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A preliminary physicochemical evaluation of Darvyadi Yoni Varti: A compound Ayurvedic formulation.

Rupapara AV, Donga SB, Harisha CR, Shukla VJ - Ayu (2014 Oct-Dec)

Bottom Line: Finished product was analyzed by following pharmacopoeial standards.High performance thin layer chromatography was carried out; in which maximum 10 spots at 254 nm and 3 spots at 366 nm were distinguished.Pharmacognostical study of raw drug revealed the quality and genuineness of all the constituents of Darvyadi Yoni Varti.

View Article: PubMed Central - PubMed

Affiliation: Department of Streeroga and Prasootitantra, Parul Institute of Ayurveda, Limda, Vadodara, India.

ABSTRACT

Background: Darvyadi Yoni Varti is an Ayurvedic formulation indicated for the management of Garbhasaya Grivamukhagata Vrana (cervical erosion). Though a number of drugs are available in modern medicine, interest towards Ayurveda is gaining. Drugs with Vranasodhana, Ropana and Prasadana properties like Sphatika, Darvi, Haridra, and Lodhra are useful in this situation and are selected to prepare Yoni Varti.

Aim: To standardize and evaluate preliminary pharmacognostical as well as physicochemical profiles of Darvyadi Yoni Varti.

Materials and methods: Raw material was analyzed in the Pharmacognostical Laboratory for genuinity before converting into Varti. Finished product was analyzed by following pharmacopoeial standards.

Results: The pH value of Darvyadi Yoni Varti was 5.0, water soluble extract was 23.3%w/w, alcohol soluble extract was 8.7%w/w, ash value was 5.16%w/w, loss on drying was 71.73%w/w. High performance thin layer chromatography was carried out; in which maximum 10 spots at 254 nm and 3 spots at 366 nm were distinguished.

Conclusion: Pharmacognostical study of raw drug revealed the quality and genuineness of all the constituents of Darvyadi Yoni Varti.

No MeSH data available.


Related in: MedlinePlus

Densitometry at 254 nm
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Figure 13: Densitometry at 254 nm

Mentions: HPTLC under 254 nm showed 10 spots at 0.02, o. 45, 0.53, 0.64, 0.70, 0.79, 0.82, 0.087, 0.92 and 0.96 Rf values and under 366 nm showed 3 spots at 0.02, 0.45 and 0.92 Rf values [Table 4, Figures 13 and 14]. Mainly trigger phenolic acid and sterols type molecules and TLC patent obtained can be used as finger printing of the final product.


A preliminary physicochemical evaluation of Darvyadi Yoni Varti: A compound Ayurvedic formulation.

Rupapara AV, Donga SB, Harisha CR, Shukla VJ - Ayu (2014 Oct-Dec)

Densitometry at 254 nm
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4492037&req=5

Figure 13: Densitometry at 254 nm
Mentions: HPTLC under 254 nm showed 10 spots at 0.02, o. 45, 0.53, 0.64, 0.70, 0.79, 0.82, 0.087, 0.92 and 0.96 Rf values and under 366 nm showed 3 spots at 0.02, 0.45 and 0.92 Rf values [Table 4, Figures 13 and 14]. Mainly trigger phenolic acid and sterols type molecules and TLC patent obtained can be used as finger printing of the final product.

Bottom Line: Finished product was analyzed by following pharmacopoeial standards.High performance thin layer chromatography was carried out; in which maximum 10 spots at 254 nm and 3 spots at 366 nm were distinguished.Pharmacognostical study of raw drug revealed the quality and genuineness of all the constituents of Darvyadi Yoni Varti.

View Article: PubMed Central - PubMed

Affiliation: Department of Streeroga and Prasootitantra, Parul Institute of Ayurveda, Limda, Vadodara, India.

ABSTRACT

Background: Darvyadi Yoni Varti is an Ayurvedic formulation indicated for the management of Garbhasaya Grivamukhagata Vrana (cervical erosion). Though a number of drugs are available in modern medicine, interest towards Ayurveda is gaining. Drugs with Vranasodhana, Ropana and Prasadana properties like Sphatika, Darvi, Haridra, and Lodhra are useful in this situation and are selected to prepare Yoni Varti.

Aim: To standardize and evaluate preliminary pharmacognostical as well as physicochemical profiles of Darvyadi Yoni Varti.

Materials and methods: Raw material was analyzed in the Pharmacognostical Laboratory for genuinity before converting into Varti. Finished product was analyzed by following pharmacopoeial standards.

Results: The pH value of Darvyadi Yoni Varti was 5.0, water soluble extract was 23.3%w/w, alcohol soluble extract was 8.7%w/w, ash value was 5.16%w/w, loss on drying was 71.73%w/w. High performance thin layer chromatography was carried out; in which maximum 10 spots at 254 nm and 3 spots at 366 nm were distinguished.

Conclusion: Pharmacognostical study of raw drug revealed the quality and genuineness of all the constituents of Darvyadi Yoni Varti.

No MeSH data available.


Related in: MedlinePlus