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Free-Breathing 3D Imaging of Right Ventricular Structure and Function Using Respiratory and Cardiac Self-Gated Cine MRI.

Zhu Y, Liu J, Weinsaft J, Spincemaille P, Nguyen TD, Prince MR, Bao S, Xie Y, Wang Y - Biomed Res Int (2015)

Bottom Line: Providing a movie of the beating heart in a single prescribed plane, cine MRI has been widely used in clinical cardiac diagnosis, especially in the left ventricle (LV).High correlations between the two techniques were found (RVEDV: 0.94; RVESV: 0.85; RVSV: 0.95; and RVEF: 0.89).Compared with 2D, the 3D image quality measurements show a small reduction in blood SNR, myocardium-blood CNR, myocardium contrast, and image sharpness.

View Article: PubMed Central - PubMed

Affiliation: Institute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, 1068 Xueyuan Avenue, Shenzhen University Town, Nanshan District, Shenzhen 518055, China ; Beijing City Key Lab of Medical Physics and Engineering, School of Physics, Peking University, 201 Chengfu Road, Haidian District, Beijing 100871, China ; Department of Radiology, Weill Cornell Medical College, 515 East 71th Street, New York, NY 10021, USA.

ABSTRACT
Providing a movie of the beating heart in a single prescribed plane, cine MRI has been widely used in clinical cardiac diagnosis, especially in the left ventricle (LV). Right ventricular (RV) morphology and function are also important for the diagnosis of cardiopulmonary diseases and serve as predictors for the long term outcome. The purpose of this study is to develop a self-gated free-breathing 3D imaging method for RV quantification and to evaluate its performance by comparing it with breath-hold 2D cine imaging in 7 healthy volunteers. Compared with 2D, the 3D RV functional measurements show a reduction of RV end-diastole volume (RVEDV) by 10%, increase of RV end-systole volume (RVESV) by 1.8%, reduction of RV systole volume (RVSV) by 21%, and reduction of RV ejection fraction (RVEF) by 12%. High correlations between the two techniques were found (RVEDV: 0.94; RVESV: 0.85; RVSV: 0.95; and RVEF: 0.89). Compared with 2D, the 3D image quality measurements show a small reduction in blood SNR, myocardium-blood CNR, myocardium contrast, and image sharpness. In conclusion, the proposed self-gated free-breathing 3D cardiac cine imaging technique provides comparable image quality and correlated functional measurements to those acquired with the multiple breath-hold 2D technique in RV.

No MeSH data available.


Related in: MedlinePlus

Comparison of systolic and diastolic RV areas obtained at different slice locations using breath-hold 2D and self-gated free-breathing 3D cine imaging.
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fig6: Comparison of systolic and diastolic RV areas obtained at different slice locations using breath-hold 2D and self-gated free-breathing 3D cine imaging.

Mentions: Figure 6 shows the comparison of RV areas in different slice locations between breath-hold 2D and self-gated free-breathing 3D methods. Average RV diastole and systole areas are shown as red curves for 2D and blue curves for 3D. RV systolic area curves of 2D and 3D fit well and the volumes are similar, with bias of −1.1 ± 6.4 mL (as shown in Table 1). Compared with systole, diastolic areas measured in 2D cine images are larger, especially towards the cardiac apex and base, which causes 2D RVEDV to be higher than 3D with bias of 15.1 ± 8.5 mL, as shown in Table 1.


Free-Breathing 3D Imaging of Right Ventricular Structure and Function Using Respiratory and Cardiac Self-Gated Cine MRI.

Zhu Y, Liu J, Weinsaft J, Spincemaille P, Nguyen TD, Prince MR, Bao S, Xie Y, Wang Y - Biomed Res Int (2015)

Comparison of systolic and diastolic RV areas obtained at different slice locations using breath-hold 2D and self-gated free-breathing 3D cine imaging.
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4491385&req=5

fig6: Comparison of systolic and diastolic RV areas obtained at different slice locations using breath-hold 2D and self-gated free-breathing 3D cine imaging.
Mentions: Figure 6 shows the comparison of RV areas in different slice locations between breath-hold 2D and self-gated free-breathing 3D methods. Average RV diastole and systole areas are shown as red curves for 2D and blue curves for 3D. RV systolic area curves of 2D and 3D fit well and the volumes are similar, with bias of −1.1 ± 6.4 mL (as shown in Table 1). Compared with systole, diastolic areas measured in 2D cine images are larger, especially towards the cardiac apex and base, which causes 2D RVEDV to be higher than 3D with bias of 15.1 ± 8.5 mL, as shown in Table 1.

Bottom Line: Providing a movie of the beating heart in a single prescribed plane, cine MRI has been widely used in clinical cardiac diagnosis, especially in the left ventricle (LV).High correlations between the two techniques were found (RVEDV: 0.94; RVESV: 0.85; RVSV: 0.95; and RVEF: 0.89).Compared with 2D, the 3D image quality measurements show a small reduction in blood SNR, myocardium-blood CNR, myocardium contrast, and image sharpness.

View Article: PubMed Central - PubMed

Affiliation: Institute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, 1068 Xueyuan Avenue, Shenzhen University Town, Nanshan District, Shenzhen 518055, China ; Beijing City Key Lab of Medical Physics and Engineering, School of Physics, Peking University, 201 Chengfu Road, Haidian District, Beijing 100871, China ; Department of Radiology, Weill Cornell Medical College, 515 East 71th Street, New York, NY 10021, USA.

ABSTRACT
Providing a movie of the beating heart in a single prescribed plane, cine MRI has been widely used in clinical cardiac diagnosis, especially in the left ventricle (LV). Right ventricular (RV) morphology and function are also important for the diagnosis of cardiopulmonary diseases and serve as predictors for the long term outcome. The purpose of this study is to develop a self-gated free-breathing 3D imaging method for RV quantification and to evaluate its performance by comparing it with breath-hold 2D cine imaging in 7 healthy volunteers. Compared with 2D, the 3D RV functional measurements show a reduction of RV end-diastole volume (RVEDV) by 10%, increase of RV end-systole volume (RVESV) by 1.8%, reduction of RV systole volume (RVSV) by 21%, and reduction of RV ejection fraction (RVEF) by 12%. High correlations between the two techniques were found (RVEDV: 0.94; RVESV: 0.85; RVSV: 0.95; and RVEF: 0.89). Compared with 2D, the 3D image quality measurements show a small reduction in blood SNR, myocardium-blood CNR, myocardium contrast, and image sharpness. In conclusion, the proposed self-gated free-breathing 3D cardiac cine imaging technique provides comparable image quality and correlated functional measurements to those acquired with the multiple breath-hold 2D technique in RV.

No MeSH data available.


Related in: MedlinePlus