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Pulmonic Valve Repair in a Patient with Isolated Pulmonic Valve Endocarditis and Sickle Cell Disease.

Glew T, Feliciano M, Finkielstein D, Hecht S, Hoffman D - Case Rep Cardiol (2015)

Bottom Line: A 49-year-old woman with sickle cell disease presented with one month of exertional dyspnea, weakness, and fever and was diagnosed with isolated pulmonic valve endocarditis secondary to methicillin-resistant Staphylococcus bacteremia in the setting of a peripherally inserted central venous catheter.In conclusion, isolated pulmonic valve endocarditis is a rare cause of infective endocarditis that warrants a high index of clinical suspicion.Furthermore the management of patients with sickle cell disease and endocarditis requires special consideration.

View Article: PubMed Central - PubMed

Affiliation: Department of Cardiology, Mount Sinai Beth Israel, New York, NY 10003, USA.

ABSTRACT
A 49-year-old woman with sickle cell disease presented with one month of exertional dyspnea, weakness, and fever and was diagnosed with isolated pulmonic valve endocarditis secondary to methicillin-resistant Staphylococcus bacteremia in the setting of a peripherally inserted central venous catheter. Chest computerized tomography showed multiple bilateral pulmonary nodular opacities consistent with septic emboli. Transthoracic and transesophageal echocardiograms revealed a large echodensity on the pulmonic valve requiring vegetation excision and pulmonic valve repair. In conclusion, isolated pulmonic valve endocarditis is a rare cause of infective endocarditis that warrants a high index of clinical suspicion. Furthermore the management of patients with sickle cell disease and endocarditis requires special consideration.

No MeSH data available.


Related in: MedlinePlus

The pulmonic valve in vivo (a) and the excised valve leaflet (b).
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fig3: The pulmonic valve in vivo (a) and the excised valve leaflet (b).

Mentions: Twenty-five days after her initial presentation she underwent pulmonic valve repair. While on cardiopulmonary bypass normothermia was maintained and 2.5 × 2 cm pulmonic valve vegetation was excised en bloc with the left cusp of the pulmonic valve (Figures 3(a) and 3(b)). The resected leaflet was replaced with glutaraldehyde treated bovine pericardial patch shaped to match one of the other pulmonic cusps and sewn into place along the annulus with a continuous polypropylene suture. The excised pulmonic valve vegetation was sent to pathology and revealed bacterial colonies in fibrinous exudates, consistent with bacterial endocarditis.


Pulmonic Valve Repair in a Patient with Isolated Pulmonic Valve Endocarditis and Sickle Cell Disease.

Glew T, Feliciano M, Finkielstein D, Hecht S, Hoffman D - Case Rep Cardiol (2015)

The pulmonic valve in vivo (a) and the excised valve leaflet (b).
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4493266&req=5

fig3: The pulmonic valve in vivo (a) and the excised valve leaflet (b).
Mentions: Twenty-five days after her initial presentation she underwent pulmonic valve repair. While on cardiopulmonary bypass normothermia was maintained and 2.5 × 2 cm pulmonic valve vegetation was excised en bloc with the left cusp of the pulmonic valve (Figures 3(a) and 3(b)). The resected leaflet was replaced with glutaraldehyde treated bovine pericardial patch shaped to match one of the other pulmonic cusps and sewn into place along the annulus with a continuous polypropylene suture. The excised pulmonic valve vegetation was sent to pathology and revealed bacterial colonies in fibrinous exudates, consistent with bacterial endocarditis.

Bottom Line: A 49-year-old woman with sickle cell disease presented with one month of exertional dyspnea, weakness, and fever and was diagnosed with isolated pulmonic valve endocarditis secondary to methicillin-resistant Staphylococcus bacteremia in the setting of a peripherally inserted central venous catheter.In conclusion, isolated pulmonic valve endocarditis is a rare cause of infective endocarditis that warrants a high index of clinical suspicion.Furthermore the management of patients with sickle cell disease and endocarditis requires special consideration.

View Article: PubMed Central - PubMed

Affiliation: Department of Cardiology, Mount Sinai Beth Israel, New York, NY 10003, USA.

ABSTRACT
A 49-year-old woman with sickle cell disease presented with one month of exertional dyspnea, weakness, and fever and was diagnosed with isolated pulmonic valve endocarditis secondary to methicillin-resistant Staphylococcus bacteremia in the setting of a peripherally inserted central venous catheter. Chest computerized tomography showed multiple bilateral pulmonary nodular opacities consistent with septic emboli. Transthoracic and transesophageal echocardiograms revealed a large echodensity on the pulmonic valve requiring vegetation excision and pulmonic valve repair. In conclusion, isolated pulmonic valve endocarditis is a rare cause of infective endocarditis that warrants a high index of clinical suspicion. Furthermore the management of patients with sickle cell disease and endocarditis requires special consideration.

No MeSH data available.


Related in: MedlinePlus