Limits...
Soft UV nanoimprint lithography-designed highly sensitive substrates for SERS detection.

Cottat M, Lidgi-Guigui N, Tijunelyte I, Barbillon G, Hamouda F, Gogol P, Aassime A, Lourtioz JM, Bartenlian B, de la Chapelle ML - Nanoscale Res Lett (2014)

Bottom Line: Gold nanocylinders (GNCs) showed to be very sensitive and specific sensing surfaces.Indeed, we demonstrated that less than 4 ×10(6) avidin molecules were detected and contributed to the surface-enhanced Raman scattering (SERS) signal.Thus, the soft UV-NIL technique allows to obtain quickly very sensitive substrates for SERS biosensing on surfaces of 1 mm (2).

View Article: PubMed Central - PubMed

Affiliation: CSPBAT (UMR 7244), CNRS-Université Paris 13, 74 rue Marcel Cachin, 93017, Bobigny, France, maximilien.cottat@univ-paris13.fr.

ABSTRACT
We report on the use of soft UV nanoimprint lithography (UV-NIL) for the development of reproducible, millimeter-sized, and sensitive substrates for SERS detection. The used geometry for plasmonic nanostructures is the cylinder. Gold nanocylinders (GNCs) showed to be very sensitive and specific sensing surfaces. Indeed, we demonstrated that less than 4 ×10(6) avidin molecules were detected and contributed to the surface-enhanced Raman scattering (SERS) signal. Thus, the soft UV-NIL technique allows to obtain quickly very sensitive substrates for SERS biosensing on surfaces of 1 mm (2).

No MeSH data available.


Gold nanocylinder fabrication by UV-NIL.(a) Imprint in AMONIL resist (scale bar = 200 nm), (b) SEM image of the obtained nanocylinders (scale bar = 1 μm), and the inset represents a zoom of a single nanodisk (scale bar = 50 nm).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC4494019&req=5

Fig3: Gold nanocylinder fabrication by UV-NIL.(a) Imprint in AMONIL resist (scale bar = 200 nm), (b) SEM image of the obtained nanocylinders (scale bar = 1 μm), and the inset represents a zoom of a single nanodisk (scale bar = 50 nm).

Mentions: Firstly, the imprint process is realized in the AMONIL, which is deposited on a PMMA resist. The polymerization is performed with UV exposure (λ=365 nm) with 10 mW/cm 2 power during time exposure of 20 min. The imprint pressure is 200 mbar. Figure 3a shows a cross section SEM view with nanoholes in the AMONIL resist. The average diameter of holes is around 220 nm, and the residual thickness of AMONIL is around 20 nm. Thus, the AMONIL presence in the hole ground needs a specific RIE process. The removal of the residual AMONIL and the PMMA etch conditions have been reported in reference [17]. During this PMMA etching, we have a good selectivity between the PMMA and AMONIL (vPMMA/vAMONIL=2.7). After this etch, a gold thin layer (50 nm) is deposited by electron beam evaporation in order to realize the plasmonic nanocylinders. Previously, an adhesion layer (Cr) for gold is evaporated (3 nm). Figure 3b shows SEM image of gold nanocylinder arrays on 1 mm 2. The obtained dimensions are approximately 220 nm for the diameter, 50 nm for the height, and a periodicity of 400 nm. The inset of the Figure 3b is a zoom of a single nanodisk, and we observed a surface roughness relatively important with small tips on the nanodisk border.Figure 3


Soft UV nanoimprint lithography-designed highly sensitive substrates for SERS detection.

Cottat M, Lidgi-Guigui N, Tijunelyte I, Barbillon G, Hamouda F, Gogol P, Aassime A, Lourtioz JM, Bartenlian B, de la Chapelle ML - Nanoscale Res Lett (2014)

Gold nanocylinder fabrication by UV-NIL.(a) Imprint in AMONIL resist (scale bar = 200 nm), (b) SEM image of the obtained nanocylinders (scale bar = 1 μm), and the inset represents a zoom of a single nanodisk (scale bar = 50 nm).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4494019&req=5

Fig3: Gold nanocylinder fabrication by UV-NIL.(a) Imprint in AMONIL resist (scale bar = 200 nm), (b) SEM image of the obtained nanocylinders (scale bar = 1 μm), and the inset represents a zoom of a single nanodisk (scale bar = 50 nm).
Mentions: Firstly, the imprint process is realized in the AMONIL, which is deposited on a PMMA resist. The polymerization is performed with UV exposure (λ=365 nm) with 10 mW/cm 2 power during time exposure of 20 min. The imprint pressure is 200 mbar. Figure 3a shows a cross section SEM view with nanoholes in the AMONIL resist. The average diameter of holes is around 220 nm, and the residual thickness of AMONIL is around 20 nm. Thus, the AMONIL presence in the hole ground needs a specific RIE process. The removal of the residual AMONIL and the PMMA etch conditions have been reported in reference [17]. During this PMMA etching, we have a good selectivity between the PMMA and AMONIL (vPMMA/vAMONIL=2.7). After this etch, a gold thin layer (50 nm) is deposited by electron beam evaporation in order to realize the plasmonic nanocylinders. Previously, an adhesion layer (Cr) for gold is evaporated (3 nm). Figure 3b shows SEM image of gold nanocylinder arrays on 1 mm 2. The obtained dimensions are approximately 220 nm for the diameter, 50 nm for the height, and a periodicity of 400 nm. The inset of the Figure 3b is a zoom of a single nanodisk, and we observed a surface roughness relatively important with small tips on the nanodisk border.Figure 3

Bottom Line: Gold nanocylinders (GNCs) showed to be very sensitive and specific sensing surfaces.Indeed, we demonstrated that less than 4 ×10(6) avidin molecules were detected and contributed to the surface-enhanced Raman scattering (SERS) signal.Thus, the soft UV-NIL technique allows to obtain quickly very sensitive substrates for SERS biosensing on surfaces of 1 mm (2).

View Article: PubMed Central - PubMed

Affiliation: CSPBAT (UMR 7244), CNRS-Université Paris 13, 74 rue Marcel Cachin, 93017, Bobigny, France, maximilien.cottat@univ-paris13.fr.

ABSTRACT
We report on the use of soft UV nanoimprint lithography (UV-NIL) for the development of reproducible, millimeter-sized, and sensitive substrates for SERS detection. The used geometry for plasmonic nanostructures is the cylinder. Gold nanocylinders (GNCs) showed to be very sensitive and specific sensing surfaces. Indeed, we demonstrated that less than 4 ×10(6) avidin molecules were detected and contributed to the surface-enhanced Raman scattering (SERS) signal. Thus, the soft UV-NIL technique allows to obtain quickly very sensitive substrates for SERS biosensing on surfaces of 1 mm (2).

No MeSH data available.