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Free-Breathing 3D Imaging of Right Ventricular Structure and Function Using Respiratory and Cardiac Self-Gated Cine MRI.

Zhu Y, Liu J, Weinsaft J, Spincemaille P, Nguyen TD, Prince MR, Bao S, Xie Y, Wang Y - Biomed Res Int (2015)

Bottom Line: Providing a movie of the beating heart in a single prescribed plane, cine MRI has been widely used in clinical cardiac diagnosis, especially in the left ventricle (LV).High correlations between the two techniques were found (RVEDV: 0.94; RVESV: 0.85; RVSV: 0.95; and RVEF: 0.89).Compared with 2D, the 3D image quality measurements show a small reduction in blood SNR, myocardium-blood CNR, myocardium contrast, and image sharpness.

View Article: PubMed Central - PubMed

Affiliation: Institute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, 1068 Xueyuan Avenue, Shenzhen University Town, Nanshan District, Shenzhen 518055, China ; Beijing City Key Lab of Medical Physics and Engineering, School of Physics, Peking University, 201 Chengfu Road, Haidian District, Beijing 100871, China ; Department of Radiology, Weill Cornell Medical College, 515 East 71th Street, New York, NY 10021, USA.

ABSTRACT
Providing a movie of the beating heart in a single prescribed plane, cine MRI has been widely used in clinical cardiac diagnosis, especially in the left ventricle (LV). Right ventricular (RV) morphology and function are also important for the diagnosis of cardiopulmonary diseases and serve as predictors for the long term outcome. The purpose of this study is to develop a self-gated free-breathing 3D imaging method for RV quantification and to evaluate its performance by comparing it with breath-hold 2D cine imaging in 7 healthy volunteers. Compared with 2D, the 3D RV functional measurements show a reduction of RV end-diastole volume (RVEDV) by 10%, increase of RV end-systole volume (RVESV) by 1.8%, reduction of RV systole volume (RVSV) by 21%, and reduction of RV ejection fraction (RVEF) by 12%. High correlations between the two techniques were found (RVEDV: 0.94; RVESV: 0.85; RVSV: 0.95; and RVEF: 0.89). Compared with 2D, the 3D image quality measurements show a small reduction in blood SNR, myocardium-blood CNR, myocardium contrast, and image sharpness. In conclusion, the proposed self-gated free-breathing 3D cardiac cine imaging technique provides comparable image quality and correlated functional measurements to those acquired with the multiple breath-hold 2D technique in RV.

No MeSH data available.


Related in: MedlinePlus

SSFP pulse sequence collects a profile with multiple slice encoding lines for a specific projection angle (blue lines in (a)) and changed projection angle after finishing the last profile (green lines in (b)).
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fig1: SSFP pulse sequence collects a profile with multiple slice encoding lines for a specific projection angle (blue lines in (a)) and changed projection angle after finishing the last profile (green lines in (b)).

Mentions: Figure 1 shows the pulse sequence diagram of the implemented self-gated 3D SSFP cine pulse sequence with hybrid radial k-space sampling (Cartesian sampling along slice encoding direction (kz) and radial sampling in the kx-ky plane) [12, 13]. All slice encodes for a given projection angle are acquired sequentially (Figure 1(a)) and named as a profile. The acquisition then switches to the next projection angle (Figure 1(b)) and acquires the next profile. Each profile including nz slice encodes spends the time of nz TR. The projection angle is increased by the golden angle of 111.2° to generate approximately uniform k-space distribution of the projections at any time point, allowing for robust sliding window reconstructions to achieve the desired temporal resolution and/or undersampling artifacts [14].


Free-Breathing 3D Imaging of Right Ventricular Structure and Function Using Respiratory and Cardiac Self-Gated Cine MRI.

Zhu Y, Liu J, Weinsaft J, Spincemaille P, Nguyen TD, Prince MR, Bao S, Xie Y, Wang Y - Biomed Res Int (2015)

SSFP pulse sequence collects a profile with multiple slice encoding lines for a specific projection angle (blue lines in (a)) and changed projection angle after finishing the last profile (green lines in (b)).
© Copyright Policy
Related In: Results  -  Collection

License
Show All Figures
getmorefigures.php?uid=PMC4491385&req=5

fig1: SSFP pulse sequence collects a profile with multiple slice encoding lines for a specific projection angle (blue lines in (a)) and changed projection angle after finishing the last profile (green lines in (b)).
Mentions: Figure 1 shows the pulse sequence diagram of the implemented self-gated 3D SSFP cine pulse sequence with hybrid radial k-space sampling (Cartesian sampling along slice encoding direction (kz) and radial sampling in the kx-ky plane) [12, 13]. All slice encodes for a given projection angle are acquired sequentially (Figure 1(a)) and named as a profile. The acquisition then switches to the next projection angle (Figure 1(b)) and acquires the next profile. Each profile including nz slice encodes spends the time of nz TR. The projection angle is increased by the golden angle of 111.2° to generate approximately uniform k-space distribution of the projections at any time point, allowing for robust sliding window reconstructions to achieve the desired temporal resolution and/or undersampling artifacts [14].

Bottom Line: Providing a movie of the beating heart in a single prescribed plane, cine MRI has been widely used in clinical cardiac diagnosis, especially in the left ventricle (LV).High correlations between the two techniques were found (RVEDV: 0.94; RVESV: 0.85; RVSV: 0.95; and RVEF: 0.89).Compared with 2D, the 3D image quality measurements show a small reduction in blood SNR, myocardium-blood CNR, myocardium contrast, and image sharpness.

View Article: PubMed Central - PubMed

Affiliation: Institute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, 1068 Xueyuan Avenue, Shenzhen University Town, Nanshan District, Shenzhen 518055, China ; Beijing City Key Lab of Medical Physics and Engineering, School of Physics, Peking University, 201 Chengfu Road, Haidian District, Beijing 100871, China ; Department of Radiology, Weill Cornell Medical College, 515 East 71th Street, New York, NY 10021, USA.

ABSTRACT
Providing a movie of the beating heart in a single prescribed plane, cine MRI has been widely used in clinical cardiac diagnosis, especially in the left ventricle (LV). Right ventricular (RV) morphology and function are also important for the diagnosis of cardiopulmonary diseases and serve as predictors for the long term outcome. The purpose of this study is to develop a self-gated free-breathing 3D imaging method for RV quantification and to evaluate its performance by comparing it with breath-hold 2D cine imaging in 7 healthy volunteers. Compared with 2D, the 3D RV functional measurements show a reduction of RV end-diastole volume (RVEDV) by 10%, increase of RV end-systole volume (RVESV) by 1.8%, reduction of RV systole volume (RVSV) by 21%, and reduction of RV ejection fraction (RVEF) by 12%. High correlations between the two techniques were found (RVEDV: 0.94; RVESV: 0.85; RVSV: 0.95; and RVEF: 0.89). Compared with 2D, the 3D image quality measurements show a small reduction in blood SNR, myocardium-blood CNR, myocardium contrast, and image sharpness. In conclusion, the proposed self-gated free-breathing 3D cardiac cine imaging technique provides comparable image quality and correlated functional measurements to those acquired with the multiple breath-hold 2D technique in RV.

No MeSH data available.


Related in: MedlinePlus