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Fabrication and Characterization of Nanoporous Niobia, and Nanotubular Tantala, Titania and Zirconia via Anodization.

Minagar S, Berndt CC, Wen C - J Funct Biomater (2015)

Bottom Line: Therefore, four kinds of metal oxide nanoporous and nanotubular Ta2O5, Nb2O5, ZrO2 and TiO2 were fabricated via anodization.It was found that the nanoporous Ta2O5 exhibited an irregular porous structure, high roughness and high surface energy as compared to bare tantalum metal; and exhibited the most superior bioactivity after annealing among the four kinds of nanoporous structures.The nanoporous Nb2O5 showed a uniform porous structure and low roughness, but no bioactivity before annealing.

View Article: PubMed Central - PubMed

Affiliation: Faculty of Science, Engineering and Technology, Swinburne University of Technology, Hawthorn, Victoria 3122, Australia. sminagar@swin.edu.au.

ABSTRACT
Valve metals such as titanium (Ti), zirconium (Zr), niobium (Nb) and tantalum (Ta) that confer a stable oxide layer on their surfaces are commonly used as implant materials or alloying elements for titanium-based implants, due to their exceptional high corrosion resistance and excellent biocompatibility. The aim of this study was to investigate the bioactivity of the nanostructures of tantala (Ta2O5), niobia (Nb2O5), zirconia (ZrO2) and titania (TiO2) in accordance to their roughness and wettability. Therefore, four kinds of metal oxide nanoporous and nanotubular Ta2O5, Nb2O5, ZrO2 and TiO2 were fabricated via anodization. The nanosize distribution, morphology and the physical and chemical properties of the nanolayers and their surface energies and bioactivities were investigated using SEM-EDS, X-ray diffraction (XRD) analysis and 3D profilometer. It was found that the nanoporous Ta2O5 exhibited an irregular porous structure, high roughness and high surface energy as compared to bare tantalum metal; and exhibited the most superior bioactivity after annealing among the four kinds of nanoporous structures. The nanoporous Nb2O5 showed a uniform porous structure and low roughness, but no bioactivity before annealing. Overall, the nanoporous and nanotubular layers of Ta2O5, Nb2O5, ZrO2 and TiO2 demonstrated promising potential for enhanced bioactivity to improve their biomedical application alone or to improve the usage in other biocompatible metal implants.

No MeSH data available.


Bioactivity of biocompatible nanoporous and nanotubular oxide metals after 3 weeks in m-SBF at 37 °C.
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jfb-06-00153-f008: Bioactivity of biocompatible nanoporous and nanotubular oxide metals after 3 weeks in m-SBF at 37 °C.

Mentions: Artificial implant materials upon implantation in vivo are encapsulated by fibrous tissues that isolate them from the surrounding bone. This is not the ideal healing mechanism, whereas a bioactive material is preferred which bonds to living bone by forming a carbonated apatite layer on their surfaces similar to hydroxyapatite (HA) of bone composition [48]. The bioactivity of the biocompatible metals with the as-formed and annealed conditions of the nanoporous and nanotubular metal oxides was assessed by immersion in the m-SBF for a period up to three weeks. The response of the oxide layers to the m-SBF immersion was observed after one day and three weeks. After one-day immersion, no growth of HA was detectable on the surfaces of the as-formed and annealed nanoporous Ta2O5 and Nb2O5 and the nanotubular TiO2 and ZrO2. However, after three weeks immersion as shown in Figure 7, HA were deposited onto the surfaces of the nanoporous and nanotubular layers. The atomic ratio of calcium to phosphate calculated using EDS results after three weeks is indicated in Figure 8.


Fabrication and Characterization of Nanoporous Niobia, and Nanotubular Tantala, Titania and Zirconia via Anodization.

Minagar S, Berndt CC, Wen C - J Funct Biomater (2015)

Bioactivity of biocompatible nanoporous and nanotubular oxide metals after 3 weeks in m-SBF at 37 °C.
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4493505&req=5

jfb-06-00153-f008: Bioactivity of biocompatible nanoporous and nanotubular oxide metals after 3 weeks in m-SBF at 37 °C.
Mentions: Artificial implant materials upon implantation in vivo are encapsulated by fibrous tissues that isolate them from the surrounding bone. This is not the ideal healing mechanism, whereas a bioactive material is preferred which bonds to living bone by forming a carbonated apatite layer on their surfaces similar to hydroxyapatite (HA) of bone composition [48]. The bioactivity of the biocompatible metals with the as-formed and annealed conditions of the nanoporous and nanotubular metal oxides was assessed by immersion in the m-SBF for a period up to three weeks. The response of the oxide layers to the m-SBF immersion was observed after one day and three weeks. After one-day immersion, no growth of HA was detectable on the surfaces of the as-formed and annealed nanoporous Ta2O5 and Nb2O5 and the nanotubular TiO2 and ZrO2. However, after three weeks immersion as shown in Figure 7, HA were deposited onto the surfaces of the nanoporous and nanotubular layers. The atomic ratio of calcium to phosphate calculated using EDS results after three weeks is indicated in Figure 8.

Bottom Line: Therefore, four kinds of metal oxide nanoporous and nanotubular Ta2O5, Nb2O5, ZrO2 and TiO2 were fabricated via anodization.It was found that the nanoporous Ta2O5 exhibited an irregular porous structure, high roughness and high surface energy as compared to bare tantalum metal; and exhibited the most superior bioactivity after annealing among the four kinds of nanoporous structures.The nanoporous Nb2O5 showed a uniform porous structure and low roughness, but no bioactivity before annealing.

View Article: PubMed Central - PubMed

Affiliation: Faculty of Science, Engineering and Technology, Swinburne University of Technology, Hawthorn, Victoria 3122, Australia. sminagar@swin.edu.au.

ABSTRACT
Valve metals such as titanium (Ti), zirconium (Zr), niobium (Nb) and tantalum (Ta) that confer a stable oxide layer on their surfaces are commonly used as implant materials or alloying elements for titanium-based implants, due to their exceptional high corrosion resistance and excellent biocompatibility. The aim of this study was to investigate the bioactivity of the nanostructures of tantala (Ta2O5), niobia (Nb2O5), zirconia (ZrO2) and titania (TiO2) in accordance to their roughness and wettability. Therefore, four kinds of metal oxide nanoporous and nanotubular Ta2O5, Nb2O5, ZrO2 and TiO2 were fabricated via anodization. The nanosize distribution, morphology and the physical and chemical properties of the nanolayers and their surface energies and bioactivities were investigated using SEM-EDS, X-ray diffraction (XRD) analysis and 3D profilometer. It was found that the nanoporous Ta2O5 exhibited an irregular porous structure, high roughness and high surface energy as compared to bare tantalum metal; and exhibited the most superior bioactivity after annealing among the four kinds of nanoporous structures. The nanoporous Nb2O5 showed a uniform porous structure and low roughness, but no bioactivity before annealing. Overall, the nanoporous and nanotubular layers of Ta2O5, Nb2O5, ZrO2 and TiO2 demonstrated promising potential for enhanced bioactivity to improve their biomedical application alone or to improve the usage in other biocompatible metal implants.

No MeSH data available.