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Primary Dural Spinal Lymphoma Presentation of a Rare Spinal Tumor Case.

Çeçen DA, Tatarlı N, Turan Süslü H, Özdoğan S, Barışık NÖ - Case Rep Surg (2015)

Bottom Line: He experienced a good outcome after four years.Conclusion.In cases of progressive paraparesis, there should be immediate surgical intervention in the case of denovo disease, followed by combined radiotherapy and chemotherapy procedures.

View Article: PubMed Central - PubMed

Affiliation: Department of Neurosurgery, Dr. Lütfi Kırdar Kartal Education and Research Hospital, 34852 Istanbul, Turkey.

ABSTRACT
Background. Primary spinal dural lymphomas (PSDL) are tumors with characteristic histopathology of a lymphoma, which are completely in the spinal epidural space without any other systemic involvement. Extranodal primary lymphoma involving nervous system prefers thalamus/basal ganglia, periventricular region, cerebellum, eyes, meninges/dura, and cranial nerves or spinal cord. Rare spinal localization with acute spinal cord compression is worth attention. Case Presentation. A 48-year-old male presented with a several-month-long history of upper back pain. Lately, he had numbness and weakness at both lower extremities and was unable to walk for one week. A spinal MRI showed a thoracic lesion with cord compression at T2-T4 levels. The patient underwent surgical decompression, with his final histopathology showing diffuse large B-cell lymphoma. Systemic work-up was negative for nodal disease. Following surgery, he received radiotherapy combined with chemotherapy. He experienced a good outcome after four years. Conclusion. The upper thoracic cord is a rare location for primary spinal lesions/metastases, both of which prefer the lower thoracic and upper lumbar regions. In cases of progressive paraparesis, there should be immediate surgical intervention in the case of denovo disease, followed by combined radiotherapy and chemotherapy procedures.

No MeSH data available.


Related in: MedlinePlus

(a) Axial T2-weighted MRI shows thoracic epidural lesion with cord compression at the T2–T4 levels, extending to the paraspinal muscles. (b) Sagittal T2-weighted MRI shows dural mass. (c) Images showing T2-weighted sagittal and axial MR scans.
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fig1: (a) Axial T2-weighted MRI shows thoracic epidural lesion with cord compression at the T2–T4 levels, extending to the paraspinal muscles. (b) Sagittal T2-weighted MRI shows dural mass. (c) Images showing T2-weighted sagittal and axial MR scans.

Mentions: A spinal MRI showed a thoracic epidural lesion with cord compression at the T2–T4 levels, extending to the paraspinal muscles (Figures 1(a), 1(b), and 1(c)).


Primary Dural Spinal Lymphoma Presentation of a Rare Spinal Tumor Case.

Çeçen DA, Tatarlı N, Turan Süslü H, Özdoğan S, Barışık NÖ - Case Rep Surg (2015)

(a) Axial T2-weighted MRI shows thoracic epidural lesion with cord compression at the T2–T4 levels, extending to the paraspinal muscles. (b) Sagittal T2-weighted MRI shows dural mass. (c) Images showing T2-weighted sagittal and axial MR scans.
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4493298&req=5

fig1: (a) Axial T2-weighted MRI shows thoracic epidural lesion with cord compression at the T2–T4 levels, extending to the paraspinal muscles. (b) Sagittal T2-weighted MRI shows dural mass. (c) Images showing T2-weighted sagittal and axial MR scans.
Mentions: A spinal MRI showed a thoracic epidural lesion with cord compression at the T2–T4 levels, extending to the paraspinal muscles (Figures 1(a), 1(b), and 1(c)).

Bottom Line: He experienced a good outcome after four years.Conclusion.In cases of progressive paraparesis, there should be immediate surgical intervention in the case of denovo disease, followed by combined radiotherapy and chemotherapy procedures.

View Article: PubMed Central - PubMed

Affiliation: Department of Neurosurgery, Dr. Lütfi Kırdar Kartal Education and Research Hospital, 34852 Istanbul, Turkey.

ABSTRACT
Background. Primary spinal dural lymphomas (PSDL) are tumors with characteristic histopathology of a lymphoma, which are completely in the spinal epidural space without any other systemic involvement. Extranodal primary lymphoma involving nervous system prefers thalamus/basal ganglia, periventricular region, cerebellum, eyes, meninges/dura, and cranial nerves or spinal cord. Rare spinal localization with acute spinal cord compression is worth attention. Case Presentation. A 48-year-old male presented with a several-month-long history of upper back pain. Lately, he had numbness and weakness at both lower extremities and was unable to walk for one week. A spinal MRI showed a thoracic lesion with cord compression at T2-T4 levels. The patient underwent surgical decompression, with his final histopathology showing diffuse large B-cell lymphoma. Systemic work-up was negative for nodal disease. Following surgery, he received radiotherapy combined with chemotherapy. He experienced a good outcome after four years. Conclusion. The upper thoracic cord is a rare location for primary spinal lesions/metastases, both of which prefer the lower thoracic and upper lumbar regions. In cases of progressive paraparesis, there should be immediate surgical intervention in the case of denovo disease, followed by combined radiotherapy and chemotherapy procedures.

No MeSH data available.


Related in: MedlinePlus