Burden of illness associated with peripheral and central neuropathic pain among adults seeking treatment in the United States: a patient-centered evaluation.
Bottom Line: Patient-reported outcomes (health status, physical and mental health, pain interference with function, sleep, anxiety, and depression) were significantly worse among subjects with greater pain severity (all P < 0.0001).Severe pain subjects were negatively impacted by ≥30% in each outcome compared with mild pain subjects; standardized effect size was moderate for anxiety (0.59) and large (>0.95) for all others.Subjects across NeP conditions exhibited high pain levels, which were significantly associated with poor function, compromised health status and sleep, and increased anxiety and depression.
Affiliation: Covance Market Access Services Inc., Gaithersburg, Maryland, USA.Show MeSH
Related in: MedlinePlus
Mentions: The mean pain interference scores for each of the NeP conditions are presented in Figure 3. Mean scores exhibited a similar pattern across NeP conditions and were consistently the highest/worst among CLBP-NeP subjects.
Affiliation: Covance Market Access Services Inc., Gaithersburg, Maryland, USA.