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Abdominal Subcutaneous Fat Thickness Measured by Ultrasonography Correlates with Hyperlipidemia and Steatohepatitis in Obese Children.

Lee SH, Kim D, Baek MY, Tchah H, Kim YS, Ryoo E, Kim YM - Pediatr Gastroenterol Hepatol Nutr (2015)

Bottom Line: According to the grade of hepatic steasosis, the average values of midline abdominal subcutaneous fat thickness and right flank abdominal subcutaneous fat thickness measured 2.9±0.8 cm and 1.9±0.7 cm in the normal group, 3.3±0.8 cm and 2.0±0.7 cm in grade I, 3.8±0.8 cm and 2.3±0.8 cm in grade II, and 4.1±0.8 cm and 2.8±1.4 cm in grade III, respectively.Abdominal subcutaneous fat thickness correlated with grade of hepatic steatosis (p<0.01).Abdominal subcutaneous fat thickness measured by US can be used as a reliable predictor of possible hyperlipidemia and steatohepatitis in children, especially during the adolescent stage.

View Article: PubMed Central - PubMed

Affiliation: Department of Pediatrics, Gachon University Gil Medical Center, Incheon, Korea.

ABSTRACT

Purpose: The aim of this study is to evaluate the relationship between abdominal subcutaneous fat thickness measured by ultrasonography (US) and serum lipid profile and liver transaminases in obese children.

Methods: One hundred and sixty-six children diagnosed with obesity from May 2001 to December 2013 were included in this study. Data on serum lipid profile and liver transaminases were collected from clinical records. Abdominal subcutaneous fat thickness and grade of hepatic steatosis were evaluated by US.

Results: Of the 166 children, 107 were diagnosed with hepatic steatosis by US, 46 with grade I, 56 with grade II, and five children with grade III. According to the grade of hepatic steasosis, the average values of midline abdominal subcutaneous fat thickness and right flank abdominal subcutaneous fat thickness measured 2.9±0.8 cm and 1.9±0.7 cm in the normal group, 3.3±0.8 cm and 2.0±0.7 cm in grade I, 3.8±0.8 cm and 2.3±0.8 cm in grade II, and 4.1±0.8 cm and 2.8±1.4 cm in grade III, respectively. Abdominal subcutaneous fat thickness correlated with grade of hepatic steatosis (p<0.01). In addition, abdominal subcutaneous fat thickness correlated with concentration of serum lipids and liver transaminases in the age group of 12-14 years (p<0.01).

Conclusion: Abdominal subcutaneous fat thickness measured by US can be used as a reliable predictor of possible hyperlipidemia and steatohepatitis in children, especially during the adolescent stage.

No MeSH data available.


Related in: MedlinePlus

Abdominal subcutaneous fat on ultrasonography image. (A) Midline abdominal subcutaneous fat thickness (about 3.9 cm) was measured transversely at the one centimeter caudal to the umbilicus level. (B) Right flank abdominal subcutaneous fat thickness (about 1.9 cm) was measured coronally at two locations of the right flank, and the average value was recorded. The image was captured when the transducer just had contact with the skin to avoid compressing the subcutaneous adipose fascia.
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Figure 1: Abdominal subcutaneous fat on ultrasonography image. (A) Midline abdominal subcutaneous fat thickness (about 3.9 cm) was measured transversely at the one centimeter caudal to the umbilicus level. (B) Right flank abdominal subcutaneous fat thickness (about 1.9 cm) was measured coronally at two locations of the right flank, and the average value was recorded. The image was captured when the transducer just had contact with the skin to avoid compressing the subcutaneous adipose fascia.

Mentions: Abdominal subcutaneous fat thickness was measured in the supine position during normal respiration with minimal pressure applied by the US probe. Midline abdominal subcutaneous fat thickness (MASFT) was measured transversely at one centimeter caudal to the umbilicus level and the right flank abdominal subcutaneous fat thickness (RFASFT) was measured coronally at two locations of the right flank, with the average value being recorded (Fig. 1). Measurements of MASFT and RFASFT of all 166 children were correlated with other parameters.


Abdominal Subcutaneous Fat Thickness Measured by Ultrasonography Correlates with Hyperlipidemia and Steatohepatitis in Obese Children.

Lee SH, Kim D, Baek MY, Tchah H, Kim YS, Ryoo E, Kim YM - Pediatr Gastroenterol Hepatol Nutr (2015)

Abdominal subcutaneous fat on ultrasonography image. (A) Midline abdominal subcutaneous fat thickness (about 3.9 cm) was measured transversely at the one centimeter caudal to the umbilicus level. (B) Right flank abdominal subcutaneous fat thickness (about 1.9 cm) was measured coronally at two locations of the right flank, and the average value was recorded. The image was captured when the transducer just had contact with the skin to avoid compressing the subcutaneous adipose fascia.
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4493243&req=5

Figure 1: Abdominal subcutaneous fat on ultrasonography image. (A) Midline abdominal subcutaneous fat thickness (about 3.9 cm) was measured transversely at the one centimeter caudal to the umbilicus level. (B) Right flank abdominal subcutaneous fat thickness (about 1.9 cm) was measured coronally at two locations of the right flank, and the average value was recorded. The image was captured when the transducer just had contact with the skin to avoid compressing the subcutaneous adipose fascia.
Mentions: Abdominal subcutaneous fat thickness was measured in the supine position during normal respiration with minimal pressure applied by the US probe. Midline abdominal subcutaneous fat thickness (MASFT) was measured transversely at one centimeter caudal to the umbilicus level and the right flank abdominal subcutaneous fat thickness (RFASFT) was measured coronally at two locations of the right flank, with the average value being recorded (Fig. 1). Measurements of MASFT and RFASFT of all 166 children were correlated with other parameters.

Bottom Line: According to the grade of hepatic steasosis, the average values of midline abdominal subcutaneous fat thickness and right flank abdominal subcutaneous fat thickness measured 2.9±0.8 cm and 1.9±0.7 cm in the normal group, 3.3±0.8 cm and 2.0±0.7 cm in grade I, 3.8±0.8 cm and 2.3±0.8 cm in grade II, and 4.1±0.8 cm and 2.8±1.4 cm in grade III, respectively.Abdominal subcutaneous fat thickness correlated with grade of hepatic steatosis (p<0.01).Abdominal subcutaneous fat thickness measured by US can be used as a reliable predictor of possible hyperlipidemia and steatohepatitis in children, especially during the adolescent stage.

View Article: PubMed Central - PubMed

Affiliation: Department of Pediatrics, Gachon University Gil Medical Center, Incheon, Korea.

ABSTRACT

Purpose: The aim of this study is to evaluate the relationship between abdominal subcutaneous fat thickness measured by ultrasonography (US) and serum lipid profile and liver transaminases in obese children.

Methods: One hundred and sixty-six children diagnosed with obesity from May 2001 to December 2013 were included in this study. Data on serum lipid profile and liver transaminases were collected from clinical records. Abdominal subcutaneous fat thickness and grade of hepatic steatosis were evaluated by US.

Results: Of the 166 children, 107 were diagnosed with hepatic steatosis by US, 46 with grade I, 56 with grade II, and five children with grade III. According to the grade of hepatic steasosis, the average values of midline abdominal subcutaneous fat thickness and right flank abdominal subcutaneous fat thickness measured 2.9±0.8 cm and 1.9±0.7 cm in the normal group, 3.3±0.8 cm and 2.0±0.7 cm in grade I, 3.8±0.8 cm and 2.3±0.8 cm in grade II, and 4.1±0.8 cm and 2.8±1.4 cm in grade III, respectively. Abdominal subcutaneous fat thickness correlated with grade of hepatic steatosis (p<0.01). In addition, abdominal subcutaneous fat thickness correlated with concentration of serum lipids and liver transaminases in the age group of 12-14 years (p<0.01).

Conclusion: Abdominal subcutaneous fat thickness measured by US can be used as a reliable predictor of possible hyperlipidemia and steatohepatitis in children, especially during the adolescent stage.

No MeSH data available.


Related in: MedlinePlus