Limits...
Prenatal screening tests may be a warning for the partial molar pregnancy? case report.

Sargin MA, Tug N, Yassa M, Yavuz A - Pan Afr Med J (2015)

Bottom Line: Prenatal screening tests are frequently requested for chromosomal abnormalities.Placental pathologies in early pregnancy may be overlooked, especially in partial molar pregnancy.We are reporting an incorrect preliminary diagnosed case with an increased risk of Down syndrome in her first-trimester screening test due to partial molar pregnancy.

View Article: PubMed Central - PubMed

Affiliation: Department of Obstetrics and Gynecology, Fatih Sultan Mehmet Research and Training Hospital, Istanbul, Turkey.

ABSTRACT
Prenatal screening tests are frequently requested for chromosomal abnormalities. Placental pathologies in early pregnancy may be overlooked, especially in partial molar pregnancy. We are reporting an incorrect preliminary diagnosed case with an increased risk of Down syndrome in her first-trimester screening test due to partial molar pregnancy.

No MeSH data available.


Related in: MedlinePlus

The thick swiss cheese pattern placenta
© Copyright Policy - open-access
Related In: Results  -  Collection

License
getmorefigures.php?uid=PMC4491477&req=5

Figure 0002: The thick swiss cheese pattern placenta

Mentions: A 27-year-old gravida 2, para 1 woman was referred to our hospital for further obstetric examination of her first-trimester screening test which was associated with an increased risk of Down syndrome. Her menstrual periods were regular, the first day of her last menstrual period was 14 weeks ago. The first trimester screening test value of B-hcg was 4, 3 MoM and correspondingly to this result, Down syndrome risk had been found 1/80. Transvaginal ultrasound examination showed a CRL 13 weeks plus 6 days alive fetus with septad cystic hygroma and hydrops fetalis (Figure 1). The thick Swiss-Cheese pattern placenta (Figure 2) and normal adnexa revealed. The preliminary diagnosis was considered as partial molar pregnancy. Patient was normotensive. In laboratory, serum B-hcg 550000 IU/ml, Hgb 12 gr/dl, decreased TSH and negatif proteinuria in urinanalysis found. There was no hyperthyroidism. Chest X-ray was unremarkable. Pregnancy termination and suction curetage planned under general anesthesia due to the fetal anomaly and prediagnosis of partial molar pregnancy. Oral misoprostol treatment began once every four hours. After abortion, suction curettage was performed. Patient was discharged on the first postoperative day. Histopathological examination results indicated partial molar pregnancy. Karyotype analysis could not be performed because the placenta was received fixed in formalin. Patient was followed up for 48 hours after the evacuation and weekly until serum B-hcg has fallen to undetectable levels. Twelfth week B-hcg value was negative. Once undetectable level was attained, follow up was continued monthly for an additional 9 months. The mean follow up period of the patient's was one year.


Prenatal screening tests may be a warning for the partial molar pregnancy? case report.

Sargin MA, Tug N, Yassa M, Yavuz A - Pan Afr Med J (2015)

The thick swiss cheese pattern placenta
© Copyright Policy - open-access
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4491477&req=5

Figure 0002: The thick swiss cheese pattern placenta
Mentions: A 27-year-old gravida 2, para 1 woman was referred to our hospital for further obstetric examination of her first-trimester screening test which was associated with an increased risk of Down syndrome. Her menstrual periods were regular, the first day of her last menstrual period was 14 weeks ago. The first trimester screening test value of B-hcg was 4, 3 MoM and correspondingly to this result, Down syndrome risk had been found 1/80. Transvaginal ultrasound examination showed a CRL 13 weeks plus 6 days alive fetus with septad cystic hygroma and hydrops fetalis (Figure 1). The thick Swiss-Cheese pattern placenta (Figure 2) and normal adnexa revealed. The preliminary diagnosis was considered as partial molar pregnancy. Patient was normotensive. In laboratory, serum B-hcg 550000 IU/ml, Hgb 12 gr/dl, decreased TSH and negatif proteinuria in urinanalysis found. There was no hyperthyroidism. Chest X-ray was unremarkable. Pregnancy termination and suction curetage planned under general anesthesia due to the fetal anomaly and prediagnosis of partial molar pregnancy. Oral misoprostol treatment began once every four hours. After abortion, suction curettage was performed. Patient was discharged on the first postoperative day. Histopathological examination results indicated partial molar pregnancy. Karyotype analysis could not be performed because the placenta was received fixed in formalin. Patient was followed up for 48 hours after the evacuation and weekly until serum B-hcg has fallen to undetectable levels. Twelfth week B-hcg value was negative. Once undetectable level was attained, follow up was continued monthly for an additional 9 months. The mean follow up period of the patient's was one year.

Bottom Line: Prenatal screening tests are frequently requested for chromosomal abnormalities.Placental pathologies in early pregnancy may be overlooked, especially in partial molar pregnancy.We are reporting an incorrect preliminary diagnosed case with an increased risk of Down syndrome in her first-trimester screening test due to partial molar pregnancy.

View Article: PubMed Central - PubMed

Affiliation: Department of Obstetrics and Gynecology, Fatih Sultan Mehmet Research and Training Hospital, Istanbul, Turkey.

ABSTRACT
Prenatal screening tests are frequently requested for chromosomal abnormalities. Placental pathologies in early pregnancy may be overlooked, especially in partial molar pregnancy. We are reporting an incorrect preliminary diagnosed case with an increased risk of Down syndrome in her first-trimester screening test due to partial molar pregnancy.

No MeSH data available.


Related in: MedlinePlus