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Free-Breathing 3D Imaging of Right Ventricular Structure and Function Using Respiratory and Cardiac Self-Gated Cine MRI.

Zhu Y, Liu J, Weinsaft J, Spincemaille P, Nguyen TD, Prince MR, Bao S, Xie Y, Wang Y - Biomed Res Int (2015)

Bottom Line: Providing a movie of the beating heart in a single prescribed plane, cine MRI has been widely used in clinical cardiac diagnosis, especially in the left ventricle (LV).High correlations between the two techniques were found (RVEDV: 0.94; RVESV: 0.85; RVSV: 0.95; and RVEF: 0.89).Compared with 2D, the 3D image quality measurements show a small reduction in blood SNR, myocardium-blood CNR, myocardium contrast, and image sharpness.

View Article: PubMed Central - PubMed

Affiliation: Institute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, 1068 Xueyuan Avenue, Shenzhen University Town, Nanshan District, Shenzhen 518055, China ; Beijing City Key Lab of Medical Physics and Engineering, School of Physics, Peking University, 201 Chengfu Road, Haidian District, Beijing 100871, China ; Department of Radiology, Weill Cornell Medical College, 515 East 71th Street, New York, NY 10021, USA.

ABSTRACT
Providing a movie of the beating heart in a single prescribed plane, cine MRI has been widely used in clinical cardiac diagnosis, especially in the left ventricle (LV). Right ventricular (RV) morphology and function are also important for the diagnosis of cardiopulmonary diseases and serve as predictors for the long term outcome. The purpose of this study is to develop a self-gated free-breathing 3D imaging method for RV quantification and to evaluate its performance by comparing it with breath-hold 2D cine imaging in 7 healthy volunteers. Compared with 2D, the 3D RV functional measurements show a reduction of RV end-diastole volume (RVEDV) by 10%, increase of RV end-systole volume (RVESV) by 1.8%, reduction of RV systole volume (RVSV) by 21%, and reduction of RV ejection fraction (RVEF) by 12%. High correlations between the two techniques were found (RVEDV: 0.94; RVESV: 0.85; RVSV: 0.95; and RVEF: 0.89). Compared with 2D, the 3D image quality measurements show a small reduction in blood SNR, myocardium-blood CNR, myocardium contrast, and image sharpness. In conclusion, the proposed self-gated free-breathing 3D cardiac cine imaging technique provides comparable image quality and correlated functional measurements to those acquired with the multiple breath-hold 2D technique in RV.

No MeSH data available.


Related in: MedlinePlus

Images of mid-ventricular slices obtained with 2D and 3D cine imaging during end-diastole (a, c) and end-systole (b, d) in seven healthy volunteers.
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fig8: Images of mid-ventricular slices obtained with 2D and 3D cine imaging during end-diastole (a, c) and end-systole (b, d) in seven healthy volunteers.

Mentions: Figure 8 shows the comparison of mid-ventricular slices obtained during end-diastolic and end-systolic cardiac phases from seven volunteers. A few streaking artifacts appear in 3D self-gated images due to undersampling (undersampling ratio: 2~3) and motion. Table 2 shows image quality measurements from mid-ventricular images in Figure 8. Compared with 2D, the 3D image quality measurements show a small reduction in blood SNR, myocardium-blood CNR, myocardium contrast, and image sharpness. Compared with other image quality measurements, differences of myocardium-blood CNR and contrast measurements in end-diastole images were statistically significant (P < 0.05).


Free-Breathing 3D Imaging of Right Ventricular Structure and Function Using Respiratory and Cardiac Self-Gated Cine MRI.

Zhu Y, Liu J, Weinsaft J, Spincemaille P, Nguyen TD, Prince MR, Bao S, Xie Y, Wang Y - Biomed Res Int (2015)

Images of mid-ventricular slices obtained with 2D and 3D cine imaging during end-diastole (a, c) and end-systole (b, d) in seven healthy volunteers.
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4491385&req=5

fig8: Images of mid-ventricular slices obtained with 2D and 3D cine imaging during end-diastole (a, c) and end-systole (b, d) in seven healthy volunteers.
Mentions: Figure 8 shows the comparison of mid-ventricular slices obtained during end-diastolic and end-systolic cardiac phases from seven volunteers. A few streaking artifacts appear in 3D self-gated images due to undersampling (undersampling ratio: 2~3) and motion. Table 2 shows image quality measurements from mid-ventricular images in Figure 8. Compared with 2D, the 3D image quality measurements show a small reduction in blood SNR, myocardium-blood CNR, myocardium contrast, and image sharpness. Compared with other image quality measurements, differences of myocardium-blood CNR and contrast measurements in end-diastole images were statistically significant (P < 0.05).

Bottom Line: Providing a movie of the beating heart in a single prescribed plane, cine MRI has been widely used in clinical cardiac diagnosis, especially in the left ventricle (LV).High correlations between the two techniques were found (RVEDV: 0.94; RVESV: 0.85; RVSV: 0.95; and RVEF: 0.89).Compared with 2D, the 3D image quality measurements show a small reduction in blood SNR, myocardium-blood CNR, myocardium contrast, and image sharpness.

View Article: PubMed Central - PubMed

Affiliation: Institute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, 1068 Xueyuan Avenue, Shenzhen University Town, Nanshan District, Shenzhen 518055, China ; Beijing City Key Lab of Medical Physics and Engineering, School of Physics, Peking University, 201 Chengfu Road, Haidian District, Beijing 100871, China ; Department of Radiology, Weill Cornell Medical College, 515 East 71th Street, New York, NY 10021, USA.

ABSTRACT
Providing a movie of the beating heart in a single prescribed plane, cine MRI has been widely used in clinical cardiac diagnosis, especially in the left ventricle (LV). Right ventricular (RV) morphology and function are also important for the diagnosis of cardiopulmonary diseases and serve as predictors for the long term outcome. The purpose of this study is to develop a self-gated free-breathing 3D imaging method for RV quantification and to evaluate its performance by comparing it with breath-hold 2D cine imaging in 7 healthy volunteers. Compared with 2D, the 3D RV functional measurements show a reduction of RV end-diastole volume (RVEDV) by 10%, increase of RV end-systole volume (RVESV) by 1.8%, reduction of RV systole volume (RVSV) by 21%, and reduction of RV ejection fraction (RVEF) by 12%. High correlations between the two techniques were found (RVEDV: 0.94; RVESV: 0.85; RVSV: 0.95; and RVEF: 0.89). Compared with 2D, the 3D image quality measurements show a small reduction in blood SNR, myocardium-blood CNR, myocardium contrast, and image sharpness. In conclusion, the proposed self-gated free-breathing 3D cardiac cine imaging technique provides comparable image quality and correlated functional measurements to those acquired with the multiple breath-hold 2D technique in RV.

No MeSH data available.


Related in: MedlinePlus