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Differences in Clinical and Laboratory Findings between Group D and Non-Group D Non-Typhoidal Salmonella Gastroenteritis in Children.

Park HK, Rhie K, Yeom JS, Park JS, Park ES, Seo JH, Lim JY, Park CH, Woo HO, Youn HS, Kang KR, Park JJ - Pediatr Gastroenterol Hepatol Nutr (2015)

Bottom Line: A positive Widal test result was observed in 53.3% of group D and 6.7% of non-group D NTS cases (O-titer, p=0.030; H-titer, p=0.039).The more severe clinical features such as headache, fever, and higher Widal titers were found to be indicative of group D NTS gastroenteritis.Additionally, group D NTS gastroenteritis was more commonly found in older patients.

View Article: PubMed Central - PubMed

Affiliation: Department of Pediatrics, Gyeongsang Institute of Health Science, Gyeongsang National University School of Medicine, Jinju, Korea.

ABSTRACT

Purpose: To investigate the differences in clinical features and laboratory findings between group D and non-group D non-typhoidal Salmonella (NTS) gastroenteritis in children.

Methods: A retrospective chart review of children diagnosed with NTS confirmed by culture study was performed. The clinical features and laboratory findings of group D and non-group D NTS were compared.

Results: From 2003 to 2012, 75 cases were diagnosed as NTS at our center. The number of group D and non-group D patients was 45 and 30, respectively. The mean age was higher in group D than in non-group D patients (5.1 years vs. 3.4 years, p=0.038). Headaches were more frequently observed (p=0.046) and hematochezia was less frequently observed (p=0.017) in group D than in non-group D NTS gastroenteritis patients. A positive Widal test result was observed in 53.3% of group D and 6.7% of non-group D NTS cases (O-titer, p=0.030; H-titer, p=0.039). There were no differences in white blood cell counts, level of C-reactive protein and rate of antimicrobial resistance between group D and non-group D cases.

Conclusion: The more severe clinical features such as headache, fever, and higher Widal titers were found to be indicative of group D NTS gastroenteritis. Additionally, group D NTS gastroenteritis was more commonly found in older patients. Therefore, old age, fever, headache, and a positive Widal test are more indicative of group D NTS than non-group D NTS gastroenteritis. Pathophysiological mechanisms may differ across serologic groups.

No MeSH data available.


Related in: MedlinePlus

Monthly Incidence rate of non-typhoidal salmonellosis. The incidence rate was highest in May and was higher from July to October compared with other months (p=0.007).
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Figure 2: Monthly Incidence rate of non-typhoidal salmonellosis. The incidence rate was highest in May and was higher from July to October compared with other months (p=0.007).

Mentions: The incidence rate of NTS gastroenteritis increased from 2003 to 2012 (p=0.033, Fig. 1). The lowest incidence rate was 1, in 2003, and the highest was 11, in 2011. The leading Salmonella serogroup was group D (60.0%), followed by group B (25.3%), group C (9.3%), and group E (5.3%). The monthly incidence rate of NTS gastroenteritis was higher from May to October than from November to April (p=0.007, Fig. 2).


Differences in Clinical and Laboratory Findings between Group D and Non-Group D Non-Typhoidal Salmonella Gastroenteritis in Children.

Park HK, Rhie K, Yeom JS, Park JS, Park ES, Seo JH, Lim JY, Park CH, Woo HO, Youn HS, Kang KR, Park JJ - Pediatr Gastroenterol Hepatol Nutr (2015)

Monthly Incidence rate of non-typhoidal salmonellosis. The incidence rate was highest in May and was higher from July to October compared with other months (p=0.007).
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4493251&req=5

Figure 2: Monthly Incidence rate of non-typhoidal salmonellosis. The incidence rate was highest in May and was higher from July to October compared with other months (p=0.007).
Mentions: The incidence rate of NTS gastroenteritis increased from 2003 to 2012 (p=0.033, Fig. 1). The lowest incidence rate was 1, in 2003, and the highest was 11, in 2011. The leading Salmonella serogroup was group D (60.0%), followed by group B (25.3%), group C (9.3%), and group E (5.3%). The monthly incidence rate of NTS gastroenteritis was higher from May to October than from November to April (p=0.007, Fig. 2).

Bottom Line: A positive Widal test result was observed in 53.3% of group D and 6.7% of non-group D NTS cases (O-titer, p=0.030; H-titer, p=0.039).The more severe clinical features such as headache, fever, and higher Widal titers were found to be indicative of group D NTS gastroenteritis.Additionally, group D NTS gastroenteritis was more commonly found in older patients.

View Article: PubMed Central - PubMed

Affiliation: Department of Pediatrics, Gyeongsang Institute of Health Science, Gyeongsang National University School of Medicine, Jinju, Korea.

ABSTRACT

Purpose: To investigate the differences in clinical features and laboratory findings between group D and non-group D non-typhoidal Salmonella (NTS) gastroenteritis in children.

Methods: A retrospective chart review of children diagnosed with NTS confirmed by culture study was performed. The clinical features and laboratory findings of group D and non-group D NTS were compared.

Results: From 2003 to 2012, 75 cases were diagnosed as NTS at our center. The number of group D and non-group D patients was 45 and 30, respectively. The mean age was higher in group D than in non-group D patients (5.1 years vs. 3.4 years, p=0.038). Headaches were more frequently observed (p=0.046) and hematochezia was less frequently observed (p=0.017) in group D than in non-group D NTS gastroenteritis patients. A positive Widal test result was observed in 53.3% of group D and 6.7% of non-group D NTS cases (O-titer, p=0.030; H-titer, p=0.039). There were no differences in white blood cell counts, level of C-reactive protein and rate of antimicrobial resistance between group D and non-group D cases.

Conclusion: The more severe clinical features such as headache, fever, and higher Widal titers were found to be indicative of group D NTS gastroenteritis. Additionally, group D NTS gastroenteritis was more commonly found in older patients. Therefore, old age, fever, headache, and a positive Widal test are more indicative of group D NTS than non-group D NTS gastroenteritis. Pathophysiological mechanisms may differ across serologic groups.

No MeSH data available.


Related in: MedlinePlus