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Construction and evaluation of controlled-release delivery system of Abamectin using porous silica nanoparticles as carriers.

Wang Y, Cui H, Sun C, Zhao X, Cui B - Nanoscale Res Lett (2014)

Bottom Line: Photolysis and poor solubility in water of Abamectin are key issues to be addressed, which causes low bioavailability and residual pollution.In this study, a novel hydrophilic delivery system through loading Abamectin with porous silica nanoparticles (Abam-PSNs) was developed in order to improve the chemical stability, dispersity, and the controlled release of Abamectin.These results suggest that Abam-PSNs can significantly improve the performance of controllable release, photostability, and water solubility of Abamectin by changing the porous structure of silica nanoparticles, which is favorable to improve the bioavailability and reduce the residues of pesticides.

View Article: PubMed Central - PubMed

Affiliation: Institute of Environment and Sustainable Development in Agriculture, Chinese Academy of Agricultural Sciences, Beijing, 100081, China, ywangbless@gmail.com.

ABSTRACT
Photolysis and poor solubility in water of Abamectin are key issues to be addressed, which causes low bioavailability and residual pollution. In this study, a novel hydrophilic delivery system through loading Abamectin with porous silica nanoparticles (Abam-PSNs) was developed in order to improve the chemical stability, dispersity, and the controlled release of Abamectin. These results suggest that Abam-PSNs can significantly improve the performance of controllable release, photostability, and water solubility of Abamectin by changing the porous structure of silica nanoparticles, which is favorable to improve the bioavailability and reduce the residues of pesticides.

No MeSH data available.


The nitrogen adsorption-desorption curves and BJH pore size distributions of silica nanoparticles before and after etching.
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Fig3: The nitrogen adsorption-desorption curves and BJH pore size distributions of silica nanoparticles before and after etching.

Mentions: Experimental procedures for the construction of Abam-PSNs delivery system were shown in Figure 1. The SEM images of the representative PSNs are shown in Figure 2. The PSNs show uniform spherical shapes with the average diameter of 320 nm. The uniformity and dispersity of the PSNs are favorable to improve the dispersion, adhesion, and permeability of pesticide on target crops as pesticide carriers. SEM imaging confirmed that the surfaces of the PSNs were of obvious porous structures after NaOH etching treatment. The BET results indicated that the specific surface area of the PSNs increased from 11.31 m2/g up to 318.62 m2/g after etching. The increase of specific surface area can be attributed to gradual etching of the interior and surface layer of silica nanoparticles, which is beneficial to increase the loading capacity of the PSNs as pesticide carriers. The nitrogen adsorption-desorption curves and BJH pore size distributions of silica nanoparticles before and after etching are shown in Figure 3, respectively. The nitrogen adsorption-desorption isotherm of PSNs has different opening and closing pressures before and after etching, indicating the change of pore size in the process of etching. The pore volume of the PSNs remarkably increased after etching, and the pore size distribution of the PSNs was narrow and most of the pores had a diameter of 12 nm.Figure 1


Construction and evaluation of controlled-release delivery system of Abamectin using porous silica nanoparticles as carriers.

Wang Y, Cui H, Sun C, Zhao X, Cui B - Nanoscale Res Lett (2014)

The nitrogen adsorption-desorption curves and BJH pore size distributions of silica nanoparticles before and after etching.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4494038&req=5

Fig3: The nitrogen adsorption-desorption curves and BJH pore size distributions of silica nanoparticles before and after etching.
Mentions: Experimental procedures for the construction of Abam-PSNs delivery system were shown in Figure 1. The SEM images of the representative PSNs are shown in Figure 2. The PSNs show uniform spherical shapes with the average diameter of 320 nm. The uniformity and dispersity of the PSNs are favorable to improve the dispersion, adhesion, and permeability of pesticide on target crops as pesticide carriers. SEM imaging confirmed that the surfaces of the PSNs were of obvious porous structures after NaOH etching treatment. The BET results indicated that the specific surface area of the PSNs increased from 11.31 m2/g up to 318.62 m2/g after etching. The increase of specific surface area can be attributed to gradual etching of the interior and surface layer of silica nanoparticles, which is beneficial to increase the loading capacity of the PSNs as pesticide carriers. The nitrogen adsorption-desorption curves and BJH pore size distributions of silica nanoparticles before and after etching are shown in Figure 3, respectively. The nitrogen adsorption-desorption isotherm of PSNs has different opening and closing pressures before and after etching, indicating the change of pore size in the process of etching. The pore volume of the PSNs remarkably increased after etching, and the pore size distribution of the PSNs was narrow and most of the pores had a diameter of 12 nm.Figure 1

Bottom Line: Photolysis and poor solubility in water of Abamectin are key issues to be addressed, which causes low bioavailability and residual pollution.In this study, a novel hydrophilic delivery system through loading Abamectin with porous silica nanoparticles (Abam-PSNs) was developed in order to improve the chemical stability, dispersity, and the controlled release of Abamectin.These results suggest that Abam-PSNs can significantly improve the performance of controllable release, photostability, and water solubility of Abamectin by changing the porous structure of silica nanoparticles, which is favorable to improve the bioavailability and reduce the residues of pesticides.

View Article: PubMed Central - PubMed

Affiliation: Institute of Environment and Sustainable Development in Agriculture, Chinese Academy of Agricultural Sciences, Beijing, 100081, China, ywangbless@gmail.com.

ABSTRACT
Photolysis and poor solubility in water of Abamectin are key issues to be addressed, which causes low bioavailability and residual pollution. In this study, a novel hydrophilic delivery system through loading Abamectin with porous silica nanoparticles (Abam-PSNs) was developed in order to improve the chemical stability, dispersity, and the controlled release of Abamectin. These results suggest that Abam-PSNs can significantly improve the performance of controllable release, photostability, and water solubility of Abamectin by changing the porous structure of silica nanoparticles, which is favorable to improve the bioavailability and reduce the residues of pesticides.

No MeSH data available.