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Infratentorial ependymomas--a study of the centre in Katowice.

Mandera M, Makarska J, Sobol G, Musioł K - Childs Nerv Syst (2015)

Bottom Line: The study was conducted on a group of 19 patients, 13 boys and 6 girls aged 3 months to 16 years, with infratentorial ependymoma treated at the Department of Paediatric Neurosurgery of the Medical University of Silesia in Katowice from January 2000 until December 2008.There has been no statistically significant influence of the histopathological type of ependymoma on the result of treatment.The tendency to report better results of treatment of non-anaplastic ependymoma seems to derive from a statistically higher frequency of total removal of tumours of this type.

View Article: PubMed Central - PubMed

Affiliation: Department of Emergency Medicine and Paediatric Neurosurgery, Medical University of Silesia, ul. Medyków 16, Katowice, Poland.

ABSTRACT
The aim of the study was to assess the correlation of the results of the treatment of infratentorial ependymomas with the degree of resection and histopathological diagnosis. The study was conducted on a group of 19 patients, 13 boys and 6 girls aged 3 months to 16 years, with infratentorial ependymoma treated at the Department of Paediatric Neurosurgery of the Medical University of Silesia in Katowice from January 2000 until December 2008. The most significant factor having an impact on overall survival and progression-free survival was totality of tumour resection. There has been no statistically significant influence of the histopathological type of ependymoma on the result of treatment. The tendency to report better results of treatment of non-anaplastic ependymoma seems to derive from a statistically higher frequency of total removal of tumours of this type.

No MeSH data available.


Related in: MedlinePlus

Progression-free survival (PFS) in the group of patients involved in the study
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Related In: Results  -  Collection


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Fig1: Progression-free survival (PFS) in the group of patients involved in the study

Mentions: The time of observation varied from 3 to 113 months (40.2 months in average). Tumour progression or tumour recurrence was noted in eight (42.1 %) patients within the period of 3 to 60 months. The average time until progression or recurrence amounted to 25.8 months. There were eight (42.1 %) patients who died after an average time of 37 months (from 6 to 90 months), one of them (12.5 %) with diagnosed ependymoma and seven of them (87.5 %) with diagnosed anaplastic ependymoma. All deaths were pronounced in a group of patients with subtotal resection. Progression-free survival (PFS) and overall survival (OS) were assessed in the group of patients, which are illustrated in Figs. 1 and 2.Fig. 1


Infratentorial ependymomas--a study of the centre in Katowice.

Mandera M, Makarska J, Sobol G, Musioł K - Childs Nerv Syst (2015)

Progression-free survival (PFS) in the group of patients involved in the study
© Copyright Policy - OpenAccess
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4493855&req=5

Fig1: Progression-free survival (PFS) in the group of patients involved in the study
Mentions: The time of observation varied from 3 to 113 months (40.2 months in average). Tumour progression or tumour recurrence was noted in eight (42.1 %) patients within the period of 3 to 60 months. The average time until progression or recurrence amounted to 25.8 months. There were eight (42.1 %) patients who died after an average time of 37 months (from 6 to 90 months), one of them (12.5 %) with diagnosed ependymoma and seven of them (87.5 %) with diagnosed anaplastic ependymoma. All deaths were pronounced in a group of patients with subtotal resection. Progression-free survival (PFS) and overall survival (OS) were assessed in the group of patients, which are illustrated in Figs. 1 and 2.Fig. 1

Bottom Line: The study was conducted on a group of 19 patients, 13 boys and 6 girls aged 3 months to 16 years, with infratentorial ependymoma treated at the Department of Paediatric Neurosurgery of the Medical University of Silesia in Katowice from January 2000 until December 2008.There has been no statistically significant influence of the histopathological type of ependymoma on the result of treatment.The tendency to report better results of treatment of non-anaplastic ependymoma seems to derive from a statistically higher frequency of total removal of tumours of this type.

View Article: PubMed Central - PubMed

Affiliation: Department of Emergency Medicine and Paediatric Neurosurgery, Medical University of Silesia, ul. Medyków 16, Katowice, Poland.

ABSTRACT
The aim of the study was to assess the correlation of the results of the treatment of infratentorial ependymomas with the degree of resection and histopathological diagnosis. The study was conducted on a group of 19 patients, 13 boys and 6 girls aged 3 months to 16 years, with infratentorial ependymoma treated at the Department of Paediatric Neurosurgery of the Medical University of Silesia in Katowice from January 2000 until December 2008. The most significant factor having an impact on overall survival and progression-free survival was totality of tumour resection. There has been no statistically significant influence of the histopathological type of ependymoma on the result of treatment. The tendency to report better results of treatment of non-anaplastic ependymoma seems to derive from a statistically higher frequency of total removal of tumours of this type.

No MeSH data available.


Related in: MedlinePlus