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Zinc and copper levels are not correlated with angiographically-defined coronary artery disease in sudanese patients.

Lutfi MF, Elhakeem RF, Khogaly RS, Abdrabo AA, Ali AB, Gasim GI, Adam I - Front Physiol (2015)

Bottom Line: We performed a cross-sectional study.One hundred forty-two patients were enrolled.Sociodemographic and medical characteristics were collected using a questionnaire.

View Article: PubMed Central - PubMed

Affiliation: Faculty of Medicine, Alneelain University Khartoum, Sudan.

ABSTRACT
We investigated zinc and copper levels in angiographically defined obstructive coronary artery disease (CAD) in patients undergoing elective coronary angiography in El-Shaab Hospital, Sudan. We performed a cross-sectional study. One hundred forty-two patients were enrolled. Sociodemographic and medical characteristics were collected using a questionnaire. Glucose, lipid, zinc, and copper levels were measured. Out of 142 patients, 102 (71.8%) had CAD and 40 (28.2%) had patent coronary arteries. There were no significant differences in median (interquartile range) zinc [118.5 (97.2-151.0) vs. 130.0 (106.0-174.0) μg/ml, P = 0.120] and copper [150.6 (125.0-183.0) vs. 158 (132.0-180.0) μg/mL, P = 0.478] levels between patients with CAD and those with patent coronary arteries. In linear regression analysis, there were no associations between CAD and zinc and copper levels. The current study failed to show any significant association between CAD and zinc and copper levels.

No MeSH data available.


Related in: MedlinePlus

Zinc and copper levels in males and females.
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Figure 2: Zinc and copper levels in males and females.

Mentions: The general medical and biochemical characteristics of these 142 patients are shown in Table 1. The median (interquartile range) of zinc and copper levels was 128 μg/ml (103–162 μg/ml) and 156 μg/ml (131–180 μg/ml), respectively. Coronary catheterization showed that 101 (71.8%) patients had CAD and 40 (28.2%) patients had patent coronary arteries. Median zinc and copper levels were not significantly different between women and men, obese (BMI > 30.0 kg/m2) and non-obese patients, hypertensive and non-hypertensive patients, and diabetic and non-diabetic patients. Similarly, there were no significant difference in median zinc and copper levels in patients with CAD and in those with patent coronary arteries (Table 2, Figures 1, 2).


Zinc and copper levels are not correlated with angiographically-defined coronary artery disease in sudanese patients.

Lutfi MF, Elhakeem RF, Khogaly RS, Abdrabo AA, Ali AB, Gasim GI, Adam I - Front Physiol (2015)

Zinc and copper levels in males and females.
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4492078&req=5

Figure 2: Zinc and copper levels in males and females.
Mentions: The general medical and biochemical characteristics of these 142 patients are shown in Table 1. The median (interquartile range) of zinc and copper levels was 128 μg/ml (103–162 μg/ml) and 156 μg/ml (131–180 μg/ml), respectively. Coronary catheterization showed that 101 (71.8%) patients had CAD and 40 (28.2%) patients had patent coronary arteries. Median zinc and copper levels were not significantly different between women and men, obese (BMI > 30.0 kg/m2) and non-obese patients, hypertensive and non-hypertensive patients, and diabetic and non-diabetic patients. Similarly, there were no significant difference in median zinc and copper levels in patients with CAD and in those with patent coronary arteries (Table 2, Figures 1, 2).

Bottom Line: We performed a cross-sectional study.One hundred forty-two patients were enrolled.Sociodemographic and medical characteristics were collected using a questionnaire.

View Article: PubMed Central - PubMed

Affiliation: Faculty of Medicine, Alneelain University Khartoum, Sudan.

ABSTRACT
We investigated zinc and copper levels in angiographically defined obstructive coronary artery disease (CAD) in patients undergoing elective coronary angiography in El-Shaab Hospital, Sudan. We performed a cross-sectional study. One hundred forty-two patients were enrolled. Sociodemographic and medical characteristics were collected using a questionnaire. Glucose, lipid, zinc, and copper levels were measured. Out of 142 patients, 102 (71.8%) had CAD and 40 (28.2%) had patent coronary arteries. There were no significant differences in median (interquartile range) zinc [118.5 (97.2-151.0) vs. 130.0 (106.0-174.0) μg/ml, P = 0.120] and copper [150.6 (125.0-183.0) vs. 158 (132.0-180.0) μg/mL, P = 0.478] levels between patients with CAD and those with patent coronary arteries. In linear regression analysis, there were no associations between CAD and zinc and copper levels. The current study failed to show any significant association between CAD and zinc and copper levels.

No MeSH data available.


Related in: MedlinePlus