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Ultrasound measurement of optic nerve diameter and optic nerve sheath diameter in healthy Chinese adults.

Chen H, Ding GS, Zhao YC, Yu RG, Zhou JX - BMC Neurol (2015)

Bottom Line: There was no significant difference in ETD, OND or ONSD between male and female, or between left and right eye.ONSD was significantly correlated with OND (r = 0.62, P < 0.001), and the median OND/ONSD ratio (interquartile range) was 0.63 (0.59 to 0.67).The median OND/ONSD ratio is 0.63 and this parameter warrants further investigation in patients with brain injury.

View Article: PubMed Central - PubMed

Affiliation: Department of Critical Care Medicine, Beijing Tiantan Hospital, Capital Medical University, No 6, TiantanXili, Dongcheng District, Beijing, 100050, China. baojr2@163.com.

ABSTRACT

Background: Measurement of optic nerve sheath diameter (ONSD) is a fast and non-invasive method in detecting elevated intracranial pressure. However, the reported normal range of ONSD was inconsistent. The objective of the study was to determine the normal range of ONSD in healthy Chinese adults.

Methods: Eyeball transverse diameter (ETD), optic nerve diameter (OND), and ONSD were measured by ultrasound examination in healthy adult volunteers. The OND and ONSD were assessed 3 mm behind the globe. The section showing maximal transverse diameter of the eyeball was frozen and the diameter was measured. Each ETD, OND and ONSD was examined twice and the mean value was calculated.

Results: A total of 519 healthy volunteers were included in the study. The median (interquartile range) of ETD, OND and ONSD were 22.3 (21.6 to 23.1) mm, 3.2 (2.9 to 3.4) mm, and 5.1 (4.7 to 5.4) mm, respectively. The 95% percentile of ONSD was 5.9 mm. There was no significant difference in ETD, OND or ONSD between male and female, or between left and right eye. ONSD was significantly correlated with OND (r = 0.62, P < 0.001), and the median OND/ONSD ratio (interquartile range) was 0.63 (0.59 to 0.67).

Conclusions: The median and the 95% percentile of sonographic measurement of ONSD are 5.1 mm and 5.9 mm in healthy Chinese adults. The ONSD is correlated with OND, while independent of gender, age, height, weight and ETD. The median OND/ONSD ratio is 0.63 and this parameter warrants further investigation in patients with brain injury.

No MeSH data available.


Related in: MedlinePlus

Transbulbar sonography of the optic nerve and the optic nerve sheath. OND and ONSD were measured 3 mm behind the globe using an electronic caliper along the axis. The interval between “+” marks was OND, and the interval between “x” marks was ONSD
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Fig1: Transbulbar sonography of the optic nerve and the optic nerve sheath. OND and ONSD were measured 3 mm behind the globe using an electronic caliper along the axis. The interval between “+” marks was OND, and the interval between “x” marks was ONSD

Mentions: At study entry, the gender, age, height and weight of the subject were collected. The ultrasound examination was conducted in B-mode by using a Philips Envisor C (M2540A) ultrasound system and a 12–3 MHz linear array probe (Philips Medical Systems, Bothell WA, USA), by one of the two sonographers (GS.D. and YC.Z.). Volunteers were examined in supine position with their head elevated to the angle of 20-30°. A thick layer of gel was applied over the closed upper eyelid. The probe was placed on the gel in the temporal area of the eyelid to prevent pressing the eye. The ETD, OND and ONSD were measured. OND and ONSD were assessed 3 mm behind the globe using an electronic caliper along the axis perpendicularly the retina (Fig. 1). In order to gauge the ETD, horizontal sections of eyeball were obtained by scanning from the superior to the inferior side. The section showing the maximal ETD was frozen and the diameter was measured using the electronic caliper. Each ETD, OND and ONSD was examined twice and the mean value was calculated. We also calculated the OND/ONSD ratio.Fig. 1


Ultrasound measurement of optic nerve diameter and optic nerve sheath diameter in healthy Chinese adults.

Chen H, Ding GS, Zhao YC, Yu RG, Zhou JX - BMC Neurol (2015)

Transbulbar sonography of the optic nerve and the optic nerve sheath. OND and ONSD were measured 3 mm behind the globe using an electronic caliper along the axis. The interval between “+” marks was OND, and the interval between “x” marks was ONSD
© Copyright Policy - open-access
Related In: Results  -  Collection

License 1 - License 2
Show All Figures
getmorefigures.php?uid=PMC4493801&req=5

Fig1: Transbulbar sonography of the optic nerve and the optic nerve sheath. OND and ONSD were measured 3 mm behind the globe using an electronic caliper along the axis. The interval between “+” marks was OND, and the interval between “x” marks was ONSD
Mentions: At study entry, the gender, age, height and weight of the subject were collected. The ultrasound examination was conducted in B-mode by using a Philips Envisor C (M2540A) ultrasound system and a 12–3 MHz linear array probe (Philips Medical Systems, Bothell WA, USA), by one of the two sonographers (GS.D. and YC.Z.). Volunteers were examined in supine position with their head elevated to the angle of 20-30°. A thick layer of gel was applied over the closed upper eyelid. The probe was placed on the gel in the temporal area of the eyelid to prevent pressing the eye. The ETD, OND and ONSD were measured. OND and ONSD were assessed 3 mm behind the globe using an electronic caliper along the axis perpendicularly the retina (Fig. 1). In order to gauge the ETD, horizontal sections of eyeball were obtained by scanning from the superior to the inferior side. The section showing the maximal ETD was frozen and the diameter was measured using the electronic caliper. Each ETD, OND and ONSD was examined twice and the mean value was calculated. We also calculated the OND/ONSD ratio.Fig. 1

Bottom Line: There was no significant difference in ETD, OND or ONSD between male and female, or between left and right eye.ONSD was significantly correlated with OND (r = 0.62, P < 0.001), and the median OND/ONSD ratio (interquartile range) was 0.63 (0.59 to 0.67).The median OND/ONSD ratio is 0.63 and this parameter warrants further investigation in patients with brain injury.

View Article: PubMed Central - PubMed

Affiliation: Department of Critical Care Medicine, Beijing Tiantan Hospital, Capital Medical University, No 6, TiantanXili, Dongcheng District, Beijing, 100050, China. baojr2@163.com.

ABSTRACT

Background: Measurement of optic nerve sheath diameter (ONSD) is a fast and non-invasive method in detecting elevated intracranial pressure. However, the reported normal range of ONSD was inconsistent. The objective of the study was to determine the normal range of ONSD in healthy Chinese adults.

Methods: Eyeball transverse diameter (ETD), optic nerve diameter (OND), and ONSD were measured by ultrasound examination in healthy adult volunteers. The OND and ONSD were assessed 3 mm behind the globe. The section showing maximal transverse diameter of the eyeball was frozen and the diameter was measured. Each ETD, OND and ONSD was examined twice and the mean value was calculated.

Results: A total of 519 healthy volunteers were included in the study. The median (interquartile range) of ETD, OND and ONSD were 22.3 (21.6 to 23.1) mm, 3.2 (2.9 to 3.4) mm, and 5.1 (4.7 to 5.4) mm, respectively. The 95% percentile of ONSD was 5.9 mm. There was no significant difference in ETD, OND or ONSD between male and female, or between left and right eye. ONSD was significantly correlated with OND (r = 0.62, P < 0.001), and the median OND/ONSD ratio (interquartile range) was 0.63 (0.59 to 0.67).

Conclusions: The median and the 95% percentile of sonographic measurement of ONSD are 5.1 mm and 5.9 mm in healthy Chinese adults. The ONSD is correlated with OND, while independent of gender, age, height, weight and ETD. The median OND/ONSD ratio is 0.63 and this parameter warrants further investigation in patients with brain injury.

No MeSH data available.


Related in: MedlinePlus