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Free-Breathing 3D Imaging of Right Ventricular Structure and Function Using Respiratory and Cardiac Self-Gated Cine MRI.

Zhu Y, Liu J, Weinsaft J, Spincemaille P, Nguyen TD, Prince MR, Bao S, Xie Y, Wang Y - Biomed Res Int (2015)

Bottom Line: Compared with 2D, the 3D RV functional measurements show a reduction of RV end-diastole volume (RVEDV) by 10%, increase of RV end-systole volume (RVESV) by 1.8%, reduction of RV systole volume (RVSV) by 21%, and reduction of RV ejection fraction (RVEF) by 12%.High correlations between the two techniques were found (RVEDV: 0.94; RVESV: 0.85; RVSV: 0.95; and RVEF: 0.89).Compared with 2D, the 3D image quality measurements show a small reduction in blood SNR, myocardium-blood CNR, myocardium contrast, and image sharpness.

View Article: PubMed Central - PubMed

Affiliation: Institute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, 1068 Xueyuan Avenue, Shenzhen University Town, Nanshan District, Shenzhen 518055, China ; Beijing City Key Lab of Medical Physics and Engineering, School of Physics, Peking University, 201 Chengfu Road, Haidian District, Beijing 100871, China ; Department of Radiology, Weill Cornell Medical College, 515 East 71th Street, New York, NY 10021, USA.

ABSTRACT
Providing a movie of the beating heart in a single prescribed plane, cine MRI has been widely used in clinical cardiac diagnosis, especially in the left ventricle (LV). Right ventricular (RV) morphology and function are also important for the diagnosis of cardiopulmonary diseases and serve as predictors for the long term outcome. The purpose of this study is to develop a self-gated free-breathing 3D imaging method for RV quantification and to evaluate its performance by comparing it with breath-hold 2D cine imaging in 7 healthy volunteers. Compared with 2D, the 3D RV functional measurements show a reduction of RV end-diastole volume (RVEDV) by 10%, increase of RV end-systole volume (RVESV) by 1.8%, reduction of RV systole volume (RVSV) by 21%, and reduction of RV ejection fraction (RVEF) by 12%. High correlations between the two techniques were found (RVEDV: 0.94; RVESV: 0.85; RVSV: 0.95; and RVEF: 0.89). Compared with 2D, the 3D image quality measurements show a small reduction in blood SNR, myocardium-blood CNR, myocardium contrast, and image sharpness. In conclusion, the proposed self-gated free-breathing 3D cardiac cine imaging technique provides comparable image quality and correlated functional measurements to those acquired with the multiple breath-hold 2D technique in RV.

No MeSH data available.


Related in: MedlinePlus

Schematic diagram of tornado temporal filter in sliding window reconstruction of pth cardiac phase (a) and corresponding k-space distribution (b).
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Related In: Results  -  Collection


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fig3: Schematic diagram of tornado temporal filter in sliding window reconstruction of pth cardiac phase (a) and corresponding k-space distribution (b).

Mentions: The detected respiratory and cardiac motion signals were used to determine the respiratory position and cardiac phase associated with each profile. A respiratory histogram was calculated and only data acquired within a given window (50% of acquired data) around the peak of the histogram were used for image reconstruction. The profiles detected with the same cardiac phase number, according to the self-gated cardiac motion signal, were used for reconstruction. Sliding window reconstruction with tornado temporal filter [16] (Figure 3(a)) was applied to decrease the streaking artifacts caused by undersampling in the kx-ky plane. The temporal aperture was the specified cardiac phase (pth) beginning at the lowest spatial frequency and increasing linearly to the highest spatial frequency (Figure 3(a)). The corresponding k-space distribution for the pth cardiac phase reconstruction was depicted in Figure 3(b). The proportion of high spatial frequency k-space data shared from neighboring cardiac phases (one-third of the number of cardiac phases) was related to cardiac phase distance. Temporal resolution of each cardiac phase image was calculated as center period of tornado window, which spent nzTR. Images were reconstructed from radial k-space data using gridding algorithm [17] with Kaiser-Bessel window as a gridding kernel.


Free-Breathing 3D Imaging of Right Ventricular Structure and Function Using Respiratory and Cardiac Self-Gated Cine MRI.

Zhu Y, Liu J, Weinsaft J, Spincemaille P, Nguyen TD, Prince MR, Bao S, Xie Y, Wang Y - Biomed Res Int (2015)

Schematic diagram of tornado temporal filter in sliding window reconstruction of pth cardiac phase (a) and corresponding k-space distribution (b).
© Copyright Policy - open-access
Related In: Results  -  Collection

Show All Figures
getmorefigures.php?uid=PMC4491385&req=5

fig3: Schematic diagram of tornado temporal filter in sliding window reconstruction of pth cardiac phase (a) and corresponding k-space distribution (b).
Mentions: The detected respiratory and cardiac motion signals were used to determine the respiratory position and cardiac phase associated with each profile. A respiratory histogram was calculated and only data acquired within a given window (50% of acquired data) around the peak of the histogram were used for image reconstruction. The profiles detected with the same cardiac phase number, according to the self-gated cardiac motion signal, were used for reconstruction. Sliding window reconstruction with tornado temporal filter [16] (Figure 3(a)) was applied to decrease the streaking artifacts caused by undersampling in the kx-ky plane. The temporal aperture was the specified cardiac phase (pth) beginning at the lowest spatial frequency and increasing linearly to the highest spatial frequency (Figure 3(a)). The corresponding k-space distribution for the pth cardiac phase reconstruction was depicted in Figure 3(b). The proportion of high spatial frequency k-space data shared from neighboring cardiac phases (one-third of the number of cardiac phases) was related to cardiac phase distance. Temporal resolution of each cardiac phase image was calculated as center period of tornado window, which spent nzTR. Images were reconstructed from radial k-space data using gridding algorithm [17] with Kaiser-Bessel window as a gridding kernel.

Bottom Line: Compared with 2D, the 3D RV functional measurements show a reduction of RV end-diastole volume (RVEDV) by 10%, increase of RV end-systole volume (RVESV) by 1.8%, reduction of RV systole volume (RVSV) by 21%, and reduction of RV ejection fraction (RVEF) by 12%.High correlations between the two techniques were found (RVEDV: 0.94; RVESV: 0.85; RVSV: 0.95; and RVEF: 0.89).Compared with 2D, the 3D image quality measurements show a small reduction in blood SNR, myocardium-blood CNR, myocardium contrast, and image sharpness.

View Article: PubMed Central - PubMed

Affiliation: Institute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, 1068 Xueyuan Avenue, Shenzhen University Town, Nanshan District, Shenzhen 518055, China ; Beijing City Key Lab of Medical Physics and Engineering, School of Physics, Peking University, 201 Chengfu Road, Haidian District, Beijing 100871, China ; Department of Radiology, Weill Cornell Medical College, 515 East 71th Street, New York, NY 10021, USA.

ABSTRACT
Providing a movie of the beating heart in a single prescribed plane, cine MRI has been widely used in clinical cardiac diagnosis, especially in the left ventricle (LV). Right ventricular (RV) morphology and function are also important for the diagnosis of cardiopulmonary diseases and serve as predictors for the long term outcome. The purpose of this study is to develop a self-gated free-breathing 3D imaging method for RV quantification and to evaluate its performance by comparing it with breath-hold 2D cine imaging in 7 healthy volunteers. Compared with 2D, the 3D RV functional measurements show a reduction of RV end-diastole volume (RVEDV) by 10%, increase of RV end-systole volume (RVESV) by 1.8%, reduction of RV systole volume (RVSV) by 21%, and reduction of RV ejection fraction (RVEF) by 12%. High correlations between the two techniques were found (RVEDV: 0.94; RVESV: 0.85; RVSV: 0.95; and RVEF: 0.89). Compared with 2D, the 3D image quality measurements show a small reduction in blood SNR, myocardium-blood CNR, myocardium contrast, and image sharpness. In conclusion, the proposed self-gated free-breathing 3D cardiac cine imaging technique provides comparable image quality and correlated functional measurements to those acquired with the multiple breath-hold 2D technique in RV.

No MeSH data available.


Related in: MedlinePlus