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Atypical β-Catenin Activated Child Hepatocellular Tumor.

Turan A, Unlu HA, Karakus E, Yazal Erdem A, Yakut ZI - Pediatr Gastroenterol Hepatol Nutr (2015)

Bottom Line: Hepatocellular adenomas are a benign, focal, hepatic neoplasm that have been divided into four subtypes according to the genetic and pathological features.The current study aimed to report the magnetic resonance imaging features of a well differentiated hepatocellular carcinoma that developed on the basis of β-catenin activated hepatocellular adenomas in a child.In this case, atypical diffuse steatosis was determined in the lesion.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiology, Diskapi Yildirim Beyazit Training and Research Hospital, Ankara, Turkey.

ABSTRACT
Hepatocellular adenomas are a benign, focal, hepatic neoplasm that have been divided into four subtypes according to the genetic and pathological features. The β-catenin activated subtype accounts for 10-15% of all hepatocellular adenomas and specific magnetic resonance imaging features have been defined for different hepatocellular adenomas subtypes. The current study aimed to report the magnetic resonance imaging features of a well differentiated hepatocellular carcinoma that developed on the basis of β-catenin activated hepatocellular adenomas in a child. In this case, atypical diffuse steatosis was determined in the lesion. In the literature, diffuse steatosis, which is defined as a feature of the hepatocyte nuclear factor-1α-inactivated hepatocellular adenomas subtype, has not been previously reported in any β-catenin activated hepatocellular adenomas case. Interlacing magnetic resonance imaging findings between subtypes show that there are still many mysteries about this topic and larger studies are warranted.

No MeSH data available.


Related in: MedlinePlus

A large fatty mass (arrow) was observed in right liver lobe in contrasted axial computed tomography. The hounsfield unit of the central point circle was -37.
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Figure 1: A large fatty mass (arrow) was observed in right liver lobe in contrasted axial computed tomography. The hounsfield unit of the central point circle was -37.

Mentions: Abdominal ultrasound (USG) revealed a lobulated, heterogeneous, hyperechoic mass with a diameter of 14 cm in the right lobe of the liver. In computed tomography (CT), a heterogeneous, hypodense, fatty, lobulated huge mass was present, which enhanced heterogeneously. The density of tumor was measured -37 hounsfield unit in post-contrast image (Fig. 1).


Atypical β-Catenin Activated Child Hepatocellular Tumor.

Turan A, Unlu HA, Karakus E, Yazal Erdem A, Yakut ZI - Pediatr Gastroenterol Hepatol Nutr (2015)

A large fatty mass (arrow) was observed in right liver lobe in contrasted axial computed tomography. The hounsfield unit of the central point circle was -37.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4493249&req=5

Figure 1: A large fatty mass (arrow) was observed in right liver lobe in contrasted axial computed tomography. The hounsfield unit of the central point circle was -37.
Mentions: Abdominal ultrasound (USG) revealed a lobulated, heterogeneous, hyperechoic mass with a diameter of 14 cm in the right lobe of the liver. In computed tomography (CT), a heterogeneous, hypodense, fatty, lobulated huge mass was present, which enhanced heterogeneously. The density of tumor was measured -37 hounsfield unit in post-contrast image (Fig. 1).

Bottom Line: Hepatocellular adenomas are a benign, focal, hepatic neoplasm that have been divided into four subtypes according to the genetic and pathological features.The current study aimed to report the magnetic resonance imaging features of a well differentiated hepatocellular carcinoma that developed on the basis of β-catenin activated hepatocellular adenomas in a child.In this case, atypical diffuse steatosis was determined in the lesion.

View Article: PubMed Central - PubMed

Affiliation: Department of Radiology, Diskapi Yildirim Beyazit Training and Research Hospital, Ankara, Turkey.

ABSTRACT
Hepatocellular adenomas are a benign, focal, hepatic neoplasm that have been divided into four subtypes according to the genetic and pathological features. The β-catenin activated subtype accounts for 10-15% of all hepatocellular adenomas and specific magnetic resonance imaging features have been defined for different hepatocellular adenomas subtypes. The current study aimed to report the magnetic resonance imaging features of a well differentiated hepatocellular carcinoma that developed on the basis of β-catenin activated hepatocellular adenomas in a child. In this case, atypical diffuse steatosis was determined in the lesion. In the literature, diffuse steatosis, which is defined as a feature of the hepatocyte nuclear factor-1α-inactivated hepatocellular adenomas subtype, has not been previously reported in any β-catenin activated hepatocellular adenomas case. Interlacing magnetic resonance imaging findings between subtypes show that there are still many mysteries about this topic and larger studies are warranted.

No MeSH data available.


Related in: MedlinePlus