changing the porous structure of silica nanoparticles, which is favorable to improve the bioavailability and reduce the residues of pesticides.

View Article: PubMed Central - PubMed

Affiliation: Institute of Environment and Sustainable Development in Agriculture, Chinese Academy of Agricultural Sciences, Beijing, 100081, China, ywangbless@gmail.com.

ABSTRACT
Photolysis and poor solubility in water of Abamectin are key issues to be addressed, which causes low bioavailability and residual pollution. In this study, a novel hydrophilic delivery system through loading Abamectin with porous silica nanoparticles (Abam-PSNs) was developed in order to improve the chemical stability, dispersity, and the controlled release of Abamectin. These results suggest that Abam-PSNs can significantly improve the performance of controllable release, photostability, and water solubility of Abamectin by changing the porous structure of silica nanoparticles, which is favorable to improve the bioavailability and reduce the residues of pesticides.

No MeSH data available.